VAEAG: Vaccine Adverse Events Associate with Gene

Record Information
Record ID	37
Pubmed ID	29358173
SNP
Gene ID	7490
Protein ID	P19544
Vaccine Adverse Events	hematologic toxicities, fatigue, fever, gastrointestinal symptoms, elevation of hepatic enzymes, and hypoalbuminemia. leukocytopenia, neutropenia, hepatic-andbiliary tract infection, nausea, and increased AST
Vaccine	WT1 vaccine
Gene Name	WT1
Official Symbol	WT1 transcription factor [Homo sapiens (human)]
Aliases	AWT1, GUD, NPHS4, WAGR, WIT-2, WT-1, WT33
Other Designations	Wilms tumor protein; Wilms tumor 1
Chromosome	11
Location	11p13
Annotation	Chromosome 11 NC_000011.10 (32387775..32435539, complement)
MIM	607102
DNA Sequence	>NC_000011.10:32387775-32435539 Homo sapiens chromosome 11, GRCh38.p14 Primary Assembly TTTCCTTTTGAATAGACTTTAATTGAGAGCAAAGTGAAAAATGCAGGTTACAATTTTAAGTGTTATCATC AATATCTTGTAAGATCAACACCCAGTGATGCATCTAGTACTTATACAGTCCTAATTTTAGTTGTCAAAGA GCAAATCATTATCAGACATATATTTACACAGTAATTTCAAGCAACGGTAAATAATAAATTCCCTCCCTTA AAAAACAAAACACAACACAACACACACACACACACACACACACACACACACACGACCATCTTTAAACAAT GGATTTCCTCACCCAGTAAGTCTCATTTTTTTCACATATACTTGTAGACCCAAAGGTCCTTAAGTTACTT AAAAACAGTCTTATCAGTGGAGATCCTGGACCATCCCCTATTTTCTTTTAAAGTCACTTTCATTTTTACA ACTTGAAGCCATATACCAGCATGGTTTTTATACACTAAGGACACTCCCAGTGATGAAAATGAATTCCCCT CCATTTGTGCAAGGAGGTATGTACATCTATAAAGACACATATGATTACCACTCAAAAGAGTCAAAAACAT ACACAAAAAAATCTCAGATCTTCATAGTTTCTTAAGAGCAGTGTGCCAGTGTTCACATTGAATTAACTGA ATGGTAAAATTCTTTTAGATTTCTATACAGAGGTACTGGTTAGTTCTGATTTTTTCTTCAGCTGCTTGAA ATGCATGAGCTTTAAAAGTTGCCTGGCAGAACTACATCCTGCTTTCCAGGTTAGCAGCCTGGCTGACCTC GGGAATGTTAGACAAGATTCACCCCCGATGCCTTGCTCTCTGATTTATTTCTTGCTGTTGCTGTTAGTAA ATGGAAACCATGACAAAGTTTACATTAGCAGACACATACACATGCCCTGGCCTATAAATATTCCATGATA GAAAATGGTACAATAATTCCATCCCCAGCGAAAACGAGCATAAAAAAAGAAGGGAAGGGTCAGGGGGACA TGATCAGCTATGGCTCTTCTTACAGTAGAAAATCCACACCAAATGGCAATGGGCTTTTAACTAACCAGAC ATTGTTAGCTGCTTCTCCAGGGCCTGTGAGTCAACTAAAAGTAGGCAGGGCAGAGACCAACTCTTCCAGG CACACCTGGTAGTTTCCAGAAGCACCGGTATCTTGTCTTGGAAGTTGGATGAAGAAGATCAACTGAAGTT TCCTTTTTAGTGAGGAGGAGTGGAGAGTCAGACTTGAAAGCAGTTCACACACTGTGCTGCCTGGGACACT GAACGGTCCCCGAGGGAGACCCCTCAAAGCGCCAGCTGGAGTTTGGTCATGTTTCTCTGATGCATGTTGT GATGGCGGACTAATTCATCTGACCGGGCAAACTTTTTCTGACAACTTGGCCACCGACAGCTGAAGGGCTT TTCACCTGTTGACACAATTGCCAGTCAGAGACACTTGCAACAAAGAGACAGGCACAAGTTCAACTATCAA GGCCCGAGTGAAGTCATCACAAGGCACCCACTCTGAATTTCCCATCATTCTGTCCCTGAGCTAACCAACT GAGCTCATTTCCCAGGCAGCCTTGAAACAGCAGCACCTCTTGGGGCTTTAAGGATCGAAATATTGTAAAA AGTTATATTCTTAGGTCAGAAAACTTGGAAAGTGGGAGATAAAGAATGAGTCAAGTTGGGGGAAATGTCT GAGCAATTCATAATTAAGGGGAAAAACGTTTGTTTCAGTCTCTGCTGATAGAATGTTTTGTGAACTGTGT AAATTTCTCCCCCTTGTTGAGTAAGTTGGGAACTGAGATGAACTGGGCTGCAGAAGCCTCTGGGTCATCT ACCCTGGGTATTACTGAGTGATCACTGTCCAGGGATCTCAGCTGTGACTGAAGCTTTTAACACTTCTATC TGTGTAGATACCCTGGATGGGCTGGATACTTTAAAATAAATCACTGATACCAGTTTACATGTTATGTGTT GTTTTTTTTTTTCTCTTAAAGTGTTACTGAGAGCATAATCCTGTTATATGGAAGATTCTAGTTGGGGCGT GGTTCTTAGATTTTTAATAAGCTTGCCAAAAGATTGAGGCTTCTCCACCCAAAGAGCCCTCAGACATTCT TTCCAAGCCTCATTCTCATTAGGGAGAATAACTACCATTTATTTGATGCTTAACATATGCCAAGCCTTGT GCTGGGCTTCACACACGCACACACACAACCTCATGTACTCCTTACAACTGCCCGTAGGGGAAGCGTTATT ATCCCCACTCTACAGATGAGGTAGGACATCTATTGAGGGCAGATCCAGGCAGAACTCAAATCTCCAGGTC TGTCGAATTCCAGAGCCCGTGCTCTTCCCTGTATCACACCTCCCAGGCCTAGCCATGATGGAAAAGCAGC TGCAGCTCCATCTTAAGGAAGAATGCACAGAAGCTAAACCCTGTGCCACCTGACGGATCTTCTCAGATAC TGCTGGTCCCACTTGGCCTTCTCTGAGAACTACTGGTTTGGACAAGCACTGAGAAATGTCCCAGGAGGGC TGGTGTCCCAGGGTCAGACTGGAGGCCAATCAAATGTGGTATTAAACAGTCTGCTGGCAAAACAGGTCAT GTCACACTTACTTGGGGAGTGTGACAGCCGTGTCAAAGGGACTATAACACTTTGCCACCGAATTATGAGC TCAGGACTAAGTTAAAGAAGCATCAAAGGCACCTGAGGAAGGGAAGCAAGATCCCATCCTGCCAACCATG GGCCACAGGTGCCTTGGCTCTGTTTTTAAATGCAGCCAATTTGGGCGAAGAATCTGGGGCTGCTCAGGGG TTTGTGATGTCATGTTTTCCTTCACTCGCTGTTCCTCTGCTCTTCCTGGCCTGGCTCTCACTCTCCAACC CCACCTCCAGCAGTGCTGTTAAGGGCTGGCTCCTAATGGACTAATCCCAACCCTGTCTCTTGTCATCTTC ATTCCTCTCAGTCTCTCAGTGGTGTTCAGCTTTGCTGACTTTGATTCTCTACTTGACTCTCCATGCTCCC TGGACTGCAGAGTAAATATCTGCCCCTTCTCCAATAAAGAAGCAAGTGGGACAAGGTGGGCTGGAAGCAG ACAGAACTGGATTTGCTCCTTACTAGCTTTGTGACTTTAGATAAGCCATTGAATTATTATTGCCTCAGTC TCCTCATCTGTAAGATGGGAATAAAACATGCCTACCTCATTTTTTTTTGTTTGTTTTGTTTTGTTTTGTT TTGAGACAGGGTCTTGCTCTGTTGCTTGGGTTGGAGTACAGTGGTGGGATCACAGCTCACTGCAGCCTCA GCCTCCCAAGCAAGGTCTAGTGAGCGTCCTACCTCAGCCTCCCCCAAATAGCTGGGACTATAGGTCCACA CCACCATGCCCAGCTAGTTTTTGTATTTTTTGTAGAGACAGGGTTTTGCCATGTTGCCCAGGCTAGTCTT GAACTCCTGGGCTCAAGTGATCCACCCACCTCATCCCAAATAGCTGGGATTACAGGCATGAGCCACCACA GCCGGTCCTACCTTACTCTACTTACAAGCATGTTGTGAAGATAGACTTAGATAAGCTAAATATTAACGCT CTTTCCAAAGGTAGAAAATATGCAACAAAGGTGGTGCTATTTTTATTATGAATCACACCAGCCTTGCAGA AAGCAAAAACCTTCAGCAGCCAGTAAATGAATGCCCTATTCTCCTCTCTGTACTAGTATGAAGGAAATAA TATCCACACACTGATACTGGTCCAGCAGAAACCAAGACCGCTCCTGGTGCATTAACTTTTAACAGAGCAA GGACTCAGTTCTCTGAAAATAGTGCCATTAAACATGTGCTCTCAGAAGAATAAATATTTGGCTTGCTAGA ATTTCTGCTGCTTTTCTGTAAAGTTGATTATCGTATCAAAGAGAGTAACAAAATGTGTGATGCAACAAAC TGGAAACAGTAGGGACCTGGCTTATCTCTTCATTTTCATTCTGCACACTCCAGCCATTCTTTTCCCATCT TTCTCCTTCTCTGTATTTCCACCCTCCCCTTCTTTAAAAAATGTTATTATTTATTATTTAAAGATAGCCA CGCACTATTCCTTCTCTCAACTGAGTCTAAACCTTAGAACTTTTACACTAGTCTTTTCCAATCCCTCTCA TCACAATTTCATTCCACAATAGTTTAAAAAAATAATGAAAAATAAATGTGAAGAAAAGTTTACGCACTTG TTTTACCTGTATGAGTCCTGGTGTGGGTCTTCAGGTGGTCGGACCGGGAGAACTTTCGCTGACAAGTTTT ACACTGGAATGGTTTCACACCTAAATGGACAGAGAAGGTCTAGCCTCGGCCCTAACAATGTGGGCACAGT GAGGCCCACAAGGCTGACTTCCGGCAGCTGGAGGAGCCCAGCATTTCCTGCCATGCCTGCAATGTCTGCA TCTGCCTCACCCTTAGATTTCCCCAGTCCCCCAGGCCCAACAAGAATCACTGATTCTGCACAGTAATCTT CAAGGACCTGCTTCTGTCTTGGGAACAACCATTCCTTAACCACAGAGGTCCAGCTTCTCACCAGCTGGAA GATCTCAGCTGTGTCAGAGACAGGAAAAGTGAATCACACGCTACAAATTGGATTCCGCTCTCCATCACCC TCATTCTTTGCTGATGCTCAGTGTATCATCAGCCCACTGCTAGTGGGATCTCACTGTTCTGTGGTTTGCA GGGGAAATGTGGGGTGTTTCCTTTTCTTTCTTTTTCTTTATTTAAGAGGAGGAACATCTCCAGAGATTAT GGGGGGAAAATACTGGAAAAACTAAACACATGGCTGACTCTCTCATTCATATTCAACAACAAAGAGAATC ATGAAATCAACCCTAGCCCAAGGGAACACAGCTGCCAGCAATGAGAAGTGAACCTACAAACCTGTATGTC TCCTTTGGTGTCTTTTGAGCTGGTCTGAACGAGAAAACCTTCGTTCACAGTCCTTGAAGTCACACTGGTA TGGTTTCTCACCTTGGGGAAGACACATATTCTATTTGAAAATGATACTGGAAAAGGGGATCTCATTAAAG GCAACCTCTCCTACTAGGACTGAACAGATCCCAAAATGCCTAAGGCACTTCGCTGGAGCTTGTTAGGGTA GGATGATCCCCAACTTGCAAGTTACAAATGAATGGGAGCTCAGGGGCCAGAGGATTCTGCCCCAAGGCTC ACATCTAGCTCTGCCATTAAAAAAAAAAAAAAAGCCCTGGGTGAGGTGTGGTTTCTTTATTGTAAAATGG GTCCAATAATCCAACAACTTTAAAGGATTTATGACCTTCACATAAAGGGCTCAGCCCAGAGCCTGGCATA GAAGGCGTGCTCAAAAACTATTAGCAAATAAAAAACAAAATCTTTAACTCCCAGGCAGAATCTGAGGCAG AATTCTGGGATGCATGTGCCTTGAGGTCAACCTCATGAAATAAGAGTTTTATGTTTTAGGGCCCAAAGAT CTGGTGTTCTTTGCTACTGACTCCTTGTTCTTGCATCAAGCAAATATGACTCCATGGTTGTGAGACCCTC AAAACACACCAAAAGCACTGAGAAAGTTTTTGGTGTGCTTTATCCAAGAGAAGTCAGTAGTGGGATTACC CAACCTCCTGTCTCAGAATGGAGAAGCCTCACCCCTGTCCTCACTAGAGAAAGTTCAGCCAAATACTGGG ACCTGAGCCCCAAGAGAAGTGAGCAACCCCAGGCCTTCCCACCTTCTTAGGAGAATCCTGAGTCACAGGC ATCTGGGATGGAAACAAGCCATTCTAGAATCAGTCAGGTCTTTCTGTTGCAAAGGCAGCCCCCTGTTACC TTTCCAATCTCAAAGCCTGGGCTATTTCCCTCATGAATCTCTATTCCCCACTATGCCAGAGCTCACATCC TGAAGTCCTCCTTGCACTCTGCTCACACTAAATGTCCCCCATCCCTATCTCCACATCGAAAAGTCTCCTG GGTGTCTCCTTCTTCTGCAATGCCTGCTTGGAAACTGCATGGGCCAATTTCCCTTCCTTCCCTCATTACG ACATTTATTCCAGGCTGTCTAATGTGGTGAGCTGTGTCTGGGTCTACAATTCTACAATTCTTCAATGGGT TGGAAAATCCTAAGGGCTGGAGCCTTTTTATTTTTATTTTTTCTCAGAGACAGAGTCTCTCTCTGTTGCC CAGACTAAAGCGCAGTGGTGTGAGCCTAGCTCACTGCAGCCTCGAAACCGTGGGCACAAGCAATCCTCCT ACCTCAGCCTCCTGAGTAGCTGGGACTACAGGCATACACCAGCACACTTGGCTAAATTTTTAAAAATATT TTTTTTAGAGACAGGGTCTCACTATATTGCCCAGGCTGGTCTTGAACCCCTTAAGCAATCCTCCCGCCTA CGCCTCCCAACATACTGGGATTACAGGTGTGAGCCACTGCACCTGGCCCCTTTCTTTGTATTTGTATCCA GGTTGGTGCCTTATGTTTCACCTCTGTGAGCTGGAGAAGATGTTACCCCTATTGAGTCTGATTTCCTTCC CCTGCCTTTGAGCTTCTGCTCATCTATCACTTTCTCTGCCCAAACTACCAGCCTCCACTGGCTAACCCAA GCTGTTCTTCCTCTGAGAAACTTTCTCGGATGACCTTAGTTCAAACTGATACCCTCCAAACCCCTCGGTA CCTCCTGTCTCTGATTTAGTACATGATCATGTACTCTCTCAGTCACTTTTCATTTCTTTATATCCTAGCT CCCAAACAAACCAGGAACTCTTTGAGAAGGAGGATTATAACCTGCAGTTAAAAAGAAGGAGTTTGAGTCC TCTTTCTGCTATATCCTATACTCTTCATAAATGTTTTGTGAGTGAGGATTAAATGAAATATACATGTAGA