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 Vaccine Comparison
                        
                          
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                              ALVAC-RHDV (vCP309)                               | 
                            
                              rORFV-RHDV-VP60                               | 
                           
                          
                            | Vaccine Information | 
                                                        Vaccine Information | 
                                                       
                          
                            
							
                              - Vaccine Ontology ID: VO_0004738
 
                              - Type: Recombinant vector vaccine
 
                              - Status: Research
 
                              - Host Species for Licensed Use: Baboon
 
                          - Vector: ALVAC vaccine vector
                            
						
 
                                            - Preparation: An ALVAC (canarypox)-based recombinant virus ALVAC-RHDV (vCP309) expressing a native rabbit hemorrhagic disease virus (RHDV) capsid protein was derived and assessed for its protective efficacy in rabbits (Fischer et al., 1997).
 
                              - Immunization Route: Intramuscular injection (i.m.)
 
							 
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                              - Vaccine Ontology ID: VO_0004767
 
                              - Type: Recombinant vector vaccine
 
                              - Status: Research
 
                              - Host Species for Licensed Use: Rabbit
 
                          - ORF1
                            gene engineering:                            
                            
                              - Type: Recombinant protein preparation
 
                              - Description: Recombinant Orf virus (ORFV; Parapoxvirus) expressing the major capsid protein VP1 (VP60) of the calicivirus, rabbit hemorrhagic disease virus (RHDV) (Rohde et al., 2011).
 
                              - Detailed Gene Information: Click Here.
 
                             
						 
                          - Vector: ORF virus vaccine vector
                            
						
 
                                            - Preparation: (Rohde et al., 2011)  Anew recombinant Orf virus (ORFV; Parapoxvirus) expressing the major capsid protein VP1 (VP60) of RHDV.
 
                              - Immunization Route: Intramuscular injection (i.m.)
 
							 
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                  | References  | 
                                    References  | 
                                   
						  
                            
							                                                                Fischer et al., 1997: Fischer L, Le Gros FX, Mason PW, Paoletti E. A recombinant canarypox virus protects rabbits against a lethal rabbit hemorrhagic disease virus (RHDV) challenge. Vaccine. 1997; 15(1); 90-96. [PubMed: 9041672]. 
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							                                                                Rohde et al., 2011: Rohde J, Schirrmeier H, Granzow H, Rziha HJ. A new recombinant Orf virus (ORFV, Parapoxvirus) protects rabbits against lethal infection with rabbit hemorrhagic disease virus (RHDV). Vaccine. 2011; 29(49); 9256-9264. [PubMed: 22001119]. 
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