Vaxvec

Vaccine Detail

SL3261 expressing streptococcal M protein

Vaccine Information

Vaccine Ontology ID: VO_0004676
Type: Recombinant vector vaccine
Status: Research
Host Species for Licensed Use: Baboon
Vector:
- Vactor Name:
- VO ID: VO_0001031
Preparation: The aroA strain of S. typhimurium SL3261 was transformed with a low-copy plasmid vector pMK207, which contains the cloned gene spm5 encoding streptococcal M protein, the major virulence factor of these organisms (Poirier et al., 1988).
Immunization Route: Intramuscular injection (i.m.)

References

Poirier et al., 1988: Poirier TP, Kehoe MA, Beachey EH. Protective immunity evoked by oral administration of attenuated aroA Salmonella typhimurium expressing cloned streptococcal M protein. The Journal of experimental medicine. 1988; 168(1); 25-32. [PubMed: 3294331].