GAGCCTGACACCCAAAAAGTACTTAATATAACAGTCTGTACTGTTGTTATAAATAAATAAGAAAATATTG CTCTCTTTCAAGGGGGACTGTAGGATTGTTAAATACCAACCTGCCCTCATCTTCTGCAAGGAAGAGTTTC TTAAAGGCTCCAGTGGGTCTGGGGTTTTGGCTGTCTTGTTCACTGCCTTCCCTTCACACAGTTGTCTAAC CCTCACTGCATTCTAAGTGCTTCTCTCTCACTAAAAGTTTCTACAACCATATTGCCTTCATTTATTCCCT TGCATTTTTCAGGCAGGACTTTACTTTCTCGTTTTCCTTATAACCTTGACAGTCACTTTTCAAATGATCC CATTTGGGGAAATGTGTAAAAACATAACATGCCACTGGTCCCCTCCTTTTTAGCCTCAAAGTCTGTGGCC CACTGAGTGCAAACTCAGATTGACACCAGAATTGCATCCTCTGGACACAGTGAATTAGCAAATTTCAATG GTCCAAGGAAATCTGAATGCAGCTCACTTTTTTCTCCAGCTTCCCAAGAGCAAAATCAGCAGTAATAACA CAGTTGCAACAGTGATCCTATAATAATGCTGTTCTTCGATTGTGGAAAAGGCAGCAGTAGCTCCTCTGTA GGAAAACCTGGGTTTTACCACACTCCCACACTCCCACCTAGTGCCCACAAGGCCCAGAGTAAACGTTCTG TGACATGGCTGTCCACATTCAAGGTGGCCAACACCAAACAATGCCAGTTCTCTGTTTCCCAGAAGCAGCC TCTCTGACCTGGGGGAAAATCCAGTTTCATTGGCGTATCTTCAAAGATAAAAAATCATCATCTCTCTCTC TCCTTTTTTTTTTTTTTGGCAGAGTCTTGCTCTGTCGCCCAGGCTGGAGTACAGTGGTAAGATCTCAGCT CACTGCAACCTCTGCCTCCTAGGTTCAAGCAATTCTCCTGCCCCAGCCTCCCAAGTACAGGTGCGTGCCA CCACACCCGGCTCATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTGGCCAGGCTGGTCTCCAA CTCCTGACCTTGGGTGATCCACCCACTTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCCCCATG ACTGACCTTTTTTTTTTAAGTGATCACTAAAAAATCAAACTAACAATCAATTTTCCCCTTCCTGTCTAGT TGATTATTACTGACCCAAGCAGGTAAGTTTTTCTTTGGACCATCTCTTCTAAAATTTCACAATGATCTTG CCCATCGACCTCCTAAAACCATCTGATGACTATATTCCCAGGCCAGCTCCTCTCTCCTTAGAAATGCTAA TAGTATTCTAACACCAACACGATTCCTACACAGGTCTCTTTAATTCTGTGGCACTTTCTCTCTACCACTC TGCTCTGCCTTTCTGGAAGACAGTTTACTGACCTCTGTAATAAAGGATAGATAATCAGAATGCAAAATGG CCCCACAGCCTCTTTACAACACCTGGATCAGACCTTTCAAAGCAGTGCTTACTTTCCATCCTGGAAATAA CCTGGGTCCTTAGCAGTGTGAGAGCCTGGAAAAGGAGCTCTTGAACCATGTTTGCCCAAGACTGGACAGC GGGCACACTTACCAGTGTGCTTCCTGCTGTGCATCTGTAAGTGGGACAGCTTAAAATATCTCTTATTGCA GCCTGGGTAAGCACACATGAAGGGGCGTTTCTCACTGGTCTCAGATGCCGACCGTACAAGAGTCGGGGCT ACTCCAGGCACACGTCGCACATCCTGCAGGCAGAGAGTAAGAGGAAGGGAGGCTTTAAGCCACATGTGAA CATTCACGTAGGTCTTGAGGGAGAGTGAGCACTGGAGTATATCCAAAGAAGGGGTGGCAGGTGCAGACCT AAAACCACTCCCATTCACACTCCAGATCCCCATGGCAGACATCAGTAATGGATGCTAGATCAGGACATTC TACAATGCAGTGCTCTAAGATCATCACTACTGAGCAACCAGAAGTGGCTGTTGAGATGAAACCTACATGA AATGGCTGTCCCAGAGCCTCTGCAAAAGAAATGCTGGTACCTGGAAGAGCTCCCAATCCATTCTATCTCT CAGCTTCTCCTCTTGAGGTAGTGATGTCTGCAAGTCCAAAGTCCCAAAGTCTAACTACTCCCTCCCACTT GGAGTCATGACCACATGACCTAGAGCCAGTCTGCAATGGGTGGGGACATCCTTATTAGAAAAAAGTGGGA TAATGAATGAGCCCCTAACTGACCAGATCGTCCAAGTATAAGTAAATAACAAGGAAGAAGAAGCCCCTGG ATTTGGGGATCCCATCTGTGAAAGGAAGCAAAACCCACCAGAAGGCCATGGTGAAGCCAGCACAACCTTT AATAGTGAGGCCAGAAAGCACTGGAATCCATCTGCCTTCTGTGCTCTGCACACGTCCTTTGCAGGGCATC TGTTGCTCCCCTTTATCTTGTGGAAGTGCAGTGTGTGTGTTGTCAGTCTTCCAAGAATAAGAACTGGAGG AAAACAAAGAGGCAAGCTCCCCTTCCTCTTCTTGGGGTCAGGGAGTCATAAATGGGAGCTGAGCAAGTGC CTGAGTGGCCACTAAATTCTCCTCATTCCTTTATAGATGAGTAAATCAACCCCAAAGGCGGTGAGATGCT GACACAAGAGTGCATCCATGTTTTGGTTTTGTTTGTTCTTAAGACAGGATCTTATTCTGTTGTCCAGGCT GGAGTGCAGTGGCACGATCGGGGCTCCTGCAGCCTCGACCTCACCAGCTTAAGTAATCCTCCCACTTCAG CCTCCTGAACAGCTGGGACAACAGGTGAGAGTCATCATGCCCAGCTAATTTTTTTTTTTTTTTTTGGTAG AGATAGGGTCTCCCTATGTTGCTCAGGCTGGTCTCAAACTCTTGAGCTGAAGGGATCCTTCCACCTTGGC CTCCTAGAGTGCTGGGATTACAGGTGTGAGCCACCATGCCTGGCCTAAAGTGCATCCATGTTTTGTGCTA AGACCTGGAACCACTTCTGAATATAACCAACTCCTTGCCCTGTGCATTTTCCACTCTACCCCATGCTTAT GTTCTAGTCCCTATTTCACATTGCCCTGCACTGAAAGGTCATTTTCTTTTTTGGAAGAATAAATGCTGCA GTGACATACAACACAACATTGATGTTAATAGGCCATAGTGTCTCAGGGATAATGAAGGCATAAAATTAAA TGGTGAGCCAGCTGTTGGATTGGAATACTCAATACCTGTCTGGTCTGGAGTGTTTTAGAGGCCATGGCAA GTGAGCCTGACAAACTGGGCTTGATGGGAAAGAAAGCAAAGGAAGCATTTTCCATTTCCCTTAATTCATC CTAGAAGCAGTGCACATGGGAACAGGAGTTGTTAATCTCAGTAAGGGTCCCGGTGAAGGATTCTGATTGT ATTCGTCAGGGGAGAGGCTTGATGTCTCCCTAAACCGTCGTCAGATTTCCGTATTTCTGTAACCCTTGCC TTTATTGCTCTCCATTGAAAGGCTTGGGAGTAGGGAGCACACTGTTCTTTCTTCGTGACACTTCTGGAAA CATTAATCAGAACATCTCAGAGCTACTTGCCCCACGTATCATGTGGGGTCTGGCCCAGATACAACTTATA TCTAGAGTACTGACCATTCTGGTGAAAGTATCACTGCTGTTACTCAGGTTGCAGCCATGGATTGATGTTT ATAAGCCATAAATGAAACCCTTAGTAACTGTATGTGCTTCTGACCACCCAAAACAGAGACTCTGCAGGGA AGGCAGACTGAAGGTCTACGGAGGTGGCAGACCAAAAGTGTCTATTGAATTCTCCAAAACTTTTACCTTT ATACTTTACTTTCTTCATGCTCCTTGGAGACTTCTCCCTCCCACAAACTGTTCACCATCCTCTGCCTCCC TAAGAAGCAGTATCGTGAAGTAGGTATAAACAGGGGGTCTGAAGTCAGGCAAGACCTGTGTTATTAGTCT CGGCTCCAATATTTACTAGCGATGTGATTCTGACATTATTCATCACCTCTGGGCTTCAGTTTCCCCATCC ATGAAATGGAGAGAATAACAGTACCCACCTCATAAGTGTGTATTGCAGATGAAATGAAGGGGGAAAGGCC ACAAATAGACAAGGAGAAACCTTACATGCATATTGCTAAGAGAAAGAAGTCAGCCTGAAAATGCTACATC TAGTATGATTCCAACTATATGACATTCTGAAAAAAGACCGAGCCGGGCACAGTGGCTCACGCCTGTAATC CCAGCACTTTGGGAGGCCGAGGCGAGTGGATCACCAGGTCAGGAGATCAAGACCATCCTGGCTAACACTG TGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGTGGGCACCTGTAGTCCCAGCT ACTCGGGAGGCTGAGGCAGGAGAATGGTGTGAACCCTGGAGGCGGAGCTTGCAGTGAGCCAAGATAGCGC CACTGTACTCCAGCCTGGGTGACAGAGCGAGACTCCCATCTCAAAAAAAAAAAAAAGAAAAAGAAAAAAA AAAGACCGGTGATTATTGGGAAGAGAAGAAGAGGGAGGGAAGAACAGGTGGAGTGTAGGGAATTTTAAGG GCAGTGAAACTATTCTGTATGATACTAGAATAATAGGTACATGGCATTATGCATTTTTCAAAACCCATAG AACTGTACAACACAAAAAGTGAACCCTAATGTAAACTATGGGCTTTAGTTAACAATAATTTATCAATATT GGCTCATCAATTATAACAAATGTACCACATCAATACAAAATGGTACTAATAGGGTAAAGTCCATTTTTCT AAAGTCCATGTATAAAGCTTAGCACAATGCCTAGTATATAGAAAATGTCCAGCCATAGGCGGTACAGTTA GTATGATGATCATCAACACTTGGCAAGATGTGAGTCTACCTGTGGACACTTTACGATGTAGACCAAATCT TAGAAGTCAAAGGTCCAAGCGGTTAATTCAAGCCCAATTAGCTTAAATACAAAAGCTGCACAGCCCGCCC TGGAGAAGTCAAATGGAGCAGTAAAGGCAGAAAGGAGAGGATTCTGTTAGGACGCATCTTGCGCAGCGTC AGGCAGCGGGGCAGCCTCTCTAGGAGAGGACACAGCCGCCTTATCAGACCCAGGGGACGAGCAGGTGTCC CTGATGTTAAAGGAGCCTGCAGTGAAGAAGAGGCTGCCAGGGCCAAAGAGTCCATCAGTAAGGAACTAAA GGGCCGGTAAGTAGGAAGAGGCAGTGCGGCCCCCTTCCCGCTGGGGCCTGTCTGTGTGCTCACCTGAATG CCTCTGAAGACACCGTGCGTGTGTATTCTGTATTGGGCTCCGCAGAGGATGGGCGTTGTGTGGTTATCGC TCTCGTACCCTGTGCTGTGGCTGCAAACACAAAGAAGGGAAAAAGGCTCAGTGTGGCTCACAGTCGCCAT TTGGAAATGCTTATCTGCAATCAGGAGGGAATGATGGTTTTTAAAGCTCACAGAACAAAAATAGTTGGTT TTTGCCTCCCTCCATGGGGCCACTTTAGATGCAGGGTTCTGCGGAGGGCGAGGCCCCTGGATCCTGGCCG CCACCTCGCAGCCCCTCCCTCATCCTCCGATTCTCGTAGGCGTGCACCGTCACGGTCTAGGTCTCGCTCA GACAAGCCGAGGAAGACCACAGTGGCAGGGTTTCATCCTCGGCAAGTTGTTTACCATCTAGACGGCAGGG CTGACAGCTGCAGGTATCTCAGGAATGAGCAGAATGCCTCAAGCTTCACGTTAAGTGCACTGAATTTGTC GGCACCTCATGACTCAGTTTTTACCAGATAGCACCAAAAAAGTGATGACGCAAGAAGAGATGTCATGTCC TCAGAAGTGGGGATTACATATCTGTGGCCTCACTCTGCTTAAATGACAGGTCAGTTTTCCAGATCAGCTT AACTCTTGGTAGCCAGCCTGTGCTGTAGGTGGGCACTGAAGAATCTTCCTCCAGCATTCCACTGACTAGT CCCCTAACTGGTGCTCAGGTTAAGCTTCGACTACATAGGAAGAGCTGAAAGATGTGCAATGCTGAAAAGG ACAACTTGAAAGGAACGAATGTTCTGTTCTAAAATTATTCTCTCCTTCAGATACAATGCCTCTATCTGCT CTACAGTTATTTTACTTCCAGATGAGATGAGGCAGACTGAGGTTTTTCACCCACACCAGCAGCACATTAG AATTACACCTAGAAGCACCGAGGAGAGCTCTTATGAAATAGCTCTGTGAAATGATGCAGCTGCTTTGCAA AATATCTGGCAGTTCCTCAAAAGGTTAGACATAAAGTTAACATATGACCCAGAAATCCCACTCTTAGGGA TATTCCCAAGGGAAATGAAAACAGACGTCCACACAAAAACTTGTATACATTGTGCATTAGCAGCATATTC CTAAGAGCCAAAAAGTAGAATCAACCCAAATGTCCATCAACTGATGAATAGATAAATCAAAGAGAGTATC TTCATACAATGGAATATTATTCAGCAATGAAAAGGAATAAAGTACCAATACATGCTACAATATGGATGAA CCTTTAAAATACCGTGCTAAGAAGCCATTCACAGAAGACCACATGTAGTATGATTGCATTTCTATAAAAT GTCCAGAATAAGCAAATCTGTAGGGACAGAAACTAGATTAGTGGTTGGGTGCCTTGAACTGGGGGAGTTG GGAAGGCAAAGAAAATGACTGCTGAAAACGTCCTAAAATTGTGGTAATGGTCATACAACTGTGAATATAC TAAAAACCATTGCATTGTACACTCTAAATCGGTGAATCATACGGTCCGTGCAATCTATAAATCTGCTTTT AAAAAATTATCGGGGGGGGGTGTGGTCCGAGAAGGATGCATCAGTATATTTATTTATTTATTTTGAGATG GAGTCTCGCTTTATCACCCAGGCTGGAGTGCAGTGGTGCGATCTTGGCTCACTGCAACCACCGCCCCTGG GTTCAAATGATTCTCCTGCCTCAGCCTCCGGAGTAGCTGGGATTACAGGCGCACGTCACCATACCCGGCT CATTTTTGTACTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCCAGTCTCGAACTCCTGGCCTTA AATGATCCACCCATCTCTGCCTCCCAAAGTGCGGGGATTACAGGTGTGAGCTACCAGGCCCAGCCGCATC AGCATTTTTAAAAGCCTCCAGGTGGGATTAAACTGGCTGTCAGCACTGAGAATTCCATTCTCTGCCTCCA TTACTCTAACAGTTGGTTCCAGGGGTCCTGGGCAGGGAGGCAGGTAAGCTGGTGGGTGGATCAGCCCACT CCATCTGGTGTGGTGTGGGGAAGCCTGGAGTTGACCCAATACTCACTCACCCAGAGGAGAGAGTGCCTGA AGGAAAGAGTGTCTGCCAGGACAACTGAAATGTCCACACCCCCTAGGGCCACAGAAGCTGTAGGGTTTCA