- Vaccine Ontology ID: VO_0004678
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: None
- Vector:
- Preparation: Inactivated SARS coronavirus (SARS-CoV) vaccine with adjuvant (Zheng et al., 2008).
- Immunization Route: Intramuscular injection (i.m.)
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- Vaccine Ontology ID: VO_0004679
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: None
- Vector:
- Preparation: RBD-rAAV prime/RBD-specific T cell peptide boost (Du et al., 2008).
- Immunization Route: Intramuscular injection (i.m.)
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- Vaccine Ontology ID: VO_0004711
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: None
- S protein gene of SARS-CoV
gene engineering:
- Type: Recombinant vector construction
- Description: A live attenuated recombinant meas(Escriou et al., 2014)s vaccine (MV) candidates expressing either the membrane-anchore SARS-CoV spike (S) protein (Escriou et al., 2014).
- Detailed Gene Information: Click Here.
- Vector:
- Preparation: Live attenuated recombinant measles vaccine (MV) candidates expressing either the membrane-anchored SARS-CoV spike (S) protein or its secreted soluble ectodomain (Ssol) (Escriou et al., 2014).
- Immunization Route: Intramuscular injection (i.m.)
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Zheng et al., 2008: Zheng BJ, Du LY, Zhao GY, Lin YP, Sui HY, Chan C, Ma S, Guan Y, Yuen KY. Studies of SARS virus vaccines. Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine. 2008; 14 Suppl 4; 39-43. [PubMed: 18708674].
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Du et al., 2008: Du L, Zhao G, Lin Y, Chan C, He Y, Jiang S, Wu C, Jin DY, Yuen KY, Zhou Y, Zheng BJ. Priming with rAAV encoding RBD of SARS-CoV S protein and boosting with RBD-specific peptides for T cell epitopes elevated humoral and cellular immune responses against SARS-CoV infection. Vaccine. 2008; 26(13); 1644-1651. [PubMed: 18289745].
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Escriou et al., 2014: Escriou N, Callendret B, Lorin V, Combredet C, Marianneau P, Février M, Tangy F. Protection from SARS coronavirus conferred by live measles vaccine expressing the spike glycoprotein. Virology. 2014; 452-453; 32-41. [PubMed: 24606680].
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