|
|
| Record Information |
| Record ID |
46 |
| Pubmed ID |
31320597 |
| SNP |
|
| Gene ID |
3598 |
| Protein ID |
Q14627 |
| Vaccine Adverse Events |
fatigue, convulsions, and nausea |
| Vaccine |
Dendritic Cell Vaccine ICT-107 |
| Gene Name |
IL13RA2 |
| Official Symbol |
interleukin 13 receptor subunit alpha 2 [Homo sapiens (human)] |
| Aliases |
CD213A2, CT19, IL-13R, IL13BP |
| Other Designations |
interleukin-13 receptor subunit alpha-2; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2; cancer/testis antigen 19; interleukin 13 binding protein; interleukin 13 receptor alpha 2 chain; interleukin 13 receptor, alpha 2 |
| Chromosome |
X |
| Location |
Xq23 |
| Annotation |
Chromosome X NC_000023.11 (115003982..115017616, complement) |
| MIM |
300130 |
| DNA Sequence |
>NC_000023.11:115003982-115017616 Homo sapiens chromosome X, GRCh38.p14 Primary Assembly
TTCGCAAGAAAAATTCAGTTTATTGAGACTCATATTGAACATTTGGCCATGACTGGAAACTGTTGAGTCA
ATACCATGTCTCTTGATATGGAAAGTCTTCATGTATCACAGAAAAATTCTGGAATCTAGAAAGAACTCTG
TTATTAACAAGTCATCTCTAATAACACAAACTATTTCACTGAAGATTAACAACTCAGAGAATAAGCACAA
GAGCATTCAGCAAACAAAGTGAAGCATTCTATACACATTCACTTTTCTCTCTATCTTGAAAAGATATGGC
ATTGAGATATCTTTTCTCAGCTGGGCACAGTTGCTGGCACCTGTAATCCCAGCACTTTGGGAGGCCAAAG
TGGGAGGAATTGCTTGAGCCCAGGAGTTTGAGACCAGCCTGGGCAACATAGCGGGACTCCATCTCTATAA
AAAATCTAAACATTAGCCATTGTGTCTGGCTAATGTTTAAATTTTTTATAGAGATGGAGTCCCGCTATGT
TGGTGCCTGCCTGTAGTCCCAGCTACCCAGGAGGCTGAGGCAGGAGGATTGCTTGAGCCCTAGATACCAA
GGCTGCAGTGAACCATGATTGCACCACTCCTCTCCAGCCTGAGTGACAGAATGAGACCCTGTCCCAAAAA
GATATTTTTCTCCAGGTTACAACTCCTCCTTAAAGCCCCCCAACCCAGAGTGGTCCTATTGTTTTCTGAA
ATTCTATAGCATTATCTGCACGACTCAAATGGCAATCATCTAAAATCATCTCAAAGGTTATATTTTTTTG
TATGGATCCTGTCTCCCTTAACTTGAGTGTGTGCTCCAAAGGCAGGCACCATGCTTTATCATTTGCATGT
GTTCTTGTGCCTGTGGCACACTGGTAATATGTGTTTCAGTCTATGATCATTTTAATTCACTCTTCTATTT
CTCCCAATCCTGCTTTTCTCTTGTAACTCTTTCCGTATACCATTCTCTAATCTAGGGCCAAATAGTATTT
CATGTTTAAAGTTTGATTTCGACAAAAGTAAATCCACCTCAAAATGAAGTCTTGTAAGCTTAATTTTTAA
AAATTGCTGTATTTTCTGAAGATAACATCATAATCCATACGGAATCAATTGTACACCCACAGCGAACAAG
CAAAATTATAAAATGTATCTCCATCAGTTCTAAGTGCAGAACATTTTAAAAATCTCCTATTCTCAGGCTA
AACATCATAATGTTACACATCTTACCATTTTTGGGTAGGTGTTTGGCTTACGCAAAAGCAGACCGGTTAC
AAATATAACTAATATTAAGATGAAACCAAATGGTAGCCAGAAACGTAGCAAAGTTTTCTTCGATAGGTCT
TCACCTAGGATTAAAAATCACACGGAAAGGGGAAGTGTTAGACATTTGCCACTATTTTTGAAACTGAATT
ATTTTATAAATACTTCAGAACTGAGTTGAGCTTGGAAACCCCTGTCATATTTGCCAGTGCATAAATACCA