CATTTACTTCTGGCTCTAAGCATTTTAGAAAGAACTGCCTGCCCCTCTAACCTACCATATCTTGTCTCCA CATCCTTCAAGTAATTTTTGACTTATCTAGGGCAGGGGGAATGTCTCAAAGAAGTAGCCCCAGGGTCAAA CCTGCAAAAATTGGGCAAAAATGCCAAACCCAAAGAACATATGCCCTTCTGACCCTTAGAATGTGTTTGT CAGGAGAAAGAGGCTGTGTCTGCCTTCCTTTCAATTACTTGGTACAGACAGTGGGAAAGTGAGAGGTGAT GACAATGGCCATTTGGCAGCAGAAAGAGGGCAGTACCAGAATGGTGCCATGGTGCTGCCAGAACATTTTG CCTCAAAGGCTGTGAAGAGAAGCTGCCTTTGCTTGCTTCAGTCATCTGCATGGAGCCACAATGTGACTTA CACATTTTCTTTCTTTTTCTTTTTTAGAGCTTGCTCTATTGCCCAGGCTGGAATGTAGTGGTGCGATCAT AGCTCACTGCAGCCTTGAATTCCCTGGCTCAATTGTTCCTCCTGCTTCCATCTCCCAAAGAGCTAGGACT ATAGGTGCCCCGCACCATGCCCAGCTGATTTTTATTTTTATCTTTGTAGAAACAGGGTCTTGCTAAGTCC TCCATAGGATGGTCTCAAACTCCTGGGCTCAAGTGATTCTCCCACCTTGGCCTCCCAAAGTGCCAGGATC ACAGGAGTGAGCCACTGCCCCTGGCCTACTTTCCACATTTTCTAGGGCTGAAGGATTTCTAGGGACACAA CATTAAAGTTCTGCCATCGAAGGGTAAAAATTAGAAATCTGTCTTGACAGCTAAGCTCTGGGTGTTAGCT GGGTTCCTGGAGGGTGGGGGCATGGGAACAGACTTTCCTGAAGACAACTGTCTCATGAAATTAAGTGGTG TGACACTCAAAGGGAACAGCAATTTGCACAGCTGGATGCAAACCACAAACAAAAGAAGCAACAAGCAACA AGACTGTACCTGCCAAATATGCCAGTGGATTCTCCTACAAGGTCCATGAGGAAAAAAAAAACAGCCAGGC CCCCGCCTATGGGGACTTGGGTCTCCAAAGGACAAACACACCAATGCAATTCCACACTGTGGAAACCTGC AATTCAACACTTCCCAATGTAGTGTGCCCAGAACACCAAGTACAACGTACTGGCATCTGATGTGGTAGCA ATTCTCTCTAAATAAGTTTTTAAAAAGCAACTCGGTCTGGGAACCATAGACTAATAGAGATAGAAAGGAT CCAGAAAGGCCATCTACACCAACCCCCATTTGGAGCAGAAATCTCTTCCAGCTTATGCCCAACAGTTGAT CAACATGACTGGTGACTAGTTTTCAAGATAGCCCATTCCATTTTAGGAGAGCTTTAAAAACAAGCTGAAA TCTGTCTTCTCATTTCGGACTCCTGGAGAACCACTGAATGAATATTACTTTTTTTTTTTTTTTTTTTTGA GACAGAGTCTGGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCATGAAGTCAGCTCACTGCAACCCCCGCCT CCTGGGTTCACGCCATTCTCCTGCCTCAGTCTTCTGAGTAGCTGGGAATGCAGGCACCCGCCACCACGCC CGGCTAATTTTTTTGTAGTTTTAGTAGAGACGGGGTTTCAACGTGTTGCAGGATGGTCTTAATCTCCTGA CCTCATGATCCTCCCGCCTCGGCTCCCATTGTGCTGGGATTACAGGTGTGAGCTACTGCACCGCGCCCAG CCGCAAATATTACTATTTTACAGCCATCTGTGTGTATCTCCTCTGCCCCATTGTAAACTTGGCCTTGAAT ACAAAGACTCTCTGCTCTTCTCTGCATCCTCTAAACTCAGTGACTGAGGCCGGACATGGTGGCTCACGCC TGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACGAGGTTAGGAGATCGAGACCAGCCTAGCC ACCATTGTGAAACCCATCTCTACAAAAATACAAAAATTAGTTGGGCATGGTGGCACGTGCCTCTAATCCT ATCTGCTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAGTTGCAGTGAGCCGAGATCG TGCCATTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAGATTT CAAACAGTTTTCATGTTTTTCTGTTTTGTTTCCTAGTAGACTTCCTTTTGAGACATAAGATAATTGACCC TGCTGAATGACAGGGAGAAGGGATTTATGAGTCCTTGGCCAAGATAGTCAGGAAGATCACAGGAATTGAC AGCAAGGTGTCATGAGGCTATGGTTCCAAGTGGGGAAAAGAACGGTGAGTCTGGGGCAGGCAGGTAAAGT CACGGGAGAGGAGGTTCAGGGTAATATGACTGCTTCTCCTGTCCTGCCACAGAGACCACTCTGTGCTAGA AGCCACTCTCCAACTTGACAAAGATACTTTAGACAACAGTTCCTTTGGTTTTATTGTTCAACCAAGCACA AATCATCCATTTAAGCATTTAGTCCATCATCCCCTACCTTGTCCACAAGGACATCAAAAATATCAAATAT CTTTTGCAATGAAGAGCCACAATATTAGTGAACTTCCACTATTGGACTGGTAATTCTACCCAAAAAGAAA CGGACTTGGGCACGTGTCTTGCATACCACTAACCAACCTTGGTCATGATCCCTGTTTTCTCCCCAGCTTG TTCTCAAAGATCTGGCCTAATAACTTTTCCAAGAATTCATGCTAACTCTGTGGTTTCCAGAATCCACTGG GTTTTTTTCCTACTTGAAAACTAAGACATTTATCTGTCTCAACTCTTCGGTCACCTCTCTTATTCTCCAT GAATTTCCCGGTTATTGGATAAGGAGGCAGTTATTTCATGTGTTTGCTAAATTGGTCAGAATATGGATTG ACTCTTTTTAATTTAAAACAGAGCCATGAACTCAAATATTCCTATAGGGGCCAAGTAAGACAAGTAAAAT GAAGGCGACCCTAAAGAATGAGACGATATTGAACTCACAGGGACGGCTACCCTGGCCACATCACCCTCTG ACCAACAGAGGCAGCCACGACTCAGCTCTCCCAGCCAATAACTGTAAACAATGTGAACCCAGCATTGCTA TACTTTTCCATTCTCAAAGAAAAGTAGGAAATCTGGACTTTTTTGAGAGCACCTGAGTTATAAGTTCTTG CGAATAATTGAAATTTTAAAGAATCACTGTCGGGTCAAATAAAACACACACTCTAGATGGCACCACTGCA CTCTAGCCTGGGTGACAAGAGTAAGACTCTGTCTGTAAAAAATATATATATTTTTAATATACATATATGT TATATATAATATATTCATAAATGTATAATAAAATATATGTTGAATATATAAATATATACAGAATATATAC TTATACATAAATATATATATTTTTCAATCCTTAGAACCCTAGGAGTCATTCATTAAGTTCCATCACCTTA CACAAATGACAACTTCCTCCCTGGCCTCAGCTTCATGTAAAATGAAAATTACAGCACTTCCCGCATCAGA CTGATGCAATAGGTCAGGTAAGTAAATCACAGTGCTTGGTATGCACTCAATAAGTGTTAAACTGTTGCTT ATGTAGTATTATCCCCATTTTACAGCAAAGAATACTGAGGTTTAAGGAGACATTGCGTTATTTGCCCACA GTCAGATGGCAAGTGGCAGAGCTAGAGTTTGAGTCCAGGTCAGTGCTTTTCTTCCTTCCAAATGAGCTGG ATAATCCTGGTGGTATTAACCCCACCCTACAGGTTCACTTTTATCATCATGAGACTTGAACGACTCCCAG CTCTTTTCTCCAGCGGGATGAATGAAATTAGGCATGCTGAAGGTTTTAAAGGTGAACTGGGGTAGAGGGA AAGGACTAGGGTAGAGGAGAGTTGGGGGAGTGGGGAAGGACAGGTTTGAAACATTCCCACTTTAGCCTTC TTCAGCTTCTACTTGGAGGCACAACATGTAGTTTTGCATAAAGCAGTGGTCCCCCATGTTTTTGGCACCA GGGACCAGTTTTCTGGAAGGTCATTTTTCCACAGACCAGGGGTGGGGTGGAGGTGGGGGTGGTTTTGGGA TGAAATTGTTCCACCTCAGATCGTCAGGCATTAGTTAGATTCTTATAAGGAGAGTGCAACCTAGATCCCT CACATGTGTAGTTCACAATAGGGTTCATGCTGCCATGAGAATCTAATGTCGCCACTGATCTGACAGAAGG TGGAGCTCAGGCAGTAATTCGAGGGATGGTGTGGCTATAAATACAGATCAAGCTTTGCTACCTCGCCTGC CGCTCACCTCCTGCTGCAAGGACCAATTCCTAACTGGCCACAGACCACTACCGGTCCATGGCCCGGGGGT TGGGGGCCTTTGGTATAAAGAAAGCACAAGGCTAACTGATGGAAATGGCTGCTTATGTGCAACAGAGCAT GAAGTTTACCCTCCACCAAAAAAAAAATATATATATTTATTTCTATTGAACTGGGAAAATAAGCAGAAGC AGTTATCAGCAGAGCATGCACTTTGGCGCTTCACTTCTGGCAGTGGCCTGGACTGTACATTTTGCTAAAC AGCTTTAAGATGCATAAAAATGTATCCTGAGAAAATTTGCTTTTCCTAGACAGCTTTAAAATGCATAAAC ACGGCCGGGTGCAGTGGCTCATGCTGGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACCTGA GGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACCAAAAATACAAAAATTAGC CGGGTGGGGTGGTGGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGTCGAGAGAATCGCTTGAATCCG GGAGGCAGAGTTTGCAGTGAGCCAAGATCGTACCACTGCACTCCAGCCTCAGCGACAGAGCGAGACTCTG TCTCAAAAACAAAAACAAAAACAAACAAAAAATGCATACACACTTTCCTTAGAAAGTTTGCAAAAAGAGA AAAATGTCCCTCATATAACACAAATTGTGAGCCCTCTTCCCGCTAAAAACACGTACATTGAGATTTGGCT CAGGAAAAACAAAAAAACAAAAAAACAAAAAACAAAACACTTAACATTGCAAGAGTGGCTTCTTTAGAAA TGATTAACTTTGATATTCCACAGGCACATGAAGATTAATAAAAAGGAATTGAGGTTTTACAGATGAGGAA AACCAGAGCCGCCCTGGAATCCCTTATCAACAGAAGAAGTAAAAGAGAGAAAAGAAAAAGAGCCTTTGGA AGGCAATTAGCATTCATATGAATATTCAAAAAGGGGGAATTTCGGCCTGTCATTTCTCTCTCCCACCTCT AGTTATTGGCCAGGCAGGCATCCCCCCATCTTCACCTCCGTCTTCTCCCCTCTGCAGAGTTAATCAGATT GAAGGGAAGCACCTGGGGACATTCAAACTCTTGTGTCTCTAAAACATGGAATTTACCCATCAACCCCTCT TCTCTCCCCACCCTCGATACTCAGGGCTCATACGTGAGATGCTGAAATGCCTGATTCTTTTCAGTGTTGA CAATAAACCCCGCTGCAAGCCTTGAGAACCATCACCCCCTTGTTTAAGGATCTATGCTAAGAAACTATGC TTCCTTAAAGTTTAAACACAAGAGAAGAGGCTGAACACAGTGCCACTCATCAATTACATTTACCTAAAAA AGAAAGAAAGAAAAAGGAAAAAAGAAAATAAAAAAAGAAACCCAAATCGAATCAAGCCTCTAGGAAATAC AGGGGAGGCCAGGCGCGGTGGATCATGCCTGTAATCCCAGCACTACGGGAGGCTGAGGCAGGCGGATCAT TTGAGGTCAGGAGCTTGAGGCCAGCCTGGCTAACATGGTGAAAACTCATCTCTACTAAAAATACAAAAAT TAGCTGGGCATGGTGGCATTTGCCTGTAATCCCAGCTACTCGGGAGGCTAAGGCAGGGGAATCGCTTGAA CCAGGGAGTCGGAAGTTGCAGTGAGCCGAGATCGCATCAGCCTGGCTACAGAGTGAAACTCCATCTCAGA AAAAAAAAAAAAAAAATGCTGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCA GGCAGATCCCTTGAGGTCAGGAGATCAGGACCATCCTGGCTAACATGGTGAAACCCCGTCTCTACTAAAA AATACAAAACATTAGCCGGGTGTCGTGGCGGGCACCTGTAGTCCCAGCTACTTGGGAGGCTGAAGCAGGA GAATCACTTGAACCCAGGAGGTGGAGGTTGCGGTGAGCCAAGATTGGGCCATTTCACTCCAGCCTGGGCA ACAGAAGGAGACTACGTCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGAAAGAAAGAAAAAAGAAAAG AAGGAAGGCAGAGGAAGGGAGGGAAAGAATGAGAGAGAGAGAGGAAGAAAGAGAAAGAACAGAAAAAAAG AAACACAGGGGAGAGAGGACCAAGTTTAAAAGACTGTAAGATAAAACAATCTGCCAAATCCAGACTGTGG GATATTCTACCAGAAAACTGACCTGCTATTTCCAATAAACCAATAGTCTGAGAAGAAAAGGGAGGAGGGG GCTGTTATAATATAAGCTAGACTTAGGAGAGGACAACTACCAAATAAAACAAAATACAACAAAACAATAA ACCTCCGTGTAAATACTGTACTCTGTACTTACTGTGTACTCGTATGAACCACAGATTGCTGGACTTGAAT TAATCAGCCCTAAGAGACTTAGGGTCAAAAGATCCAGGAGTATTCCCTAGGAATTCTCAGTGGTTATGCC ACAGTGCTTAGGTTTAACACTTTACTCAATGAATATCCAATTTCCCTGTAGCCACAGTAAAGTAATTTCA GAAGTCACTTTCATATGCACTTATCAGATCTTATTTGGGGAATGAATAGATACTGGATTATCCACATTCA GAGCTGCTGGCAACCTGGCACAGATGCCCCTAGATCAACATAAATATTATTTTATTATTTGCTTGAGTGT GACATGCTCCATCTCTTTATTTTAAAAAGTAAAATTTAAAAAATACCAGAAATAATTAAATATTTTAAAA TGCTTGGGATGGGAAAAGTCTAAGCATGATCGAAAAGTCAAAAACTTGAAACTGTAAGACAAAAACTTAC TATTTTTACCATAAAATAAAAATATCTGACAGAAAAAAACCATTAACAGAATTAAAATACAAACCAGAGA AAATATTTTCATTACATATGACAAGCAAAATAACTCTTATAAAGAAAGCACTTTTTCTTTATTATTATTA TTTTTAGAGAGATGGTCTCTGTTGCCCAGGCTGGAGTGCAGTGGCATCATCATAGCTCACTGCAGCCTCA AACTCCTGGGCCCAAGCACTCCTCCCACCTCAGCCTCCCAAGTAGCTGGGACTATAGGCATGCCAATATG