- Vaccine Ontology ID: VO_0002952
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Pig
- E(rns)
gene engineering:
- Type: Gene mutation
- Description: This E(rns) mutant is from Classical swine fever virus (Sainz et al., 2008).
- Detailed Gene Information: Click Here.
- Immunization Route: intranasal immunization
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- Vaccine Ontology ID: VO_0002953
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Pig
- E1
gene engineering:
- Immunization Route: intranasal immunization
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- Vaccine Ontology ID: VO_0002954
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Pig
- E2
gene engineering:
- Type: Gene mutation
- Description: This E2 mutant is from Classical swine fever virus (Maurer et al., 2005).
- Detailed Gene Information: Click Here.
- Immunization Route: Oronasal immunization
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Sainz et al., 2008: Sainz IF, Holinka LG, Lu Z, Risatti GR, Borca MV. Removal of a N-linked glycosylation site of classical swine fever virus strain Brescia Erns glycoprotein affects virulence in swine. Virology. 2008; 370(1); 122-129. [PubMed: 17904607].
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Fernandez-Sainz et al., 2009: Fernandez-Sainz I, Holinka LG, Gavrilov BK, Prarat MV, Gladue D, Lu Z, Jia W, Risatti GR, Borca MV. Alteration of the N-linked glycosylation condition in E1 glycoprotein of Classical Swine Fever Virus strain Brescia alters virulence in swine. Virology. 2009; 386(1); 210-216. [PubMed: 19203774].
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Maurer et al., 2005: Maurer R, Stettler P, Ruggli N, Hofmann MA, Tratschin JD. Oronasal vaccination with classical swine fever virus (CSFV) replicon particles with either partial or complete deletion of the E2 gene induces partial protection against lethal challenge with highly virulent CSFV. Vaccine. 2005; 23(25); 3318-3328. [PubMed: 15837238].
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