CAATTGTGTTTGAGTATAGCGTTCCTTTCATTTGTGCAATTTTTATATAGAAAAGTACTTTACTGAACTG
TGACATGTCTTATTTTCACTTAGAAAAATAACTTCCCCAAACACAATTCTTATTTCCTGATATGAGTTTG
TTTATATTTGACCTTGTGAATTCTCCATTTAAAAATGACAAAATATTAGCCAAGTGATTAAACAAACATG
TCCTGTGTGTCTGTCTCTTAACTCTCAGTAAGTCAAACGTGTACTTAGATCATAGGATACTGTACCAAGC
AAGAGGTATCCTTCAATAAAAATTCCTGTGTGAGTAATGGAAATCATCTTTTAAGGTTACCTTTTTAAAG
TTGTCTCATATTTTAAAGACCAAAGGGAGGGATAAGGTTTTTCTTTTCTTTTTGATTTTGCTTTGTTAGT
TTAGGGATGGAGTTTTAATGGTTCTTCTGCATAGCAAGAAATGAGCAATCACTAGGCAAACTTAAAAAGC
AGACGAAGTTTGGTCTCCCTAAACTAGTACCTCTCACTTGTTTTGGAGTAATATAAAAGATCTTGAATCT
TAGCCACGCATCTACAAAGCTCTCTTGATCCCACCTTTTTCTTTGTCCTATTTCCTCACGATCTTGTTTT
CTATTAGAAAATTATCAGTCAAATTCACGTGTTCAGAGAAGATTTACAAGAATATAATCCAGAGAAATTA
CTGATGTAAGTTATCTGTCATGCAAAATTAACAGTGGGAAGGCAGGAAGCTCCTTTGCTGAAGTTCTACT
GGCTTTCCCCATACAGAGTCAATCCTGAAGAGGACATACTTTTATTTCCAAAAATATTATTGTCCTATTT
TTCTATAACTTGAAACATCCAATAAGAAATGTCCTAAAGAACTGAGACCACATGCAACTCAAGAAATTCC
TTGTTTCTAATTTCAAAGTCATTAAGATTCTATGAAGAGGGCTGGGCACAGTGGCTCATGCCTGTAATCT
CAACACTTTGTGAGACCGAGGTGGACGGATCACTTGAGGCCAGGAGTTCAAGACCAGCCTAGCCGACACG
GTGAAACTCTGTCTCTACTAAAAATACAGAAATTAGCCAGGCGTGGTGGTGCATGCCCGTAATCCCAGCT
ACTCAGGAGGCTGAGGCACGAGAATCGCTTGAACCCAAGAGGCAGAGGTGACAGAGAGCCAACATCATGC
CACTGCACTCCAGCCTGGGTGATAGAGCAAGACTCTGTACCAAAAAAAGGAAAAGATTTCCCTCAAAGCA
AGAGAAATCTTAGGCATCACTATCATTGATAAGATTGCATGTAAAATACAGAAAAGAATATATTTTTTGA
GGATATGGCTAAAAACTCACCATAACCACTTTATACAATGCATTGACTAATGACGAGATATAGTTCAGGA
CATAACTTTAGAGTTTCCTGATTTTTTAAAACAGTAACAAAAATGAAAAACATAAAACTAGTAAGTCTTC
TTTCTGATTCCATATAGCTCTTGGTTGAGTTTTCCACTGTCTTGCTATTTTTTCTCCATAATCCTTAGTG
ATTATATAATCTATTAGGCTTCTCGTTTATTGCCTATCTCTACCCAATTGGAAATAAAATGTAAGTTCAC
TGAGGGTAGAGATTTCTTTACTGCCATATCTGTAATGCTTGAAAAGAGTCTGATACATAGTAGGTGCTTA
ATAAATATTTGATGAATGAAAGGGATCAATGATACCACTGTATTCGTAGGGAGATAATAGAGATTCCACT
ATAGTAGAACAACATGAAAGGAGATGAATGATTGATAGATATGGCAGTATCTGTCTGTATCAGCATCAGT
ATATTTATTTAGAGCTGCATCTATATCTATGTACCTGAAAGAGCAATGCTGAGTTGATTTCCTTCAATTT
TGAACATTTATTAGTAATTTCTACTCTTAAAGCTAATACATTGTGAAGCACAATCACATTTTACCTCATT
CTTTAGGCTTTTTAGTTTATATTGCTATGTAATTTAAATGACTTTATCACAAATCACTTTAAATCAGTGT
TAGAAGTGAATGGAATGAATATGTATTTTACTATTCATGACCTTTTAATTAGAAAAATATTCCTTTTGAA
TAGTATTAGACACCCAGAAACAAATGTATGCTGATCTATACTTGCTTTAAGATTTCTGTTCTCTTGAATA
CTGAAAGCATATGAAAATATTGATTAAAATAAGTTCCTGCCAATCTCTCAAAAGAATGAGCATATTATCT