CCCAGCTAATTTTTTAATTTTTTTGTTTTCTATAGAGATGAGATCTTGCTATATTGACCAGGCTGGTCTT GAATTCCTGCCTCAGCTTTCCAAAGTGCTGAGATTACAAGCATGAGCCACCGAGCCTGGCAGAAAGAACT CTTATAAATTAATATTGTTACTAGATGATCTATCCCAGCTTCTGGCTAAAGCCAGCCCCACCAACTTATC TATGGAGCCCCTTCTCTCCCACCTCCTTCAAGGACACTGTTCCAGTGATTCTGTCCCCTCCCATTGACCA TTTTTTTCCTCCTCTTTTTTTCCTTTTCTTTTTTTATTTTTGTATTTTTTGAGACAGAGTCTTGTTCTGT TGCCCACACTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCAATTA ATTCTCTTGCCTCAGCCTCCCGAGCAGCTGGGATTACAGGTGTGTGCAACTATGCTCAGCTAATTTTTGT ATTTCTGTAGAGAACAGGGTTTCGCCACGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCA CCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCTGCCCCATTTTTTCCTCCT CTTGATCATTCTCATCAGCAAACAAACATACAGATACTTCTATCTAAAGATAAATAACTAAATAAAAGCA GAACAATTTAAAACAAAACCACTCCTTCTCCCGACCTTCTTTCCCCAGCCAGCTAGAACCCCATTTTTTT GCTCCCTTTTGCAGCAGAACTCCATGAAAGCATGATCTTTACCTCCTCTCCTTGTCTCTTAAATCCATCT GTTTCAGGCTTTTGTCTCTTCCGTCTAATATATTTAGAGGTAACTGCAATTAATAGTCTGATAAATGTTT CCAGAATTTTTTCTCTGAAGATATAAATACACCTCAAAATGTTTTTTTAAACAGTTATCTCTGGGTGGTG AGACAACAGATTAATTTTCTTTTCCTCTTTATAATGTTTTGGTCCCGTCTGAATTTTTTAAAAAATGATA AGCCTGTGTGACTTTTATAATCAAGGAGAAAATAACTGTTTTCATTTTAGATAAAGTCGCCATCTAGGCA TACAGAACTACATCTGTTGTTTTAAAAATGAAGAGTTAGAAATAAAGCTAGAATAAATAAACTTGTTCGC TTTTAATAGAAAAACTCCTACTAAAATATGCAGTAGCTCCTTGTTTCAGAGAAACACTTTTCTGGATAAC TTTTTATTAGTGTAGCTTCCAGATCAATGTTCTTCTACCTAGAGGTTATGATCTTTTCTTGGGCAGATGA CAGGCAGAAGGATAAATGGTGAGTAGAGGGTCTCAGAAGAGATCAGGGATAGGAGAAGTCCAAATACTGC TTTGGATCATTAAGGTATCTTCCACTCATCTGATGTAACCTCTCCCTCTCCAATACACACACACACACAC ACACACACACTTTTATCAATCCTCATTAACCTCACTTCACCTCCCTGTGCTACAATCACTGTTTCTCATT TCCAACTTGGCCCCTTCTCCATCCCAACCTTTCTTTCCTATCTTTCCTATTCAGCTCCTTTCTTCTCCAG ATCTAAACAAACCTAGCATTTTTCCTCACCTCCACAAGATGAAAATAATTCCTTGCTTTAAAATAAAATA GTTAGAATCATGGTATGGAGGTAAGTCTGCAGAGCCCATAAATATTTTTTAAGAGGCTGAGAATATTTTC AAGAAGTCAAAGCTATCATGACAACTTCGTGATGGCCTATAAATATGCATTTGCTGAATTGAATCTCACC TGAAGCCAATCATTTTTGTAAGAAAGAAAATGACACAAATGTACATGCATGGACAGGAAAGGGTCTAAAA TTTTGTGCAACATCATTATCATCATAGTTTCATCTAGGCTTTTGGGGGGAGTTTTAATTTCCTTCTCTGC GTAGTTGTATTTTCTAACTGTTCTATAATTTATACACATTACTTACATAATAAAAAAATTCAATACATTC ATCAAATGCATGTCCAAAAATAAAAGGATAGAAAAGGCCAACAGCCAGGGAGGAGAAAGAAGAAGCAGAA AAGTGAGAAGCAAAGGAAAGAAGCTTCCGAATCAGTCCACACTAAGTGAGAGGGACACAGAGCTAAGTCA CGAGTCTCCATCTTTATCAAACCCTGGAGTCCCATTCTTCGTTCTGGTTGGCAGGGTTAACAGACCTCAG GCCAAGTCCAATGCAAGGCAATAATAAAGAAAAAAAACTCTTTAAATGGCATTAAATGAAACTTTAAACG GTGGAAAATTAATAACTTGTTGCTGGGGGTGGAGATGGAGTAGGCTCGGCAATGCTGATATTCACAGAAC TGAGGCTCCCCACCTTCACTTTGCATCTCAGGCTCCGGGAGCCACTTAAAAGCAAGCTATCTATTTCCAA GAAGTAAATCTCTTGGACGGATACCTTATGTTCACGAGCCCGCGAGGGAAGGTGCTGGGCTGTGTATTGG AGCTCCCAGCCAGAGAAGACAGCTATCTCTTTTGGCACAGGTTCTCAGGGATGAGACCATGTCTAGCGGG GATTTTCTCCAGATTCGACAGCCTTGGCCCTACCAAAACGCACAGCTTTGTTTTCACCACACATCACTCA TTGTTGAGTCTTTTTTGTTTTTCCTCTCAAGCATCCACAGGTTGAATACTGTGTGTTCCCAACAGCCTGT GAACTTCTTGGACCAGCAAAGGGACATTCATTTTGCTGAGCACTCCTTTCACATTTCTATTGTGTTCGAT TTCCCACTCCCCCTACCCGAGTCCCCAGAGAATAACTTCTTCCTTGTTTTAATAACTTGGATCACAGTCA AGGTTGATGTGTTTCTCCATTTTGCAGGATATTTTCTTCAGAAGAGACAAAACAGAGGCCAACAGGGTAG GAGAGGCTTGTTCGGAAATCAGCAGCCATTGAGAACACACAGAAAATGTTTTCAAAGAAATAGAAAGCAG ATAACACAAGGCACCATCAATAGAAGGCTTCAAAATGGTGGACTCATACTCAGAAAGATTCCCCAGCAAC GTTTTCTCCCAGGGACCCACTTTAAAAATCTAATTTCATTTGTTTGGGGGTGAGGGAGAAGAAAGTACTT TCCGTAAAGTACCTTCTCACTGACTTAAATTGAAATACATTCTCCCATTGGAGGTCATAAAAGTAGCTGT GATCCCAGTGGGTATGCAGAAATTAGAAAATGAGTAAAGGGAGAAGGAGGAGAAAGGAGCGGTTCAGTCA CACAAGTATATCCCACCTCTAACACAGCAAGTTTTCATTTCATCTGCCCATGTTCTTTATAAAATCCTAT CCCCACCCATTGTAACACTGCTCCCTGACATCTAATGAAAGATGTCTCCGTGGACTTGCTTGGGATACAA GGAAACAAACCTATTCTTTGTGAAGCCACTTTTTTGAAACGAAACATTTTCAAGGAAAGAAGACCCGAAC CAGCATTTAGTGGGGTTTAGTCTGAGGTGCATGATCTTTTAATAAAAAATTGATAATGCCTCTTTTTTAT GAGTGATATGGAAATTACATCTTTCTTCTCTAAAACATGAACCAAATCACCAGTTTTTCCTGTAATAGAT CAACCTTGTCACATGATTTTTCTTAACATTGATTTCAAACAGTGTCAAGACACTAGTTATGAATGAACAC AAAAAGTTATGTGTCTGAATTTGTCTTCATGGAATACCTTTTCTCAAATGTATTCTCCATATTAATACTT TTCATACCATGGCAAAAGAAAGTAAATCCAGTATCACAAAGAACAATGACCCCAACCCAGATTGGTCTCC CCTGGGGAAAGGCCAAACTTTCTACTGGAATTACAGATTCAACTAAATCCAGTTCTGGGCTGTTCATGAG TTTGGAGGAGACAGCCAAGGTGTCACCATGTTTGAATGCTAAAAGTGAGGCAAACTGTGGGTCATGACAC ATCAGTGGGTTGTAAAATCAATCTAGTACATCACAATCAGCATTTTAAAAAATGAAATAGGATAGAGAGA AAAAGTCAGCATGCAGAGCATGTCATAAGAGTATTGCTCAGTGAAAATCTATGTTGTGTGTGTGTATGTG TGTGCACATGTGTGTATATGGGATCTCACTGTAAAGGGTATTTCTAACTGTGGTCACAGTCTAAAAGGTT TCCACCCATTTAAGAAGCTCTAATCTAGGGCCCAGGTCCTGGAGTCAGACAGAACTGATTCCAACATGGC TCTGCCACTCACTTACTATGTGACCTTGGTTAGATAGCTTAATCTCTCCACCTCCTCAGCTAAAAAATTG GATGTGGCCATAGTGTCCTGGGGGTGTTGTAAGATCAGATCAGAAGAGGAAACATGTACAGCCCCTCACA CGGCACCCAATACTGTTTATATACATCCTTAGATAAATGTCCAGTTCACAAAATGGAAGCGGAAATTCGT GGATTTACAGTATGTTCTACAGTGTGAGAGAAGATGGTAGGCAATTAGCTAATTGTAATTTTTGCTCTGC AAAACAGTTGTTCTTTTGTGGAACTATCTGTTGGGCCATCTAGCCCTTTTTATAACAGCTCCCTGAATAA AGTTAATATTCGAGAAATATACATATATATTGTGTTTGTTTGTTTTGTTTTGTTTTGTGGAAGGGTCTCA CTCTATCGCCCAGGCTGGAATGCAGTGGCCTGATCTTGGCTCACTGCAACCTCCGCCTCCCAAGCTCAAG CAATCCGCCCACCTCAGCATTCCAAGTAGCTGGGGTTACAGGCATGTGCCACCACGTCTGGCTAATTTTT TTGTATTTTTTGTAGAGAAAGGTTTTCACCACATTGTCCAAGCTGATCTCAAACTCCTGAGCTCAAGTGA TCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTATAGGCGTGAGCCACCATGCCAGGCCAAGAAATACA TTTTTAGTCAGGGCGCAGCAGCTCATACCTGTAATCTCAGCACTTTGGGAGGCCAAGTGTGGCGGATCGC CTGAGGTCAGGTGTTCAAGACCAGCCTGGCCAACATGGCGAAAACCTGTCTCTACCAAAAATACAAAAAT TAACCAGGTATGGTGGCAGATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAA CCCAGGAGGCAGAGGTTCCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGTGACAGAGTGGGAC TCCATATCAAAAAAAAAAAAAAAAAGAAATACATTTTTATTTCAGAAATCCTTTCTAAGATGTAAGTAAC GGACCAATGAAAACTCTTCTCATTTTTTTCTTATGTAGGATTGAACAGAACAAATTGTTCACACTTTGTG CTTCATCCTTATAATACAGCTTCTGCCTCCTCAGCAAGTGACTAACAGTACATGTCTAAAGACCTTAAAA AGTATCGAAATTATCTTAACCATGGAAATATCCAGCTGCAAATACATGCCAAATTCCTTATCTGTAATTT TTGTAACTGAACAAACAAGCCCCTGTATTACAGCATGAAGAAGTTTTTGAAACTGAAATGTACTGCTCAC TTCACAATCATGTTCTGTCTATCCTTGCTATTTAGCTTGGGGAAGGTTATCAAGTTCTGAGGAGAGGAGA AAGGAGAAAAGGAAGGGAGCCAGAAAGAAAGGGTGGGACCAAGAAGCCAAGGAACTTAAGACGAGTTAAG AACAGGTAGAAAGGCCAGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTCGGGAGATCAAGGTGGGCG GATCACCTGAGGTCGGGAGTTTGACACCAGACTGACCAACATGGAGAAACCCCATCTCTACTAAAAATAC AAAATTAGCCGGGCGTGGTGGCACATGCCTGTAATCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATCGC TTGAACCCGGGAGGTGGAGGTTGCGGTGAGCGAGATGGCACCATTGCACTCCAGCCTGGGCGACAAGAGC TAAACTCCGTCTCAAAAAGAAAAGAGAATGGGTAGAAAGACAGAATGCTAAAACTGTCAGCAGTCCCCCA GATGGAAGACAGGAGAGAAATAATTTAAAACAACAGAAAGCCTTTTCTTTGTGGTCCAGAGAGAGGAAGA GGAGATCTGGATAAAACTGCTGAAAAATTTGGGGGCGGGGGTGAGGTGAAGAACCTAACAGTAAGTCTTG GAAGATGAAATACAACTCTGTTGATTACTGAAGGATGAACCAAATAACAGGACTGGGCCCACACAATAAA GAAGAAAAGAGGGCGGCTGGTTGTGGAGTTAAAGCAGAGAGAAGAAAAAGAAACAGCTACAGAAATTCCC CAAGGTGCAGGGTACAGGGCTGGGGAAGGTGCGAATGTTTGGGAATAAAAACAAACTTTGAAAAACAACA AAAAACAAGTCTTTTCAAAGCCTGGCCTCAGACTTAGGGTAAGTTCTCCCTGAGAGATTTAAAGGTAAAT AAAGAAGAAGCAAGTTAAGACTGAAAGCTTTGACTGATCTAACAGGAACATGTGGCATTATGGTTGTAAT GCCACAAATTTAGTATTTAGTATTTTGTGAAGTATTCACAAAGAAATGAACAGGATGCTGCATAATTTTT TACATTGTTTTCCAGGGGCATGTTGATGAGAAATGCTACTCCCTCCATTTTGTCCCCAGCATGTGTATGA TGAATAAGAAGAGGTGGGGGCGGGGGAGAGAGATTCTTCCCATCCACCAAATGCTACCCTGATTACCCAC GTCAGTCCTAACTCCTGCATTGCCCCAGGTGCCAGTCAGCAAGGCCTACGCCATTTGCTTTGCCATCTCC GCATTGTCCACTCACTTGCTCTGCCCTTCTGTCCATTTCACTGAGCTGGAGCTCCCAGCAGCAACTCTAG AAAAGAAGAAGAGGTGGGGAGTGGGGAATGGAGCATGCATGGATCTGGCAAGCCCCCCAGATCCCAGAAT CCAGTGAAAAGCCCCTCAATACACAGAGACATCAAGCTAGCTATCAAGAGTGCTGAACTAAGTCCCCAGT CCCACTGGGGCCAATGGTGGGGTGGAAGGCACCACCGGAGGCTGCAAAGAGCTTGGGCTTTGGAATCAGA TCTGGACTTGGCATCCCAGCTCTAGCACTTAGTAGGATGTGAACCTGGGAAGTAACTTAACCCTCTGAGC TTGGTTTACTTATCTGTAAACCAAGCAGTACTTAGCTCTCATGAGAGTGTTGGGAAGATAAGATGAGGTA ACCTGGAAGGACACCTGACACGCTGCAGGCACTTCATGAGTGTTCTATGCTACTGCCCATCTCTTCACAC TTGGTAGAAAATGAAAAGTGAGCTCTTTCAATGGTGAAAGCAAGTCCCACCTGCCTTCTTTTTTTTATTT TTTCATTTTTAGGTGCAAAGAGTAGCTCCTTCTGATGTTTCCTGGCTGTATTCTCCCTATTATGGTTGTA