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VR2210 DNA vaccine plasmid

DNA Vaccine Plasmid ID 109
DNA Vaccine Plasmid Name VR2210 DNA vaccine plasmid
Plasmid VO ID VO_0005023
Promoter Names CMV
Antibiotics Resistant Gene kanamycin
Plasmid Description Constructed by the molecular ligation of three purified DNA fragments: PstI/XbaI-digested VR1012 plasmid DNA; PstI/KpnI-digested DNA fragment from the human tissue plasminogen activator (hTPA) gene, including a portion (113 bp) of the 5 ' -untranslated region proximal to and including the leader peptide (aa 1-23); and KpnI/XbaI-digested DNA encoding aa 17- 273 of the B31 ospA gene (Luke et al., 1997)
Related Vaccine(s)
References
Luke et al., 1997: Luke CJ, Carner K, Liang X, Barbour AG. An OspA-based DNA vaccine protects mice against infection with Borrelia burgdorferi. The Journal of infectious diseases. 1997; 175(1); 91-97. [PubMed: 8985201].