ATATTGACAGAAAAACAAGAATTTTGATAATAGAAGTATAACAATATTCCTAGTCCTAACTGAATGAATA
TTAGACTTTTAATAAATCTTTATTCAATTGAAGTGCTCCCTAACTTATTCTCTCTGTTCATAGACTATAT
GGGAAAGTCCTTCACTTCTGTAATTACAAAATACACCAAAAGAAAATTAATTTTGCTAGCAAAGAGCTCA
TTATTTAGTTACTGTCCTTTTAGCTCATACCTTCCCAGCATTGTTTATCACTCCACTCACTCCAAATTCC
GTCATCTGAGCAATAAATATTCACTTTGCTTCTTACTACAAAGCATAATTGTCGGGTTTCATTTGTTGTT
TTCAAGGTGTATGTTTCATTTTCAACTGTAGCAGTCTGAAAGCCAAGGACAAAATCAGATGCCATTATTT
GATCTAGTTGCAACTAGACAGATTCCATATCTGTCCCTTTCAAAGTGGGTTTTATTACATAAAATCTATG
CAATCTATGCATCAAAAGACTGGATGCATAATCCCAGCAGTAATTAGCTCTCTGTATAGTGGGGGTTTTA
AAATCATTGTTTCTTCCCTTCTTTATCTATATTTTATTTCTACAGTGATAATGGATCACTTACAGTGAAG
GACAGCATGTGTGAGACAGCAAAATTCCTAGGTAGCCTTGGTGTTTATAACACCCAGTATGTGGACTAGT
GTCAAATTTCCCAGATTCTATGAACTGGAAGATGCTACATACACTCAGTTACCAAAAGACAGAGCCAGCA
TGTGAATGTTATTACTATGGAAACTATAGAGTTCACATATTAATATATAGCTTTTTCTTTTTTCCTTATG
CTTATTTCCTTATTCTGATTGTTAATAAGAATAAGGAAAACCTACATAACAATGCTCAGGGCTTGGAATA
AGAATAAGGAAACAAAACCTGTATAACAGTGCTCATGGCTTGGTATGAAACTATTGCTACAGTTATGAGA
CTATCTCAAGGCTGGGTGATCTCAGAGTAAAAAAATCACTGAAGCAATTATTTCAATTTTGCATTTCAAA
GAGCTGAAGAATTTTTCTCATTCAATATAATAGCTTTTCCTTTGGCATAACTTATCTTAGGAATCAACAT
AATGTAGTGTAGACTTAAGTGGACTGGGAACCAGATCTGATATCTAGTTCTAGCTGCATAATTTGATTGT
AAGTGAATTTACATACCTGGGATCTATACATCAATTCAACAACCAGTTTTCTTATCTGTATATGAAAGGA
ATGAATTAGAACTACTGACTCACTAACTTCTCTCTACCACTCTCTAAACTGGAAACTAATAAGGAAAAAT
AATATATAACAATGTGTGATTAAAGGCATCACCACATTGTTGGTGCTGGTGGCAGTAATTAGTCTTGCAA
CCATTGCCTAATTCCCCAGGCAGCCCTTCTTGCCTGGTACAAGCAATTCTCTTGTAAGCCTGCCATACTG
TAATTTTGACCTGATGGTTGTTCCTCAATAAGTGGTCTTTGTGGGTTTTTTTTTTTAATTTTGTTTTGCT
TTTACTTGAGGCCTCTCCACAATCCATCTTAAGCCTTCACCAACTTTAATTTATTGACACAAAATTGAAA
ACAAGTGACTAGATAATCTCTAAGGTCCTATGTAACTTTAAAATTGGTATCATTCATTATACTTTTGTCC
ATTAGCTTATTTGGCTTTCTGGAAATTGAACTAAGATATATGTCATGTTCTGTCCCTCACGTGGATGCAA
CTGATTTTGGTTCTCACATTTGCTATTTTATTTAAAAGGCTGTAGTTATGATTTTCCCAAATAAATGCAA
TATTCATACCACCAAGGTAGTATCATCTTCTCTGATCTCAATTTCATAATCAAAACACCTTGCTGGAATA
GGTCCCAAAGGTATGCTCCATTTCAGCTTAATTTCACATGAACTCTCCCGAGTAAAAGTAAGATAGACTG
GCGGCAAAGGTTTAACTGAAAAGCAAAAGAGAACCATTTCAACACGGAGATTGTTGAAGTTTAGCAGTAG
CCTTTATCCAAAGCTAGGGACATCTGGTAACAGAAACCTCCAGGGATAAACCAAGTGGCTCAGTAATATT
CCCTATGATACGTATTAAAATCAAAGTTGCTTGCCAACCAAGATGAGTTTATTAACAAACTTGGTTATTT
TGGAAACTCATTTTTGACAAGTCACCCACTGACAAATATATAAATCCAAGAGAAAAGTTCGAAGACCCAA
ATCATTACAACAATTTTCCATTTTGTAGCATTAGAAATAACAACCACAATCAACAATACTACTACTTTTA