TTATCAAGTATGGAAAGAAAAACCCTGTTGGTGCAATCAGGTATGGGCGTATCTGACTGTGAATTGCCCA GATCAGCATCACACAAATACAAATTTGGATCCCGGACTTTGCACACCCAAAGCACTTCTTGATAAGATAG TGGAATGGTTAACAACTGTGATATCATAGTAAAACACAATTATTAAATGAGGTTGAATAGCCTTTGAAGA ATTATAAAACATTCAACAAGACCATAATAAGTGTCCTCAATATTCCTTGTTCCAGATAGAAACAACCCAC ATTTATGTTTTTGAAAATTTAATACTGAACACAACTCACCAACTAGGGGAAGGAGGAAAGCGTTCTAATG TCACAGAGAGCTTTGCCCTTTCTTCTAAAACTGTACTTTCTTCATAAGTTCTAAGCACCTTTGAAATGGT TCAAACAGGTATAAGTTACTGTGGAAAGGCAATGGAATAGAGAAAACCTTACCCCTTTAAGGTGGCTCCT AAGTTCATCTGATTCCAGGTCATGCATTCAAGCTGGGATGTCATTTGGTATAAATTGTCACTGTTAGAAA AACATCTAGAGTTAGAAACACATAACCACAAAATAATACACAACTGTTTCTTCAAAAGCAATGGAGTTTT AACTTTTCTTGAAAGTGCAAGCCTCCACATTTTCCAGAATGACAGAATATGCAAATCTGAATTATTTTCA TTTCATCCCACTGATCTCTGCACAGTTATACACTTCATACACAGCAGAAGGGATGTGAGAGTAACTCAGA AGCATTTTTTAAAACCTTTGTATAGCAACTATTGAAGTTTCTAAAGAAGTATTAAACCTTTGAGGGGAAA AGGCTAAGGGGAGTGAAACTTTGAAAGGCAACACAGGCTGGATAACTCAACATTAAAGTTAAAAGCCTGG AGCTGAAAGTAAAGACAGCAGATTAATTATTCGTGAAAAGGCCATTAAGTTGTTTTAATCAAAAGGATAA GTATCATGTGGATTATGAGGGTCTGAAAAGTCAGAGTGATGGGTGATAAATGGTCTAAAAAGCAAGGATG TGACAAGCAGAAGAAAGACGATGATAAACTCTATGCACAGCGGAAGGAATCATTTTCTATATGTTTTATA ATCCTGGTACAAGTCAAATTAAAAAAAAAAAAAAAGAGCCCAGTTCTATAAGACTCTATGAGGGAAATGG CTTATCATTTACATTAAGACTCCAAAGAAGTCTTACACCGCTATGTAAACCAACAAAAAGCTGTTCTGTC CCCTCTGTATTTATCTCATTCCTAGAAAATTAGCACATGAATCAATTGCCAGAAATCTCCTAAATTACCA AGCTCCATCAGGAATAAATTTATGCCTGAACTGAAATGGTTAATTATGAAATTTGAGACCCAAGAGACCA AGAGTTTTTCTGGGACCTCTTGGTCTAAACACTTTACAGAAGAAAAATTTCACTCTACCTTCATGGCAGA AATGAAAAAAGATAAGAGGCATTTAATATCCGATGTGTGGTATCAGATTGCAGATATAGGACCATCTCTG TCTGGTCATGGCATTCTTTTAAGCTGCTTCACTGGGCAGAGGCAACACCAAATTTTAATTCAGAAAGGCT TTTTTCAGGCCAAGCATAACTGGGAACTTGAGGAGGGGAGAGGGAAATTACAGCAACTCAGAATAAATGA ATTCTGTGCTCTCTGTCCGCATAGCGTGATAAATCATGGCAGAGTCCATCTGACTCTCATATAATAACTC TGAAAATTATTTGGAACTCCTTAGTGGTGGGTACACAGGATAAGGAGGAAATCAGATTCCAGGAGGGAAT TTTGCATATGAAAAGTGAAGTGACTTCAAACTCAAAGTATGTGCCGTTTCATTAGTCAGTGTGTATCTGG ACGCCGTCACTCATCCCCGTGTCTGACTGGCTATTATGCTACTACAATATCCTACATATCAATGAAAAAA AATGATGAGTTTCTCCTGCAGCTTCCCTGTTTGTAGCAGCAGCCCGTACTGGTCTGTGCCACAACATTTT GCAATTCCACAAATTCTTGCTGTAAGGCTGGAGTAATTAATTCCTGAAGGACCCCAACTTTTATTAGAAG TGCCAGCCTGCAGCATTTACCACAGGAGAGTTTCTTGAACTTTCTTTGGGCTGACAGTTCATTAATAAGC GGCCTCCTCCACAATCTCTCTACTGGTTTTTGTTCTCCTGCGCCTTTTCATCAAGCAATCCATTTATTAA TCTTACCATTAATCTCAGCCAACAGGCATTGTATTCCCCAGGCAGCTCTATATTTTTGTCACTAATTTTT TAAAAATTGTTCACCAACTAAAATCACTCAGCCCCAGTTGACAATTTTCCTAGGCCCTTTGGGGATATGG GATCTTTCTGAAATTATTTCATCCTTTCACAACTCAGAAAATCATAATTTTCAAGAGAACTGGGAAAGAA AGATGAGTGACAGACGCTGATGCAGAAGGGTGAATGAATCCCAAATATCTAACTTTATGAGTTGGAAATT TTCTCACAGACTTAAAGAATAGTCTGGTTGATTCCTAAGGTCTCTGTAAGGAAGTACCCCAAAGAGAAAA TAAACATTTTTTTCCGTTAGACGGAGTCTCACTCTGTCGCCCAGGTTAGAGTGCAGTGGCGCTATTTCAG TTCGCTGCAACCTCAGTCTCCCATGCGCAAGCAATTCTCCTGCCTCAGCCACCCAAGTAGCTGGGACTAC AGGCATCTGCCACCATGCCCGGCTAATTTTTGTATTTTTAGTAGACATGGGGTTTCACCATGTTGGTCAG GCTGGTCTCAAACTCCTAACCTCAGGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGAGATTACAGGCA TGAGCCACCGTGCCTGGCCAATATTTTTAATGGCATTTTCTTGGCCCTCAGAAGGCAAATCTTCTCAAAT ACAAGGTCTATGTCTTACGTATATGACTTTTTCTAGTGTGTACTGTACTGTCTAATATGGTATACACTGG CCACATGTGACTCATGCCACACATTAAAATGATAAGATTTTTTGCTATATTGAGTCAAATATGCTATTTG AAAAATTAATTCCACAGCTTCTTATTTTTTGAATGTGGTTACTAGCAAATTTCAAATTACATGTATGGCT TGTGTTATGTTTCTATTGGACAGTGATGTTCTATAAGTTTTGGGACATTGAGCAAATCAGTTCAGCTCCC TGCCCCTCAGTTTTCTCATCTGTTCAATGGGAATATTAATCTCCATCAGTCTAACTGTACAGAAATGTTG TGAGGCCCATAAAAGGTAATGCCCTCAATGGCCCTTTGAAGATGATACAGATAATATACTTTAATTACTT TAATTTGTTCTAACCTACCAAATTTTGCACAGCACTTTCACACATTCTCAATACTGCTCACAACTTTGTG AGGCAGATGTAATTCTGAGTCCCCATTTATTAGATGAGGGTTGAGGCACAGAGAGATGCCCAGTGCTGGC ATGCCTGAGCCCCCACCCTCACTCTGCCCTGCCCCTATGAAGGCATCCTGAGCCTCATCCTCTCATTACC ATTTATATAATAATAATAATAACAATAATACAGACAAGAGTCTGGAGGTGAAAGAGAATATGCTCAAGGG AGCATCATGACCTACTCAGTCTCTAGAAAATGACGATGCTGCAAGATGCCCCATGTGTCCTCTTCAGCTC ACTAAGGGCAGAGTGCCAAGATCCCAATAGAAGCCCCCTTTGCCATTCTAGCTGTCCTGATAGCTTAGCC TGCAAACTCTCAGAAGAGGAGAGAAGGTGGGGAGGATGTATGGGACAGAAGGACTTTCAGAAAATCCCCA AGCTACTAATAGGTTTCCTGAGGCCAGAGATAGGATCAGAGCACAGTTTTAACCACATCCTGCCTTTTGC TGGCTGGGGCTCCTCAGCTGCTCAGTCAGTGGGCCTGGCTGGCACGGCCTTTCAAATGGAAGTCAATGAC AGCAATGACAATAACGGCTGCTGGGGAGGGGACAAAAATGTGAACTGGAGCTAAAAATACTGGGCCGAAG CATGCTCAGGCTCTGATCTCTTTGGGCAATCGCTCAACACCCAGCTCTCATCATGGAAGCCCATGGAAAG AGGCAGCTTCGTTCAAGGAATATAGAGCCTCTGGCAAATGAAGCATCTAATTACTCAATAACCACTGTAG GTGCCACCACCTCATTCCCAGAGGAGATCAGATAAGCAGGTGGTTTGGCTTACAGCGACCACTGTGGTCA CGTAGGCATTTCAGCTCCAACCGTCTAACTCTGCCTGTTCGGAAGTGAACTTTCAAATTGCAGGCTGCCA AAATGTATTCCAAAAGTCATGGTGTCCTTTATATTTTTTAAGTAGATTTTTTTTAAAGTCACTTGTTTCC TATGTAAGAATGTTTGAAGTTGGAGGCAAAGGAAAGAGGAAAGAAACTTCTATAACTGGGATTAATGCAA GTTGGAGTAAAATAAAAGGAAGTCAGTCCTAGCAAAAAGGGGGAGCTTAAAAGGAAATCAGTAGTAGATC ATATAGAGTTTGTTTTGGCCTGAACTGCAGTATTATTAAGTTCTCGACCTCTGCACAAAAAGAAAGGAAG AAAAAAAGCCTCAGCTGTTATCTAGATGAGAACTCCTCCACTCTTCAAACGCATGTGTGATTCAAGCACA TTTTCATCTTTAAGTCTGTTTATTATATTCAGCAGAATAATTTGTGTCATCAAGGGAATAGAACCATCTA ACCTGGCTGAGATCAGGGTCACCTCTGCCACGTAGCTGCTGGCTGGCCAGGTAACATCTTGGAAGAAGTA AAGAGCTGCCCCCAGAGGATAAAAAATAAAAAGGCTCAAAGTAGACATAACTGGCATCTGTGATTAGAAT TCATGTTTCCAGCTTTTTCGGTAATAGCTGTGTCCCACACCAACAGAAAGGCCTCTGTGGGTGTACCTCT ACCTAATAACTTAACAGAGGGTGCAGCCAGACTTCCACACACCCTTTTCCTGTGCTCCTCCCTTTGAGGT GCTTTGCAGCCTGCCTGCCTAGAAATTTCTGCCCAGCAGGCCATAATGAATAATTATTTCACAGTCACTC TCTTGGTATTGTAATTTCTCTCAAGCTCACCAGCTAACCAAAGAAAAACCCACTGGGGATTCCATTTCTA TTAATAAACACTTGGTCAGCACAAAAGTTACAGGAATATTTGGAACTAGATTTTTCCTCCTCCCTGGAGA CGAGTTTAATTCAAGCCTGTGGCTTTGATAACATTGCCCATCACCCTGGAAGCCGTTTCAGACCTTCCAC CTTCTGCCTATCATTGCAGGAAACAAATATTGATTTTCTACTAAGGGAAAAGGCAGTGTACAATGTACAT AGGTACACAAGTGAAAAGAGGCATTATTAATTACAATTTTATTTTCTTGGGCATGGGCTGTCATCTGATT TCTGTCTATGTTGAAGGCCAACCCAAGTGGTAGATCGGCACTTCCCACTGAGTTATGGAACCCAAGATTT CCCAGAAACTCTATGGCTGCTGAGGAAGTTTCTCTCATATGAAAAATAATCTACTTGTAACAGGCTCCAC TGTCAATGTCACCATTTGTGAATCATCACATCCAGTTCAAAACAGACTAACATTGAATGATTGCTTCCAG AGTCGGAGTGGTTTCACCTGCTAACAGGCAAAAGTACAGCAAAAGGAAATATCTTCATTTAAATTCGTAG CACAGTTGCTAAAGAAGAATATGCAAACCTAATAAAAGAGCAAAAGGAAAGGGAAAGGGCTAGAATGCCT AAAAGAAACAATCAGTGTGCATGGGAATATTTTTCAAACGCAGTGCACAGAACTTTTCAAAGTAGCCATG AGGATCATATGTGAAGTCGGTATAGTCAAGGACTGGGGTCTCCGAGGAAGTCAGCAAAAAGATGAGGCAA AGGGACTCTGGGAAGGAAAGACAGCAGAAAAGGCCCAGCTAGCTGCCTTTTCTAGGTAGAAATTAGGGGG GAAATTGTGCCTAGTAAGGTTGGACCCCACTACTCCCTACACTGACAGAAGAACTTTTCCCTGGTACCTT CCCTCTGGGCAAGCCCAAACCAGGGTGGTCCTGGAAGCAGTCATTCTTTCTGGGTCTGGATGGACAGGGA GAAAGGTCTCTGCCCTGCAATTCTTTAGGTGCCTGGGCTGAACTTCACCCCAACAGTTCACACCCAGTGG TAAAGACAAAACTGGAGGAGTCTGGAGTTTGAAAGACAACTGCTCTGTGTGTTAGAACTTCAGGAGAATG CTCAAGCCTGCTTCTGATAATGGCCTTCAGGGAAAACGCTGTCCCAAACCACTAAGAACTTTCTGTTGAA AGCTACAGGTAAAACTAATGGATAACTGACTTCTTTCACAACTGTGGGAAATAGGAGACCATCCTTGAGT GAGACTGAGGACAGATGCCACCTTCACAAAGAGAATGGCACTTATCCATCTAGAGAGAAAGCAAGTGCAG AGGGTAGGAGGATGGATTCTGGAGCTGTATTGCCTGAATTTGAACACCACTTCCGTCCCTTAACTGTGTC ACACTGGGGAAATTTACTTCTCAGGGCCTGAGTTTCCTCCTCTGTAAAATGGCAGTGATAACCTGTTGTG TCCTTCAGAGAGTCACTAGGTAGATTAAATAAGTCAACACTTGTAAAGTGCTTACAGTGGTACCTGGTGC ATGTTAAGTCTACATAAGCATGTGCTCTTATGATTTATGAGCAAAAGTGATACATTGGCCTGGTGCGGTG GCTCACGCCTGTAATTCCAGCACTTTGGGAGGCCCAGGCGGGTGGATCACAAGGTCAGGAGTTTGAGACC ATCCTGGCTAACACGGTGAAACCCCCTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCACAT GCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCTCTTGAACCCGGCAGGCAGAGGTTGCAG TGAGCCAAGATTGCACCATTGCACTCCAGCCTTGCAACAGAGCGAGATGCCATCTCAAAAAAAAAAAAAA AAAAAAGTGATACATTGCCTATACAAGGGGAGTAATCAGATAGGGAATCCTGCGTGGTCTGGTGTCACTC AGTGATTCAGAGCACAGCTGGGCTGTGAAGTCAGAGAGACTAAGGATCAAATCCTGATTCTGATTCTCAC TTGCTGTGTGACTTTGAGCAAGTTACTTTGAGACTCTGAACTTAAACTAGAAATTATAGTACCTGCCTCA ACGAGTAGTCAAAAGGGTTAAATGGGTAAACTGAGTGAACCATTTAACGTCATGCACAGCAACATATAGT CAGCATGCAATAAATTCCAGTTATTACATTATAAGGACTCATGCTGTCATCCAACAATGATCACTGGGTT CCGTAAGGGCAGACACCTGGTTTCAGAAACCCTAGTGACCTTTACACAAAACTCCACCCACCTTGTATAT GAGAGGAGAGGGTAAGGAGGATAGAGAAAACCACCTCCTGTCATTTCCCATAAGTTGCTGATTGAATGTA