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Vaccine Detail

Leishmania donovani cen1 mutant vaccine

Vaccine Information

Vaccine Ontology ID: VO_0003005
Type: Live, attenuated vaccine
Status: Research
Host Species as Laboratory Animal Model: Mouse, hamster
cen1 gene engineering:
- Type: Gene mutation
- Description: This cen1 mutant is from Leishmania donovani (Selvapandiyan et al., 2009).
- Detailed Gene Information: Click Here.
Immunization Route: Intravenous injection (i.v.)

References

Selvapandiyan et al., 2009: Selvapandiyan A, Dey R, Nylen S, Duncan R, Sacks D, Nakhasi HL. Intracellular replication-deficient Leishmania donovani induces long lasting protective immunity against visceral leishmaniasis. Journal of immunology (Baltimore, Md. : 1950). 2009; 183(3); 1813-1820. [PubMed: 19592661].