CAAATAGATAACCCTATTTAGTGCTTATGCTATTTCAGACACTGTAAGTACCAAGGATGTTACATAATAA
TCTCATTCACGCCTCACAATAAACCTATCAGGTGGTCCTCTGTTATCCTCATGTTACTACTAAGGAAATT
GAAACAGAGTAACTTGCCCAAAGTCACACGACTAGAAAAATGGTAGATCTAAGATTTAAACCCAGGTCTG
GCAGACTCTAGAACCCATCACTCTCATAACCATTAGAACTGAAAATATAGACTCAATAAATATCCAGCCA
TTTGTCTATTGAGGCCTGGGAAGAAGTATCTTCATAATTAATCCATCACTAACACTAGACAAAAGTACTG
TATAGCAGACAAACTGAAGATGGAAAATAAAATTGTGAGTTCTAAATGAAAATGATACTTTAACCTTTAT
TAAATTTCTTATCTTTCATCCTTAAATATTTAATAAGCGCCACCTCATACACTCTGCTGACTCTCATTTT
TCTGTCTTTGCATTTCCATAGGTCTCTGTCTCTCTCTCTGTCTATGTCTCTCTCTCCTTCCTCCCCTTTT
TCTCTCTCTCACCCTCTCAAGTGGTTGTAAATGGCCTAAACTAGAAACAATGAATTTGAAGTTGTTTGTT
GGTTTACATCACCTATATTTTGAAGCTGAAAAGTGAAATAACTGGATCTGATAGGCTTGTTCTCTGATGA
TCCATTAACACAAATATAGAAATCTTTATAGTCTGATGCCTCCAAATAGGGAAATCTGCATCCTATATTT
TGTCCATCAGCCTTGATGTAATCAACACACTGTAATGCATGATCCAAGCCCTCATACCTGTAAAATGAGT
GTTGTGAGAATTGTGTTTAAATAACAATCTTTTCCAGTATCAAGGCACTTCATTTTCAATTATATTAGGA
TACCATGTCAGTTTAAAAATCATTTAATAATGTACAATATTTATTAAGCACCTACTATATGTCAGGCACT
ATGATAAGCAATAGGGAAAAAACAGTAGGGAAAGCAGACATAGTCCCCGATTTCATGGAGCTTACAATTT
GTTGGGAGTCCTCGCAAAATCTCAAAGACAAGGATTCTTACTTGTGTACTTAGGTTATATTGATTCATCA
ACAAGGTTTGTGAATCAAAGAATAAGATTCCTAGTAAGAAAACCTGTGATTTGTACAAATAATCCTGCAT
GATATTGCCTTTTAAGTTATTTTACTGGGGAAGTTATTTTAAAAGAAAGCAAATTTTAAAGCAGACTTAG
AAAATATTATGTTTAATAAAATGAATGAAAATCTGGAGTATACAATACACATCAAGAGATAAACCTCAGA
AAAGCCAACTGTAGGAGGGCAAAAGGAAAAAGAAGGAGTTGTTTGGCAAGTAAATATTTAATTTTCTCAT
CTATTAAATGAGAAATGTTACCATATCATTTTAAGTTAACCTTATTCCAGTAATAAAGCTAAAAGGAACT
AGGAGTGATTCCCTACTAAATTCGAAAGCAACAAATGCTTGCTATTTTCCTAAAGAATAGCTTGCAATGC
AAACCATGACATTATCTGTAAAAGCAGTCAAATCCCTGTTGAAAAGAGGCCAATGTAGCAGCTGATAAGG
TGCCTGTACACATATCTGGACTCTACTAAATTAACCTTATGCCAACTATTTACTTTAGGGAGAGTTTGCA
AAATTGTTGTCTCTTGGTTAGTTCACTTGATTAGAGTTTGGGAGACTTCAGTTCCAGGCTTAACTCCATA
CAGACTTACTTGATGTCAGCAGGGAAGGCTTTATTTTCCAATCTCTAAAATGTTAATGTTTATTCCTCCC
TATTTCACCAAGATGAGGATCAAATTATATCAAATATGAACCACAATGTACAGGAGGGCAGAGACTTTCT
CTTATTCATGCTTTTGTCCTTTTTATCTAGAACACTGCCTGGCATTTAAAAGATGCTTAATATTTGTTGA
ATTAATGAACAAATAATTTAGATCTTTGAAATTTACCTATCCAATTCCAGATGAGGAAACAAAAATTCTA
AAAGAAAAAATTACTTGCCCAAGGCCGCCAAGTTAAATGATGCTAGAGCAGGGATTAGAACCCAGATCTC
AGGATTGTTAATAGTTTATAGCTTATGATTTATCTATTATTATTTTCTAAAGAAAGATGCCATGATAATT
TGGAACTAGAACTCACCAATAGTAATGCTTAGTCCTCTCTTGATTTTTCCATTATTTAGTAAATGCATAT
GTTTGGATAATTACCTATCAGTTTATCAGTGCTATCACTTGTTTCAGCTATGTAATAAATATTTAGTGCT