TTTTCTATTCACTGTTGTTCATAGCCACAACAAATATATATGCAGCTGCAACTCCTCAGAACTGTCACCT GAGAGAAAGGAGGGAATTGTGCAGGGGACAAGGGAAGAACTGGGATTTTGAGAATGTCCTCAAAGCACAC TCCACACTGTATTTTGCTTATTTAATGTCAGATCTGTACCATTACCTTTCTTTAGACTGACAAGGGAAAG TATATCCAAAGACTGGGAAGAGGCCCAGCACAGCGGCTCACACCTGTAATCCCAGCACTTTTCGAGGCCA AGGTGGGCAGATTACCTGAGATCAGGAGTTTGAGACCAACCTGGCCAACATGGTGAAACCCCGTCTCTAC TAAAAATACAAAAATTAGCTGGGCATGGTGGCCAGCACCTATAATCTCAGCTACTTGGGAGGCTGAGGCA CAAGAATCACTTGAATCTGGGAGATGGAGTTGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGG CGACAGAGTGAGACTGTCTCGAAAAGAAAAAAAAAAAAAAAAAAAGACTGGGGAAGAAAAAGTTTGGTGA GGGAGGGGGAGAAAAAGCTGGGCAGTCAGCCTCAGAGGGTCAAATGCAACAAGGCAAACAAAATACAAGC AAGCTTTCCCCAGAAAGTCCCAAACTTTAGAGAGAAAAAATGAATGAAACCAGGGACCAGTAGAAGCACC ACTGAATACCTAAAATCCAAAAGTTAGGGTGTTAAGCAATTAAAGTTTAGTCCTATTTTTTATGCTTCTT CAACCATTACATTCACAAAAGCATTTAAATACCCTTTCAAACTTGTTTAGGAGTAGGAAAGAGGGAAACC ATATAACTGTAGTAATGTTGGTGCACAGACCCAGGTTTAAAACATTCCTACACCTGCCCATTCATCTTTA GACTGCAAGGGAAGCACATGATCTTTGAAAACTGAATGGAAATGTTAATTTAGAGTGAATGGAGCTTTCA AGATCCAGACAGCACAAATTCCAAGGGAACAAACTCTTCCTACAGGGGTCACAAATTCTTTTTTGAGATG TTACTACTTGGGAAATTTTCTGTGAGAGGGAAAAATAGTATTTTTATTGGATTTGTGTAAAAATAACAGG ACCAAAGAAAGTTCCTCAATTATAAAGAAAGAAGATAGAAATAAACAAATACTTCTGAAAGGTGAATTTG ATGAAGTGCTTAATACAGTGGCCAATCAGAAGCTGGATTAGAAAACGTGAAAATTTATGTGATGTTTCCT ACTTCCCTAGCAACCACAAAATCAGACCTAAGTCAAAATCCACCATAGGCACCCTGGAGAATTGCTATTA AACCAGTGGTAATGATCGCTTTTTCCTGGACTCCTCTTTCAAGGCTGCCAGGTCCTCTGATGGACCCCTT CCTAGGGTCCCACAGGGTGAGTCTCGGCTTGGGAGAGGGAAGTAACGGATGTGTGTGTAGCTTCGAGTCA CTGAGGCACCAGACTGCAAGGTCTTCCAGTCCCCAACCCCCAAGAACACCTCCCATATCGACAGTGCCCA CTCCCGCATCAAGGTCTTCTCTCAGCCTAGTGTGACACACCAACTGAGTCCACAGGGAGCTAAGGAGGAA GGGGTGGACCAAGGTCATTACGTGGGAACCATTCCAACAGCCCGCCTGATGGCTACTAGAATAACAGCAA TGACACCCTGGCAATGGGCAGGAGCAGCTACACAAGAAGAATGGCAATGGCCCCGCTGCCAGTTTTGCTA GGGAAGGAGATTCACCTCAGAGAATAGGTGCGAATCCTGCCCCCATTCCAAAGACTTTACCCACCGAAGG GAGGCGCTGAGGTGGCAGGCTTGGGGCAGCATGCCGCGCCTGTGGTGCAGAACAGGAATGATTTCTAGCT AGGGACGCAGAAAAAGAAGGATGGGGAGGTGCGACCATTGGTGTTCTTGCCCACCGCCTGCCTCCACCCG CCCAAAAAAAGTGTGATGAGGAATCCAAGTTTCGAATAGATAAACCGGATGTTCCGGGGGAAAAAAAGGA AAAAAAAAGGTTTCTCCAGTCCGCGCGCCTCAGGCGTTAGAAATAGAAGGGGCGCATCCCTGCACCTCTC TAGAAACTCCCGGGAAGGAGAACCTTAGATGCGAGAGCCAGGCCAGCCCCGGGCTCACTCTCGTAAAGGC AGCAAGGGCCTGGGGCTGCGCCTCGCTCCGGATCGAGGACTCCCGCCCCTCCTCCACCTGCGGGACTGGA CAGTCCCCCAGGCGCGGCCACTCCCCCACCCAATCTCCCAGGGCAGGCGCTTTTCCTTCCTTCATGACCT CACTACCTCCTTCCCTTGACGTCAGCCCCGGGTCCCCGCGCGGAGGGGAGGGAGGATGGGGATGGGTTTG GGGGCAGCCGGTGTCAGGATCCCCGAGCACCAGGGAGGAGGGGGCTATGAGGTCATGCGCGCCCAATCCC GGGCCGCACAGGCCTCGCGCTGCTGCTCCCCGGCCCCCGCCCCAACTTCCAGCCCCGTGCGGGCTGGTGT GCGCCGCAGTTACTAGGCAACCCTATCGCAGACGCGGGCGGCCGGCCAAGTTCACCCAAAGTTGAAGAAA AAATTTGGGGGAGAGAAGGTGGAGCGAGAGGCGAGAAGAGGAAGCACGGAGCGGGGAAAAGCTTGGAAGG GAATGAAGCTGGCCTTGGGCCTCCCGCTCACAGGAAGAAGGTCCCACGCGGGCCAGAGCAGCCTCCCCGC AGGGCCCTGTTGCGACCCGATCTCCGTCCTGCACCCCGGCCGGGGGCCCACCCCAGAGCGTAGCAGGGGC GCTGGGAACGACGTCCACAAAGCGCTGCCACGGGTCGAAACCCTGGAGGGTTGAGGTGGGGAGAAGGCTG TGGCCAAGGCTGTGGCCGAAGGTACGCGCCTTCGAGGTAGTCTGGCCGGTGTGGCCATTGGATGGGTTTG AGGTCTCAGAACCGAGTGGGAGTGGACTCCGTGTTTAATATTTAGTCCCGATGAAGGTAAATTCCTCCCA GTAAAGACCTTCTAAAAATAATAACTTCTCGAGCGCCGCTCCTTCTTCAGCTCGAAAGAGTAATTGTCCT CATTTTTATACAACATAAGAACAACTCAGAGACCAGGGAGATCAGCTTTAATTTCCTCTAAGTAGTAGAG TGGAGTCGAGGCGTCTCGTGCCTCCAAGACCCTGCATGCCCGCAGTCAGGGCTGCCCGGCTGGGGCGTTC CCAAGTCCGCCGGCTCATGCGTCCCCTCCGGGGTCCCAAGGACCCAGACGCAGAGCCCAGCGCCTTCCTA CCTGCTGTAGGGCGTCCTCAGCAGCAAAGCCTGGCTGCCGGTGCAGCTGTCGGTGGGGGTGTGGCAGCCA TAGACCGGGGGCGGCACCGAGTACTGCTGCTCACCTGCAGAGAGAACCGAAGACAGCTGAGCGAGTGCGC CCCAAGGGCTCGGGGTGCGAGGCTGCGGGCAGGGGTTGGGGGAGACACGAGATCCTGAGCCTGGGGCACT GGGGCCTGGATGAGCGGCGTGCAGAGCGAGGCCGTCCAGAATGCAAGAAGCTAAGCCTCTCACTTTGCAT TCCCCTAGCAGTCGCTGCGCTGTGCACCAAAAAGGCCCTCCGGACATTCATAGACTTAGTTGGATGGCGA TGTCCCTAACGTACTTGGGATGGAGGGAGACCCAGTCTTGTCCTTTAAATACAGTGCCATTGGGGTAATG ATTTCTAAGGTCCTTTTAGATGTCCTCCTTTGCCTAATTTGCTGTGGGTTAGGAATTCCTGGGGGAGAGG AGGATAGCACGGAAGAAGGGGAGAAGGACTCCACTTGGTTCCGCTCGCTTACCCAGCGAGCCCTGCTGGC CCATGGGATCCTCATGCTTGAATGAGTGGTTGGGGAACTGCGCCGCATGGTGCGAGGGCGTGTGACCGTA GCTGGGCGTCCCGTCGAAGGTGACCGTGCTGTAACCTGCGGGAGCGGCGGAGAGAAGCACAGTGTCAGCG GTGCTCTCGCAAGACGGGGCAGTGGGTCTGAACCAGCCACGGGCGGGGGGGGTGTGCGCTGAACCCCGCA TTCGGACCCCCAGCGGAGGAGAATCCAGCCCCACAAGCCTCCAGGACTTTCGGCAGGAAGACGGCCCAAG TCCCTGGATGTGACCTTGGGACAGGCTTCTCCATCCTTTTCTGACTAAAACCCCCACCTCGCTTTTTCCC AATTTATTTATGCCGCAGTCTTCTACGGTCTCTGCCGCTTCTGCAGCGAACCCCTGGCAAATTAAGTATA AAACTCGTTGCCTGATCGACAGAGAAGGTTGTTCACCCCCCAAAAATAAACTGCAGCTCTTCCGCAGGAG CAGCGCGGGCAAGCGAAATGAATCTGCTGGGCTAACCCCGCGTTGACTCCGAGCTGTAAATCAGGGGCCC GCGCACCAACTTTCATTAATTACTCGGAGCCAGTTAAATGGCCTGGTCTTAAAAATGGGAAGAGTAATTA CCGAGTAATGTTATCTGTCTGGGGCTACCCGACCTGACACCATGACACCCAAGGGAAAGCTGGTGAGGGG GAAAACAAGGGCCCCTTCCAGTTGGGCCTTCAGATGGCGACCCTGCGCTCTCCTCCTCCTCCCCCCTATG GGACCCACCTTGCGCCCAGGGGTCCGACCCTGACCACTGCTGTAGGAGCCAACTTCCTCACTCCCCAGGC TGGACAACCAATTTCCTTTAGAGTGTGCCTGACACTGTATCTCCCTTTCCCTCCATGGTAGTGCTTCGGT CCTTTGCCTCAGTTTCCCCCTAGGGAAATCCTAGCATTCCCCCCCCCCCCCAAAGTGAGAAAAAGAGCGT GGAGCCTCAGTTGGAAAACATAGTCTTTTATAATTTTTGTTATTAAATTGCTTTAAACTTATACCCCACA AGCTTCTGGAAAGCTGTTGCTGCCTCTGGGGAAAAGGATCCTTCGGCTAAAGATACGTCATTGGCCCCGG AACCCAAGGATGGGGTCTCATTCCTCTACAAGTTCCGGAGTCTGTGGCCTGAAGTCCAGACACAATGGCT AAGGAGAGCTGCTCCTATGGGATCCTGGCAGGGCCACCCCAGCAGCCTCAGATCCTCCTGGCCCAGGACT GCCCTGGGTCTCCAAACTTCACAAAATTCTCAGGAGTAAATTGGGTCAAACAGCACCCATTCTCCCACTC TTGCACTATTTGACCAAAGTGCCTCCAAAGACTTAAGCAGGACTCAGCCGATGAGCAGGACCCAGGGCAT CGTTACCTCCATTTTCGAAACACACACGGACGCTCATGCACACACACCACCACCCCCCGCCCAGAAAAAA AAAAAAAGAAAAAGAAAAAAAAAAAGCTTCTCTGGGGCAACAGAGGCATGAGCCTGGAGGGTGGTGTGGC AGAGTGCAAGGGAGGGAAGGAGGGGGCAAATCCTAACTCCCGGATAGTACAGGTCCAGGCTTAAGTCTCA CACACTGCTCAGCACCACACACTGGGGATTTGAGAAGCCACTAGCTTTTATCATATGACCTCGAGGGCCT CCATTTCTCTCCTGCTAAGTGGGCAAAGATAACCCCCGGCCCCGTTAGCTCTCCTGCATGGGCGAGCACG TTTGGGCTTCCACAGACTTCCTTTTGAAACCTGAGGCCTGGCCTTCTTTGAGGCCTATAGATGAGCTTAC AAACGAAATTTGGCTCAGGGCACCCACTATTGCCCGGAGTGAAGGCCGAATTTCTGAAAGGACACTAAAA AGAGAGAGAGAGAAAGAGAGACAGACACAGAGAGAGAGAGAGAGAGGGAGGGAGAGAGAGAGAGAGAGAG AGAGAGAGAGAGAGAGACGAAATAGAAGCTACGAAGAAGTTTTCTCTAGACGAACCCTTCTCCATTCCTG AGCCCAGGAGTAGGCAGGGACCCAGGGCACTGCACAATCCTCAGAGCCCTGCTCCGCAACTGTCCGTGCC CGGCGAGGGCCGTGGGTCCCGAGTCGCGGCACCCACTCTCGAGACGTCCGTCCGCACCCCAGAACTCGGG CCCAAGGATGCCCGTGGCCCGCGAGCCCTCCTAGGCCTCCTCCCAGACCGGACACGCAGACCTCGGCGGG CAAAGACCGGCCTCAAACCCTCTCCTTCAGGTCCCCCCGGGAGGGGCAGTGGTGAAAGCGCCTGCGGAGC GGAGGGAGGTCTCTTTTAATTAGAAGCTTATCGGACACGGGTTTGATTAGAGCGCGCTGTCCCTGGGCCC AGCGCTTGGCCTGGCGCGGAGAGTGCGGGGGCAGGGGCCAGGGGAGGTAAAGCTGCCGGCTGGAAGGAGC AGCGTGTTCAAAGGCTCCTTGTACAGGCCTTGGAGGGAGAGAATCGAGTGGCCAAGGTAGCGCCTTTCCC ACGGTTAGTCCCGGCCCGGGAGGGGAGCGCAACCTTGACCGTGCGCTAAGAGGCGAGACGCGCTCTGTGC CCTCCTCCCCCGCCGGCGGCTGCAGAGAAGCCGGGAACCGCCTGGCCTGGCCGGGCCGTGAGAGCTGAGG GGTGAAATGGACAGCAGGCTCAGCCAGGAAGGTGCTCAGAAGGCTGAAAACGATGACTGCAGCTGCACTG TGATTGGGGAAAACCTGTCCCCCAACAAAATACCCTCTCCTGTGTGACCGGAAGAGGGAGCCTTTGGCCC TCGGGCGTCGCAGGCCTCCGCACCTGACCCTAGGGTGGCCTGATGATCCCAGGCCTAATCATGCCTTAGG GTTCTGCGAGCCTGCGGGGCTGCGGGATCAGTGGACTAGCAGGCAACCTCTTTTTTTTTTTTTTTTTTCC GAGACGGAGTTTCGCTCTGTCGCCCAGGCTGCAGTGCAGTGGCGCGATCTCAGCTCACTTCAACCTCAGC CTCCCGGGTTCAAACGATTCTTGTGCCTCAGCCTCCCGAGTAGCTGGGATTATAGGCGCCCGTCACCAAG CCCGGCCAATTTTTTTTTTTGTATTTTCAGTAGAGACAGGGTTTCACCGTGTTGGCCAGGCTGGTCTCAA ACTCCTGACCTCAGGTGATCCAACCGCCTCGAGCCACCGCGTCCGGCCCAAGCAAGCTTTTTTCCCCTCC TCCTTAAGCCTTGCATCTAGTCTGGGGCTACTCAAGTCCTCACCCCACATCTGCCCTCACAAACCCGTCA ACCCCCACACATGGACTAAGAGTTTGGTGCCCCTCCCGCAGGCCAGAAGAAATCCATCTCAACGGTGGGG CCAAGATCCCTGGAAAAGGAGTAGAAACACCCTAGCATGGTCTGGGTTCAAATCCCACCTCTGCCACCTA ATCTCATAGAACCTGGATTTCCTCATCCAAAACAAGGGGCCTCTCCAGGATTAGCTGGTGAGCTTCTTGC AAAGGTTCTCGAGGCCATTGTCTTAATTAATATTCAGAACCCAGTGCCTGACCAAGTAGGCGATTGATGT TTGCTAAATTAATGTTTACAAGATTAGGATGCAAGATATAATATTTAAGAATTTAAAATATGAACATGCT TGTGAAGTTTTGGGCGGTTGTGAGTGGGTACCAACAATTGCCCCTGCCTGTGCACCATGGCTAGACTGCC