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Vaccine Comparison

BV-GD-ORF2 PrV-PCV2-ORF2
Vaccine Information Vaccine Information
  • Vaccine Ontology ID: VO_0004754
  • Type: Recombinant vector vaccine
  • Status: Research
  • Host Species for Licensed Use: Baboon
  • Vector:
  • Preparation: B aculovirus was used to develop a novel candidate vaccine for a preventive or therapeutic strategy to control PCV2 infections (Ye et al., 2013).
  • Immunization Route: Intramuscular injection (i.m.)
  • Vaccine Ontology ID: VO_0004699
  • Type: Recombinant vector vaccine
  • Status: Research
  • Host Species for Licensed Use: Baboon
  • ORF2 gene engineering:
    • Type: Recombinant vector construction
    • Description: PCV2 ORF2 gene was inserted into vector pG to produce the recombinant PRV vector pGO; the genome of PRV attenuated vaccine and the transfer plasmid pGO were transfected by using Lipofectamine 2000 Reagent into swine testis cells for homologous recombination to obtain the recombinant PRV (Chao et al., 2014).
    • Detailed Gene Information: Click Here.
  • Vector:
  • Preparation: PCV2 ORF2 gene was inserted into vector pG to produce the recombinant PRV vector pGO (Chao et al., 2014).
  • Immunization Route: Intramuscular injection (i.m.)
References References
Ye et al., 2013: Ye Y, Cheng X, Zhang J, Tong T, Lin W, Liao M, Fan H. Induction of robust immunity response in mice by dual-expression-system-based recombinant baculovirus expressing the capsid protein of porcine circovirus type 2. Virology journal. 2013; 10; 316. [PubMed: 24161107].
Chao et al., 2014: Chao A, Fu P, Guo X, Gao X, Cui B, Chen H. [Immune efficacy in mice by recombinant pseudorabies virus PGO expressing ORF2 gene of porcine circovirus type 2]. Wei sheng wu xue bao = Acta microbiologica Sinica. 2014; 54(2); 211-217. [PubMed: 24818470].