AATCTACTACGGGTATAGTACTTTGGAGGTAGGCAAGAGAAATATAATAAACAATTCATGCCCACCAATC
CCTTAAAAATTTAACAGGAGACAAAGCACACATATATGAGAAAAAATTTAAATGCCATCTGGACAATAAA
CAATTACAGGCTATAAAAAAAAATAGTTCAAGGCCAGGCGCAGTGGCTCACGCCTGTAATCTCAGCGCTT
TCGGAGGCTGAGGTGGGCAGATCACTTGAGGTAAGGAGCTTGAGACCAGCATGGGCAACATTGTGAAACC
CCATCTCTACTAAAAATGCAAAAGTTAGCCAGGTGTGGTGGCACACGCCCATAATCCCAGCTGCTCGGGA
GGCTGAGGCATGAGAATCGCTTGAACCCAGGAGGTGGAGGCTGCAGTGAGCCGAGATGGCACCACTGCAC
TCCAGCCTGTGTGACAGAGGGAGACTCTTGTCTCAAACAAACAAACAAAAAAAAAAACAAAGTAATAGCT
CAAGAAAAACAAAACAGAAGCTGACATGATCAGTTAAAGGTTAATGAAACTGGGGAGCAGATGAGCCTTG
AAAAAGATGGATAAAAATTGGTGAAAGAAAGATAGAGCCAGAGGGCATTCCAGAAGGTAATGCAAACAAA
GGTATAAAAGGCAATAACACGGGTGAGAAAAAAATGTAGAGATGGATCTAAATTGAGTGGAGCATTCACA
TTGGTAATAGTAGACAGTATGGCAGCCTAGATTTTATCCTGGGGCAATGAGTAGACACAGGAGGTTTTTG
AACAAGAGAGTGGTATATGAAAATGGCAATATAGGAAGATAAAGCTGGCTACAGTGTGCAGAATGAATAA
AAAGGGGAGAGATTGGAAGGGGAGAGATTGGGAGCAGAGCGACCGTCATTTTGGAAGCAATGGCAATCAT
CCAGGTGTGGAATGAGGGAAGCCTAAAGTAGAGCTCTTACAGTAGAGATGGTAGGTACTTAACAGATGTG
CAACCTTGCAAAGGAGCATCAGAACATGGTGATCATGTTACCCTAAAACAATTAAGAAATTAAGAAGATA
CACGAGTCACAATGTCCAAGTTTAAAAGCTTCAGTGACAGTTAACAAAGGAGGGAGTCAGAAAAAAATTC
AGTTTAATAGATAACTGATTTTTTAAAAAAACAAGAATATAAAATATGTCAAAATTGTTTAAGTTCTAAA
TTCATCTATCTAAAGGATACAAAATTAACCCAGTACAGAAACAATTATTGCATTCCTTATATCACCCATA
GAATACCTTCCAGTATCTACATCCTAAAACCACTTACACCCATTGAAAACCTCAAATAATTGTAAACAAT
TATCATCATAAATACAACTCTGACAAGTATAATGAATTTAACTTAGTGAAAATATAGTTTACTCATACTA
TCGACTAACTTGAGTAGACATTTTTTAATATGGAATTCTAATTATAAAAATACTTACCAGTAAAACAAGT
TGTAATTGGTATCAAGAAGTACACCTATGCCAGGTTTCCAAGAACAGAGTAAATATTGCCAATTGTAATA
TACGCAATCCATATCCTGAACTTTAGTTTCTGGAATTCCTAAGGAACAAATCAACTGTGAATGTTTGAAA
GGCTTGGTGATGAATCATTTGTGAAATCATTTCTCAATTTTACTTCATTTCCTATGACCTCTCCATTTTA
TTTTGCAATCAACATAACAGGATTATTTCAAAAGGAAGTTACTGGGAATCACTTCACGATAAGAGGGACA
TGCAAAACCAAAAAACATTTGAGGGCTCATTTACTCATATTAGTATAAGCATATGCAAAAGTAGTAAATT
GATTATTCTAGGATGCTCTGAGCAGATGAGCAAATACTCATGAATGTTTACTAATATGACCCCAAAACTG
GGAACTAAATCAATAAAATAATATACAGGTTTTGCCAAAGGTATTTGCTGATTTAAAGAATTTTAAAAGG
CTAATCACCAACTACAAGAAAGATTCTATTTTGTGCCACACTGTCACAGGATCTATTGTGCCTACAGCCT
GGTACATAAGATTAAGGGACTTATTCCCAAATGAATTGTTCTGATAGTATTAAATATGAAAAGAGAGCTT
TGTTTTAACCTTGTGGTGATATCCAATAAGTAGTTTCTGCCCAGGAACTTTGAACTTCTGATCCATTTGT
GCATTGCCATGGTAAAAGCGTGTGTATCTTCGCTTCAATGCCCTTGTTAAGATCAAACCCATCTTTGTAA
TGTAGATTCTTAGTAATGATGGTCTGTTTGACAAAAAGATGAGACAAAGTCAAGCTTAGAAACCTCCATG