CTAGGGATCCAGAGACGGCCTTGATTCCTCTCCCCTGGGGTTTGGCCTTGGCGCTCTGATGGCCATTTCC ACATTTTTGAGAGTTGATGCCCTTGCCTCTCACAGCCCAAGTCTTGGGCCAGGCCCTGCATTCCTGGGGA AGCAGCAGGAACCCTGGAAATCCAAAGAATAAACCCAGAATCTCGAGGGCCACCCTTGCCCACTCCAGGA TAGCAGCCGGAGCGCTTCTCACATCCAAGCTGCCCAATGAGCCTCAAGGGCTGGGTAAGATGGACCCATC TGTTTTCACTGCAAGACAAAACTTAAACCTGGAGATGGTGCTTCCAGGCTATATGACTTGAATCTAGGGC CCTCTCTCCATTGGGCTTTTTCTCCAGGGTGGAGAAGAAGGATACATTCACCTACTAGTCCTGGTCCCCT TTTAACTTTTTCTCCATGGCAGCCACGCCTGTATATTACAGAAGAATCCAGATATTTTCCAGAAGTGTAA TGCCTGCTGGCTGCAAAACCCACAGTCCCACCCCCCACGACATGTGATAAGATCCCAGGCACCAGACCTG CCCTGAAAAGGGCTGGACAAGGGACCCAAACGAAGCGACAGAACCCAGGTTTCAAAAATCCCCTAGAAGT ACTAAAAAGATAATGGCGTAGTAGTATTTTGTGCCCCAGGGGCATGGATTCGATGGTTTCTCAACCGCCT CCAAATAGCACACATGCAGACAGTGCTCTCGGATTCATTGTTTCTCAGTCACAGATGTTTAGATGGGTTG CCGAGTTCCATATTTAAAGCCCCAAGAGGGTGGTGGGTAGCGCTTCTGCATCTATGGAGTATAACTTCAA GCCGGACCCAATCTCCAGGTTGCCCATCTCAGCTGTCCTCTTATAGACGGGGACACTGAGACCTAGAAAC TCCCCAAAAGTAACACCAGCCTGCTAAACAAAGGTGGCGCGATCTGATCAAAGAACACAAGCCTCAGCGA CCAGTAAGTTGTCCCAACGCCCCTTGAGTACAAAACACTAATTTCACTAACTAAAAGCATAGAGTGGAGG CAACCCTTGGGTCTGCTTGCGGTTCCTCCACAGGACAGTGATCCCAGATTCTCCCGAAGAAAAGGGCGGT TTCGATTTCTCCAAGGCTTCGCGGGGGCCGGGTGCTCCTGGTTAGGCTAAGGTAGGAGCGGCCTGAAGAC GCGCGTTTAGAAGGCGCGGGTGAAGGCGGGCAACAAGGGCAGAGCCCTTCTCCCGAGCCTTGGGCGAAGG TACCTCCTGCAAAAGATACACTCTGCTTCCCACGCATTCCAAAAACATCCCGGTCCCTAGGCCCTCGAGT AATTTTGCTCCAGGAAAAGCATCCGCCATTGTATTAGTAAAGCGTTTACTAAATTACCGAATCAAACCGA ACTGGCTTAGGTTCTCAATAGCGTGGAAATCCACTGAAAATAAATGAAGAGGGCAAACTACAGGGGCTCC GCAGGTTCGGGTCCGCGCCGCCCAGGCGAAAGAGAGGTGGGCGGGCATCGGCGCGGGATGAGAAACCAAC CTGATACTTATCGTGTGCCGAGTTCCCTCCTTGTATCCTGACTAAGCACAGCGAATAACCCTGTCCTTGT TCTAACCCCAGGTCTTGAAGAAATACTGTCCCAGCTGAGCCCCGCGTTTACAAGATGAAGAGGCGCCCCA GATGCGCTGAAAGAAAGGCCAAAGCTCGTGCCTCCTTCCACTGCCTGCGGTAGAACCTGGTCCCGCATAG CTTGGACTCGGATAAGTCAAGTTCTCTTCCATCCCCAGAACCTGCGTGGCCGCCGCCTGAGCGAAGCCCA GTGAAGATCCACTTCTGTATTACCATACGCGGGAGCTATCCACGGACACGACGCTGTTCCAGAAAGCCAT TTAGTTACTGGAGGTGCATGTGCTCATTCTAGTTCTCTACGATACTTAATGTGCACCTAAGTGTGTGCCA ACACCGTATTATAAGGGCTGGAGGTGCTCCTGGACATTTTAGCGCTGCGGAGGCAGCACAGCACAGGCGC TCACCCCCGCGCTGGTCCCACTCCGAATCCAGAGTCCAGACGTCTGAAAAGCGCTACGCTTGGTGACAAT TTGGCGTTTCCTTAATTAACAAAACTCTCCCCAAGGCAGAGCCAGACACTGCGCCGGTCTCCTGGTTCCA CTCCCGTGGGGACTAGCAGTCCCGGAATCTCTCGGACTCTAAGGGGCCCCAGACGCCCTCCCGGCTCTTG CGAACAGTCAGGCTCCTAGCTCTGCCTGGCTTTGGAGGATGTCGGGGGCCAGTGCCTGCGTGCACTCCCA CTCTCCGGCCTCCTCCCCAGCCGCCGCTTCCGCTATCCTCACGGCCCTTGGGAAGCAGCTGGGTAAGAGC TGCGGTCAAAAGGGGTAGGAGAGGGGGGTGTCCTAGAGCGGAGAGTCCCTGGCGCCACTGCCCCGCGCGT AGGGGGCGCTCCCCGGCCTACTTACCCTGATTGCGAATAGCGGGCTGGCTCTCGAGGCAGCTGGGCAGGT AGGGCGCGTTAGGAAACATCCTGGCCTGGCCGGATGACGCCTGGCTGGGCGGAGGAGGACCGAAGGGCCC GTAGCGACAGGCTCCGGCTGTGCCAGTGAACTGGCCGGAAAAGTGGACAGTGAAGGCGCTCAGGCACTGC TCCTCGTGCGGCTCCGCGCCGCCCCAGCTCGGCTCCTGTTTGATGAAGGAGTGAGGCGGCGGCGGCGGGG GTGGCGGCGGAGCCGGTGGCGGCGCGGGGCCGCCCAACGACCCGTAAGCCGAAGCGCCCGGGGGCGCAAA GTCCAGCACCGGCGCCCACTGCGCCGCGCCGCTCACAGGCAGGGCACAGCCGCCGCCGCCACCCAGGGAG GGGACGGCGGGCAGCAGCGCGTTCAGGTCCCGCACGTCGGAGCCCATTTGCTGCGGCTCAGACCCGGACG CCCCGCGGCTCCTCCGGCCCTGGAGACGTTCAGCGCTGGCCTCGGCGGCGCCTAACTTGGCCCAGATGCC GCCCGGGTCCCGGACTCCCTGCTGCTCTGGCTGCTGTAGGCACCCAGGCCCGGAGCGGAGCGTGTGCTGA GACGCCGGCTCCGGGACACACGTGGAAGCCGGGTCCTGCAGCAAGAGGAAGTCCAGGATCGCGGCGAGGA GACGGCGGGGCCCGGGCGCCTGGGCTGCCGTCCCGGCTCTGGGTGGGTGGGTGGGTGAATGAGTAGGTGG GAGGGAGGGCGGGAAGTGGGGGAGCGGACAGGCGGTCGGGTTGCGGAGAGCCCCCGGGTGTGGGCGCTGC CTTGAACTCCTTACCCCAGCTGCCT
Protein Name	WT1_HUMAN
Length	449
Moltype	AA
Topology	linear
Division	PRI
Update Date	12-OCT-2022
Create Date	01-FEB-1991
Definition	RecName: Full=Wilms tumor protein; AltName: Full=WT33
Primary Accession	P19544
Accession Version	P19544.2
Other SeqIDs	sp\|P19544.2\|WT1_HUMAN,gi\|139778
Organism	Homo sapiens
Taxonomy	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Comment	On or before Sep 25, 2009 this sequence version replaced gi:74754043, gi:74754044, gi:74754045, gi:482301.; [FUNCTION] Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed:7862533, PubMed:17716689, PubMed:25258363). Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PubMed:15520190). Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed:16934801). Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed:19123921). {ECO:0000269\|PubMed:15520190, ECO:0000269\|PubMed:16934801, ECO:0000269\|PubMed:17716689, ECO:0000269\|PubMed:19123921, ECO:0000269\|PubMed:19416806, ECO:0000269\|PubMed:25258363, ECO:0000269\|PubMed:7862533}.; [SUBUNIT] Homodimer. Interacts with WTIP. Interacts with actively translating polysomes. Detected in nuclear ribonucleoprotein (mRNP) particles. Interacts with HNRNPU via the zinc-finger region. Interacts with U2AF2. Interacts with CITED2 (By similarity). Interacts with ZNF224 via the zinc-finger region. Interacts with WTAP and SRY. Interacts with AMER1. Interacts with RBM4. {ECO:0000250, ECO:0000269\|PubMed:11001926, ECO:0000269\|PubMed:12239212, ECO:0000269\|PubMed:12970737, ECO:0000269\|PubMed:15518539, ECO:0000269\|PubMed:16934801, ECO:0000269\|PubMed:17716689, ECO:0000269\|PubMed:19416806}.; [INTERACTION] P19544; Q92997: DVL3; NbExp=3; IntAct=EBI-2320534, EBI-739789; P19544; Q6A162: KRT40; NbExp=4; IntAct=EBI-2320534, EBI-10171697; P19544; P60410: KRTAP10-8; NbExp=3; IntAct=EBI-2320534, EBI-10171774; P19544; Q6N021: TET2; NbExp=9; IntAct=EBI-2320534, EBI-310727; P19544-6; P05067: APP; NbExp=3; IntAct=EBI-11745701, EBI-77613; P19544-6; O14503: BHLHE40; NbExp=3; IntAct=EBI-11745701, EBI-711810; P19544-6; P28329-3: CHAT; NbExp=3; IntAct=EBI-11745701, EBI-25837549; P19544-6; A8MQ03: CYSRT1; NbExp=3; IntAct=EBI-11745701, EBI-3867333; P19544-6; P25685: DNAJB1; NbExp=3; IntAct=EBI-11745701, EBI-357034; P19544-6; P22607: FGFR3; NbExp=3; IntAct=EBI-11745701, EBI-348399; P19544-6; Q6NT76: HMBOX1; NbExp=3; IntAct=EBI-11745701, EBI-2549423; P19544-6; P01112: HRAS; NbExp=3; IntAct=EBI-11745701, EBI-350145; P19544-6; O15397: IPO8; NbExp=3; IntAct=EBI-11745701, EBI-358808; P19544-6; P60371: KRTAP10-6; NbExp=3; IntAct=EBI-11745701, EBI-12012928; P19544-6; P60409: KRTAP10-7; NbExp=3; IntAct=EBI-11745701, EBI-10172290; P19544-6; Q9H4L5: OSBPL3; NbExp=3; IntAct=EBI-11745701, EBI-1051317; P19544-6; P16284: PECAM1; NbExp=3; IntAct=EBI-11745701, EBI-716404; P19544-6; Q9NRD5: PICK1; NbExp=3; IntAct=EBI-11745701, EBI-79165; P19544-6; Q13501: SQSTM1; NbExp=3; IntAct=EBI-11745701, EBI-307104; P19544-6; P37173: TGFBR2; NbExp=3; IntAct=EBI-11745701, EBI-296151; P19544-6; Q15007: WTAP; NbExp=3; IntAct=EBI-11745701, EBI-751647; P19544-6; Q9UGI0: ZRANB1; NbExp=3; IntAct=EBI-11745701, EBI-527853.; [SUBCELLULAR LOCATION] Nucleus {ECO:0000269\|PubMed:15520190}. Nucleus, nucleolus. Cytoplasm {ECO:0000250}. Note=Isoforms lacking the KTS motif have a diffuse nuclear location (PubMed:15520190). Shuttles between nucleus and cytoplasm. {ECO:0000250, ECO:0000269\|PubMed:15520190}.; [SUBCELLULAR LOCATION] [Isoform 1]: Nucleus speckle {ECO:0000269\|PubMed:15520190}.; [SUBCELLULAR LOCATION] [Isoform 4]: Nucleus, nucleoplasm {ECO:0000269\|PubMed:15520190}.; [ALTERNATIVE PRODUCTS] Event=Alternative splicing, Alternative initiation; Named isoforms=8; Name=1; IsoId=P19544-1; Sequence=Displayed; Name=2; IsoId=P19544-2; Sequence=VSP_006866, VSP_006867; Name=3; IsoId=P19544-3; Sequence=VSP_006866; Name=4; IsoId=P19544-4; Sequence=VSP_006867; Name=6; IsoId=P19544-6; Sequence=VSP_037582, VSP_037584, VSP_006867; Name=7; IsoId=P19544-7; Sequence=VSP_037583; Name=8; IsoId=P19544-8; Sequence=VSP_037583, VSP_006866; Name=9; IsoId=P19544-9; Sequence=VSP_037582, VSP_037584, VSP_006866.; [TISSUE SPECIFICITY] Expressed in the kidney and a subset of hematopoietic cells.; [DOMAIN] Binds to DNA motifs with the sequence 5'-GCG(T/G)GGGCG-3' via its C2H2-type zinc fingers. Starting from the N-terminus, the second zinc finger binds to the 3'-GCG motif, the middle zinc finger interacts with the central TGG motif, and the C-terminal zinc finger binds to the 5'-GCG motif. