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Vaccine Comparison

T. gondii mic2 mutant vaccine T. gondii OMPDC mutant vaccine T. gondii OMPDC/UP mutant vaccine
Vaccine Information Vaccine Information Vaccine Information
  • Vaccine Ontology ID: VO_0003012
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Mouse
  • mic2 gene engineering:
  • Immunization Route: Intraperitoneal injection (i.p.)
  • Vaccine Ontology ID: VO_0003013
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Mouse
  • OMPDC gene engineering:
    • Type: Gene mutation
    • Description: This OMPDC mutant is from Toxoplasma gondii (Fox and Bzik, 2010).
    • Detailed Gene Information: Click Here.
  • Immunization Route: Intraperitoneal injection (i.p.)
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Mouse
  • OMPDC gene engineering:
    • Type: Recombinant protein preparation
    • Description: This OMPDC/UP mutant is from Toxoplasma gondii (Fox and Bzik, 2010).
    • Detailed Gene Information: Click Here.
  • UP gene engineering:
    • Type: Gene mutation
    • Description: This OMPDC/UP mutant is from Toxoplasma gondii (Fox and Bzik, 2010).
    • Detailed Gene Information: Click Here.
  • Immunization Route: Intraperitoneal injection (i.p.)
References References References
Huynh and Carruthers, 2006: Huynh MH, Carruthers VB. Toxoplasma MIC2 is a major determinant of invasion and virulence. PLoS pathogens. 2006; 2(8); e84. [PubMed: 16933991].
Fox and Bzik, 2010: Fox BA, Bzik DJ. Avirulent uracil auxotrophs based on disruption of orotidine-5'-monophosphate decarboxylase elicit protective immunity to Toxoplasma gondii. Infection and immunity. 2010; 78(9); 3744-3752. [PubMed: 20605980].
Fox and Bzik, 2010: Fox BA, Bzik DJ. Avirulent uracil auxotrophs based on disruption of orotidine-5'-monophosphate decarboxylase elicit protective immunity to Toxoplasma gondii. Infection and immunity. 2010; 78(9); 3744-3752. [PubMed: 20605980].