GTATAGTGAGCTATATTAATAAGACTAATAAATCATTAATACCCTGGAGAGTTCCCAATATCTAAGACAA
TCCTAGAGACTATTTGATACAATGCCACAGATACATTTCCAGCAGAGCTCACCTCTGTATGTCATATCAT
TTTATGAGATCATTTGAATCTTAACATCTAATTCCAAATAAAAACAAAAACTTTTGGAAGGGAAAAAAAA
CTTTATGGCAGAAACTTGAGCTATATCTGCTTGGAATCAAATAGATAATTTTCATATACCATAGGCACAT
TACTTGGCAAATCATGCCACATTTCAAAATATAATATGAAACCTTCAAGAAATACATAAACTAAAACCCT
GGAAGTAACCAGAAAAATACAGACAAATCATGAGCTTCTGGAGGACAAAAATCATTTATTATTTATTCAT
ATATTCCTGATACCTAGTAGAGTGCCCAGCACAAAGTTGATCAATAAATGCTCAATTTGAATTGTCTCTT
GAAACTACCTAGCTGAATTAGAGAGGTAACAGAATGTCATCTACAACAGAAATCTTTGAATATACATGCT
TGTTGAGTATATAAGTAGTTAATAATTCAAAACATTTTCATTGAGCTCTTACTACAATATATACAACGAA
CCATAATCCTGCGACCCTCTGTGGGAAGGGTACAAAGATAAATAAGCCTTGTCTCCTACAGTAGAAAAGG
TCACAGGTCAGTAGCATGTATAAGGCCCACATCCAAGAATATAAGCAATTGTAAAATACAGTGAAATGCT
CTTCTAGTGAAGTGCTGCTCTTCAAGTTCATATTGCACGAGACCGAGTTTTTTGTTTTTGTTTTTGTTTT
TTTTCTTGTTCTTCCAATGGCAATCTTAACACTGGATGGGGTGAAAACAGATATAGCAGGATGCATAGGA
GACAGAAGCGGGTGTGGAAGCTTTTTATATCCTAATTAGAACTATTGAGATATGGGAATTGGAGCGGACA
CTAAAGTCAGGAATCACAAAGTAACACCTGATGATCACTCTGATACGGCAAATGCATGCTTTACTTACCT
TCCATGTTTCACTACCAATGTTTCGGTATTTTAGTTCATATTCCACTGTGCATTCCTTAAAATGATCCAG
AGACAGTGGGGGTTGCCATTGCAAATAGAGATAACCTAAGTATCCGGGATCCACTATCTCAAAATCCTGA
GGAGGGTTAACTGAAATAAATCAATAAAACACTTTTATTTTTTCTGTATTTTATGACAAATATTGCTAAA
TCTAGATGGCTTCCAAATGTGCACCAATTGATTAACAGATAAACAAAATGTGCTACATGCATACAATCAA
ATATTATTCAGCCATAAAAAGACATGAAGTACTGATTCATGCTACAACATGGATGAACCTTGAGAACATT
ATACTAACTGAAAGAAGCCAGACACAAAAGACCACATATTGACATAGTTCCATTTCTATGAAATTTCAAA
ATAGACAAATTCATAGAGAGAGAAAGTAGATTCGTGGTTGGTAGGGGCTGGAGGGAGAAACAATGCAGGG
TGACTGCTTAATGGGTTTAGGGGCTGTTTTACGGGTGATGCAACTATTCTGGACTTTGATAGTGGTGATT
GTTGCACAACTTTGTGAATATACTAAAAACCAACGTATAGTAAAGAGTTTTACTATACATGTATAGTTTT
AAAGAATATAGTTTTGTATAAAGAGTTAGTTTTGTGTAAATTATATCTCAGTAAGGCTGTTAAAAAAATC
TAGATTACTGCTATATAGTTGTTCCTTCTTTGAGAAATCACATATGCAAAATGTGACTTTGCCTCACTAG
GTATTAATTTTTAGAGAAGCAAAAAATTCAATGTGGCTTTATCTCTGTGCTCATGTACGCCAGAATTTGG
TCTAAGATGGGAACATTTTATTACAAAAATCTGTCTAACAATAACAATAACAAATAAGAACAACAAATAA
TAACAAATAATAACTAACATATCACTATAATATAAATATATGTATTTAATTATATTAATTATAATATAAT
ATATAATATAATAATATACTATAAATAATTTTAATTAATTAATAATAAAACATTAACATTATATTAAATA
ATATAATATAATTGAAAAATTAAATAATTCTAATTATTTTTAAATTTTACGTTAAATTTCTGTACCTTTT
TAATGTATCTAATTGTCATAAAAGCTAAGGATAGTAGCTAAGGATAGTAATTAAGGAACTGTTCCAGTTA
GTTTAGTACCAGGCAATGAGGTTTCAGATACTTAATCTGTTAAAAAAGACTATACAAAAAGGTATGGAGA
