|
|
Vaccine Comparison
|
rBCGpMV361-TgCyP |
T. gondii recombinant vaccine vector rBCGpMV361-TgCyP |
| Vaccine Information |
Vaccine Information |
- Vaccine Ontology ID: VO_0004656
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: None
- Host Species as Laboratory Animal Model: mouse
- CyP
gene engineering:
- Type: Recombinant vector construction
- Detailed Gene Information: Click Here.
- Vector:
- Preparation: Following amplification of the T. gondii cyclophilin gene, the shuttle expression plasmid pMV261-TgCyP and integrative expression plasmid pMV361-TgCyP were constructed, and their expression was stimulated after transfection into BCG (Yu et al., 2013).
- Immunization Route: Intramuscular injection (i.m.)
|
- Vaccine Ontology ID: VO_0004602
- Type: Recombinant vector vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Mouse
- Antigen: TgCyP(Yu et al., 2013)
- Vector:
- Vactor Name:
- VO ID: VO_0001023
- Description: Mycobacterium bovis is used as a live vaccine vector. This stdy has shown that a "BCG vector expressing a target antigen, TgCyP, represent an alternative system for the production of effective vaccines to prevent toxoplasmosis" (Yu et al., 2013).
- Vector: BCG
- Immunization Route: Intravenous injection (i.v.)
|
| References |
References |
Yu et al., 2013: Yu Q, Huang X, Gong P, Zhang Q, Li J, Zhang G, Yang J, Li H, Wang N, Zhang X. Protective immunity induced by a recombinant BCG vaccine encoding the cyclophilin gene of Toxoplasma gondii. Vaccine. 2013; ; . [PubMed: 24176493].
|
Yu et al., 2013: Yu Q, Huang X, Gong P, Zhang Q, Li J, Zhang G, Yang J, Li H, Wang N, Zhang X. Protective immunity induced by a recombinant BCG vaccine encoding the cyclophilin gene of Toxoplasma gondii. Vaccine. 2013; ; . [PubMed: 24176493].
|
|
