- Vaccine Ontology ID: VO_0004715
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Mouse
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gene engineering:
- Type: Recombinant vector construction
- Detailed Gene Information: Click Here.
- Vector: Lactobacillus gasseri vaccine vector
- Preparation: Targeted B. anthracis protective antigen (PA) genetically fused to a DC-binding peptide (DCpep) was delivered by Lactobacillus acidophilus (Mohamadzadeh et al., 2010)
- Immunization Route: Intramuscular injection (i.m.)
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- Vaccine Ontology ID: VO_0004702
- Type: Recombinant vector vaccine
- Status: Research
- Host Species for Licensed Use: Mouse
- Vector: Salmonella typhi vaccine vector
- Preparation: Anthrax protective antigen was delivered by Salmonella enterica serovar Typhi Ty21a (Osorio et al., 2009)
- Immunization Route: Intramuscular injection (i.m.)
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Mohamadzadeh et al., 2010: Mohamadzadeh M, Durmaz E, Zadeh M, Pakanati KC, Gramarossa M, Cohran V, Klaenhammer TR. Targeted expression of anthrax protective antigen by Lactobacillus gasseri as an anthrax vaccine. Future microbiology. 2010; 5(8); 1289-1296. [PubMed: 20722604].
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Osorio et al., 2009: Osorio M, Wu Y, Singh S, Merkel TJ, Bhattacharyya S, Blake MS, Kopecko DJ. Anthrax protective antigen delivered by Salmonella enterica serovar Typhi Ty21a protects mice from a lethal anthrax spore challenge. Infection and immunity. 2009; 77(4); 1475-1482. [PubMed: 19179420].
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