|
Vaccine Detail
S. pneumoniae pspA-rBCG Vector Vaccine |
Vaccine Information |
- Vaccine Ontology ID: VO_0004601
- Type: Recombinant vector vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Mouse
- Antigen: Pneumococcal surface protein A (PspA) present on all strains of pneumococci (Langermann et al., 1994)
- PspA
gene engineering:
- Type: Recombinant protein preparation
- Detailed Gene Information: Click Here.
- Vector:
- Immunization Route: Intramuscular injection (i.m.)
- Description: Streptococcus pneumoniae is one of the leading causes of bacterial pneumonia and acute otitis media, a type of meningitis. It is becoming increasingly antibiotic resistant and the current available vaccine does not elicit protection in children. (Langermann et al., 1994)
|
References |
Langermann et al., 1994: Langermann S, Palaszynski SR, Burlein JE, Koenig S, Hanson MS, Briles DE, Stover CK. Protective humoral response against pneumococcal infection in mice elicited by recombinant bacille Calmette-Guérin vaccines expressing pneumococcal surface protein A. The Journal of experimental medicine. 1994; 180(6); 2277-2286. [PubMed: 7964500].
|
|