GTGTTTTTAATTTGGCATTTATCGCACAAAATGTGTGTCAACATCAGTTACCTTATACAAGAAAGTGACT
AGTAAGAACATAGCTTTTTTTCATGAACTTCCTGAAATAGTTTCAATAACAATTCATCTACTAGTTAGTT
ATGCACTTCCATAAGGCAGGTCAAAAAGACAGTTAATTTTCCATTAAAATCCATTTAATTTTACTTTTCC
TAATTTAAAAACTATTCCATTAAAATCCATTTACCTTTTATCTCGGTGTCTGAAGATGAAGTACAGCCAA
ATGTTGTGCTTATCAGAAAGGTATATAAGCATCCGATAGCCAAGCAAACGAAAGCCATTTCTCCGAGATT
TAAAACCTTGATATTGCCTCTCTATGAAGGAAAAATATAACATTTTAACTTTATCTTACATCAAATAATC
AAACTAAACGTGATTAAAAATACTTTGGAAAGCTCTCTGTGTGCTTCTCTACCAAGAACTGGGAAAACTG
TGTCCACCTCAGACCATGGAAACAGAAATAATCAAGTTAGGAACCAATATAATTGGAAAGAAAGGATTCT
AGTCTCATCCTGCTTACAAGAATAAAAACAAAGCTAAGCAAAAACCCTTGTAGCTCCTCACCTCCCCGCC
GACAGGCACACTTCTGACCAGGTTATGGCGACTTCAAATAGCCTTCATCCGGAAG
|
| Protein Name |
I13R2_HUMAN |
| Length |
380 |
| Moltype |
AA |
| Topology |
linear |
| Division |
PRI |
| Update Date |
12-OCT-2022 |
| Create Date |
01-NOV-1997 |
| Definition |
RecName: Full=Interleukin-13 receptor subunit alpha-2; Short=IL-13 receptor subunit alpha-2; Short=IL-13R subunit alpha-2; Short=IL-13R-alpha-2; Short=IL-13RA2; AltName: Full=Interleukin-13-binding protein; AltName: CD_antigen=CD213a2; Flags: Precursor |
| Primary Accession |
Q14627 |
| Accession Version |
Q14627.1 |
| Other SeqIDs |
sp|Q14627.1|I13R2_HUMAN,gi|2494720 |
| Organism |
Homo sapiens |
| Taxonomy |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo |
| Comment |
[FUNCTION] Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). {ECO:0000269|PubMed:20223216}.; [INTERACTION] Q14627; P36222: CHI3L1; NbExp=9; IntAct=EBI-4320063, EBI-6917454; Q14627; P35225: IL13; NbExp=9; IntAct=EBI-4320063, EBI-1647828; Q14627; P17931: LGALS3; NbExp=2; IntAct=EBI-4320063, EBI-1170392; Q14627; Q8IY26: PLPP6; NbExp=3; IntAct=EBI-4320063, EBI-11721828; Q14627; Q86XT9: TMEM219; NbExp=9; IntAct=EBI-4320063, EBI-20264080.; [SUBCELLULAR LOCATION] Membrane; Single-pass type I membrane protein.; [DOMAIN] The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.; [DOMAIN] The box 1 motif is required for JAK interaction and/or activation.; [SIMILARITY] Belongs to the type I cytokine receptor family. Type 5 subfamily. {ECO:0000305}.; [WEB RESOURCE] Name=SeattleSNPs; URL='http://pga.gs.washington.edu/data/il13ra2/'. |
| Source Db |
