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Vaccine Detail

VEE Virus PE2/E1 mutant vaccine
Vaccine Information
  • Vaccine Ontology ID: VO_0002996
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Mouse
  • E1 glycoprotein gene engineering:
    • Type: Gene mutation
    • Description: This PE2/E1 mutant is from Venezuelan equine encephalitis virus (Davis et al., 1995).
    • Detailed Gene Information: Click Here.
  • PE2 gene engineering:
    • Type: Gene mutation
    • Description: This PE2/E1 mutant is from Venezuelan equine encephalitis virus (Davis et al., 1995).
    • Detailed Gene Information: Click Here.
  • Immunization Route: intranasal immunization
References
Davis et al., 1995: Davis NL, Brown KW, Greenwald GF, Zajac AJ, Zacny VL, Smith JF, Johnston RE. Attenuated mutants of Venezuelan equine encephalitis virus containing lethal mutations in the PE2 cleavage signal combined with a second-site suppressor mutation in E1. Virology. 1995; 212(1); 102-110. [PubMed: 7676619].