Vaxvec

Vaccine Comparison

CAdVax-RVFV glycoprotein	rMVA-GnGc (Rift Valley fever virus)
Vaccine Information	Vaccine Information
Vaccine Ontology ID: VO_0004642 Type: Recombinant vector vaccine Status: Research Host Species for Licensed Use: Baboon Vector: complex adenovirus vaccine vector Vactor Name: complex adenovirus vaccine vector VO ID: VO_0001086 Preparation: RVFV glycoprotein genes were incorporated into a nonreplicating complex adenovirus (CAdVax) vector platform to develop a RVFV vaccine (Holman et al., 2009). Immunization Route: Intramuscular injection (i.m.)	Vaccine Ontology ID: VO_0004663 Type: Recombinant vector vaccine Status: Research Host Species for Licensed Use: Baboon Host Species as Laboratory Animal Model: lambs Vector: Modified Vaccinia Ankara (MVA) virus vaccine vector Vactor Name: Modified Vaccinia Ankara (MVA) virus vaccine vector VO ID: VO_0001107 Preparation: A modified vaccinia virus Ankara (MVA) vectored vaccine encoding the Rift Valley Fever virus (RVFV) glycoproteins Gn and Gc in lambs (Busquets et al., 2014). Immunization Route: Intramuscular injection (i.m.)
References	References
*Holman et al., 2009:* Holman DH, Penn-Nicholson A, Wang D, Woraratanadharm J, Harr MK, Luo M, Maher EM, Holbrook MR, Dong JY. A complex adenovirus-vectored vaccine against Rift Valley fever virus protects mice against lethal infection in the presence of preexisting vector immunity. Clinical and vaccine immunology : CVI. 2009; 16(11); 1624-1632. [PubMed: 19776190].	*Busquets et al., 2014:* Busquets N, Lorenzo G, López-Gil E, Rivas R, Solanes D, Galindo-Cardiel I, Xavier Abad F, Rodríguez F, Bensaid A, Warimwe G, Gilbert SC, Domingo M, Brun A. Efficacy assessment of an MVA vectored Rift Valley Fever vaccine in lambs. Antiviral research. 2014; ; . [PubMed: 24933081].