UniProtKB: locus I13R2_HUMAN, accession Q14627;; class: standard.; extra accessions:A8K7E2,O00667; created: Nov 1, 1997.; sequence updated: Nov 1, 1996.; annotation updated: Oct 12, 2022.; xrefs: X95302.1, CAA64617.1, U70981.1, AAB17170.1, Y08768.1, CAA70021.1, AK291957.1, BAF84646.1, AY656702.1, AAT49099.1, AL121878.11, BC020739.1, AAH20739.1, BC033705.2, AAH33705.1, NP_000631.1, 3LB6_C, 3LB6_D; xrefs (non-sequence databases): CCDS:CCDS14565.1, PDBsum:3LB6, AlphaFoldDB:Q14627, SMR:Q14627, BioGRID:109812, DIP:DIP-3340N, IntAct:Q14627, MINT:Q14627, STRING:9606.ENSP00000361004, ChEMBL:CHEMBL3713941, DrugBank:DB05078, GlyGen:Q14627, iPTMnet:Q14627, BioMuta:IL13RA2, DMDM:2494720, jPOST:Q14627, MassIVE:Q14627, MaxQB:Q14627, PaxDb:Q14627, PeptideAtlas:Q14627, PRIDE:Q14627, ProteomicsDB:60078, ABCD:Q14627, Antibodypedia:29593, DNASU:3598, Ensembl:ENST00000243213.2, Ensembl:ENSP00000243213.1, Ensembl:ENSG00000123496.8, Ensembl:ENST00000371936.5, Ensembl:ENSP00000361004.1, GeneID:3598, KEGG:hsa:3598, MANE-Select:ENST00000243213.2, UCSC:uc004epx.4, CTD:3598, DisGeNET:3598, GeneCards:IL13RA2, HGNC:5975, HPA:ENSG00000123496, MIM:300130, neXtProt:NX_Q14627, OpenTargets:ENSG00000123496, PharmGKB:PA29788, VEuPathDB:HostDB:ENSG00000123496, eggNOG:ENOG502RV4W, GeneTree:ENSGT00940000159971, HOGENOM:CLU_054773_1_0_1, InParanoid:Q14627, OMA:DCIYYNW, OrthoDB:1151666at2759, PhylomeDB:Q14627, TreeFam:TF331549, PathwayCommons:Q14627, Reactome:R-HSA-6785807, SignaLink:Q14627, BioGRID-ORCS:3598, ChiTaRS:IL13RA2, EvolutionaryTrace:Q14627, GeneWiki:IL13RA2, GenomeRNAi:3598, Pharos:Q14627, PRO:PR:Q14627, Proteomes:UP000005640, RNAct:Q14627, Bgee:ENSG00000123496, Genevisible:Q14627, GO:0009897, GO:0005576, GO:0005615, GO:0016021, GO:0043235, GO:0019955, GO:0004896, GO:0019221, GO:0016064, GO:0002638, GO:0043305, Gene3D:2.60.40.10, InterPro:IPR003961, InterPro:IPR036116, InterPro:IPR013783, InterPro:IPR003532, InterPro:IPR015321, Pfam:PF09240, SUPFAM:SSF49265, PROSITE:PS50853, PROSITE:PS01356 |
| Sequence |
mafvclaigclytflisttfgctsssdteikvnppqdfeivdpgylgylylqwqpplsldhfkectveyelkyrnigsetwktiitknlhykdgfdlnkgieakihtllpwqctngsevqsswaettywispqgipetkvqdmdcvyynwqyllcswkpgigvlldtnynlfywyegldhalqcvdyikadgqnigcrfpyleasdykdfyicvngssenkpirssyftfqlqnivkplppvyltftressceiklkwsiplgpiparcfdyeieireddttlvtatvenetytlkttnetrqlcfvvrskvniycsddgiwsewsdkqcwegedlskktllrfwlpfgfililvifvtglllrkpntypkmipeffcdt |
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