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Has reduced affinity for target DNA where the cytosines have been oxidized to 5-hydroxymethylcytosine, 5-formylcytosine or 5-carboxylcytosine. {ECO:0000269\|PubMed:25258363}.; [DOMAIN] The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. {ECO:0000269\|PubMed:31375868}.; [RNA EDITING] Modified_positions=281 {ECO:0000269\|PubMed:7926762}; Note=Partially edited.; [DISEASE] Frasier syndrome (FS) [MIM:136680]: Characterized by a slowly progressing nephropathy leading to renal failure in adolescence or early adulthood, male pseudohermaphroditism, and no Wilms tumor. As for histological findings of the kidneys, focal glomerular sclerosis is often observed. There is phenotypic overlap with Denys-Drash syndrome. Inheritance is autosomal dominant. {ECO:0000269\|PubMed:10571943}. Note=The disease is caused by variants affecting the gene represented in this entry.; [DISEASE] Wilms tumor 1 (WT1) [MIM:194070]: Embryonal malignancy of the kidney that affects approximately 1 in 10'000 infants and young children. It occurs both in sporadic and hereditary forms. {ECO:0000269\|PubMed:1317572, ECO:0000269\|PubMed:15150775, ECO:0000269\|PubMed:9108089, ECO:0000269\|PubMed:9529364}. Note=The disease is caused by variants affecting the gene represented in this entry.; [DISEASE] Denys-Drash syndrome (DDS) [MIM:194080]: Typical nephropathy characterized by diffuse mesangial sclerosis, genital abnormalities, and/or Wilms tumor. There is phenotypic overlap with WAGR syndrome and Frasier syndrome. Inheritance is autosomal dominant, but most cases are sporadic. {ECO:0000269\|PubMed:10738002, ECO:0000269\|PubMed:10799199, ECO:0000269\|PubMed:11182928, ECO:0000269\|PubMed:11519891, ECO:0000269\|PubMed:1302008, ECO:0000269\|PubMed:1338906, ECO:0000269\|PubMed:15349765, ECO:0000269\|PubMed:1655284, ECO:0000269\|PubMed:8111391, ECO:0000269\|PubMed:8112732, ECO:0000269\|PubMed:8295405, ECO:0000269\|PubMed:8388765, ECO:0000269\|PubMed:8411073, ECO:0000269\|PubMed:8741319, ECO:0000269\|PubMed:8956030, ECO:0000269\|PubMed:9475094, ECO:0000269\|PubMed:9529364}. Note=The disease is caused by variants affecting the gene represented in this entry.; [DISEASE] Nephrotic syndrome 4 (NPHS4) [MIM:256370]: A form of nephrotic syndrome, a renal disease clinically characterized by severe proteinuria, resulting in complications such as hypoalbuminemia, hyperlipidemia and edema. Kidney biopsies show non-specific histologic changes such as focal segmental glomerulosclerosis and diffuse mesangial proliferation. Some affected individuals have an inherited steroid-resistant form and progress to end-stage renal failure. Most patients with NPHS4 show diffuse mesangial sclerosis on renal biopsy, which is a pathologic entity characterized by mesangial matrix expansion with no mesangial hypercellularity, hypertrophy of the podocytes, vacuolized podocytes, thickened basement membranes, and diminished patency of the capillary lumen. {ECO:0000269\|PubMed:11182928, ECO:0000269\|PubMed:15253707, ECO:0000269\|PubMed:20798252, ECO:0000269\|PubMed:9529364, ECO:0000269\|PubMed:9607189}. Note=The disease is caused by variants affecting the gene represented in this entry.; [DISEASE] Meacham syndrome (MEACHS) [MIM:608978]: Rare sporadically occurring multiple malformation syndrome characterized by male pseudohermaphroditism with abnormal internal female genitalia comprising a uterus and double or septate vagina, complex congenital heart defect and diaphragmatic abnormalities. {ECO:0000269\|PubMed:17853480}. Note=The disease is caused by variants affecting the gene represented in this entry.; [DISEASE] Note=A chromosomal aberration involving WT1 may be a cause of desmoplastic small round cell tumor (DSRCT). Translocation t(11;22)(p13;q12) with EWSR1.; [DISEASE] Mesothelioma, malignant (MESOM) [MIM:156240]: An aggressive neoplasm of the serosal lining of the chest. It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. {ECO:0000269\|PubMed:8401592}. Note=The disease may be caused by variants affecting the gene represented in this entry.; [MISCELLANEOUS] Presence of the KTS motif hinders interactions between DNA and zinc-finger 4.; [MISCELLANEOUS] [Isoform 1]: Detected in nucleus speckle, may bind mRNA.; [MISCELLANEOUS] [Isoform 7]: Produced by alternative initiation of isoform 1. Extended N-terminus. {ECO:0000305}.; [MISCELLANEOUS] [Isoform 8]: Produced by alternative initiation of isoform 1. Extended N-terminus. {ECO:0000305}.; [SIMILARITY] Belongs to the EGR C2H2-type zinc-finger protein family. {ECO:0000305}.; [SEQUENCE CAUTION] Sequence=AAB33443.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part.; Evidence={ECO:0000305}; Sequence=CAA35956.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; Sequence=CAA35956.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical CTG leucine codon.; Evidence={ECO:0000305}; Sequence=CAC39220.3; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; Sequence=CAI95758.2; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; Sequence=CAI95759.2; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}.; [WEB RESOURCE] Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL='http://atlasgeneticsoncology.org/Genes/WT1ID78.html'.; [WEB RESOURCE] Name=NIEHS-SNPs; URL='http://egp.gs.washington.edu/data/wt1/'.
Source Db	UniProtKB: locus WT1_HUMAN, accession P19544;; class: standard.; extra accessions:A8K6S1,B3KSA5,Q15881,Q16256,Q16575,Q4VXV4,Q4VXV5,Q4VXV6,Q8IYZ5; created: Feb 1, 1991.; sequence updated: Aug 1, 1991.; annotation updated: Oct 12, 2022.; xrefs: X51630.1, CAA35956.1, M80232.1, AAA61299.1, M80217.1, M80218.1, M80219.1, M80220.1, M80221.1, M80228.1, M80229.1, M80231.1, X61631.1, CAA43819.1, X61632.1, X61633.1, X61634.1, X61635.1, X61636.1, X61637.1, X61638.1, AK093168.1, BAG52667.1, AK291736.1, BAF84425.1, AY245105.1, AAO61088.1, AL049692.13, CAC39220.3, CAI95758.2, CAI95759.2, CAI95760.1, CH471064.2, EAW68220.1, EAW68223.1, EAW68224.1, BC032861.2, AAH32861.1, M30393.1, AAA36810.1, S75264.2, AAB33443.1, S61515.1, AAB20110.1, S61522.1, AAB20111.1, S61524.1, AAB20112.1, S60755.1, AAC60605.1, A38080, NP_000369.3, NP_001185480.1, NP_001185481.1, NP_077742.2, NP_077744.3, 1XF7_A, 2JP9_A, 2JPA_A, 2PRT_A, 3HPJ_C, 3HPJ_F, 3MYJ_C, 3MYJ_F, 4R2E_A, 4R2P_A, 4R2Q_A, 4R2R_A, 4R2S_A, 4WUU_C, 5KL2_A, 5KL3_A, 5KL4_A, 5KL4_D, 5KL5_A, 5KL6_A, 5KL7_A, 6B0O_A, 6B0O_D, 6B0P_A, 6B0P_D, 6B0Q_A, 6B0Q_D, 6B0R_A, 6B0R_D, 6BLW_A, 6RSY_C, 6RSY_H, 6WLH_A; xrefs (non-sequence databases): CCDS:CCDS55750.1, CCDS:CCDS55751.1, CCDS:CCDS7878.2, PDBsum:1XF7, PDBsum:2JP9, PDBsum:2JPA, PDBsum:2PRT, PDBsum:3HPJ, PDBsum:3MYJ, PDBsum:4R2E, PDBsum:4R2P, PDBsum:4R2Q, PDBsum:4R2R, PDBsum:4R2S, PDBsum:4WUU, PDBsum:5KL2, PDBsum:5KL3, PDBsum:5KL4, PDBsum:5KL5, PDBsum:5KL6, PDBsum:5KL7, PDBsum:6B0O, PDBsum:6B0P, PDBsum:6B0Q, PDBsum:6B0R, PDBsum:6BLW, PDBsum:6RSY, PDBsum:6WLH, AlphaFoldDB:P19544, BMRB:P19544, SMR:P19544, BioGRID:113327, IntAct:P19544, MINT:P19544, STRING:9606.ENSP00000331327, ChEMBL:CHEMBL4662942, iPTMnet:P19544, PhosphoSitePlus:P19544, BioMuta:WT1, DMDM:139778, jPOST:P19544, MassIVE:P19544, MaxQB:P19544, PaxDb:P19544, PeptideAtlas:P19544, PRIDE:P19544, ProteomicsDB:53673, ProteomicsDB:53674, ProteomicsDB:53675, ProteomicsDB:53676, ProteomicsDB:53677, ProteomicsDB:53678, ProteomicsDB:53679, ProteomicsDB:53680, ABCD:P19544, Antibodypedia:3523, DNASU:7490, Ensembl:ENST00000379079.8, Ensembl:ENSP00000368370.2, Ensembl:ENSG00000184937.16, Ensembl:ENST00000452863.10, Ensembl:ENSP00000415516.5, Ensembl:ENST00000530998.5, Ensembl:ENSP00000435307.1, Ensembl:ENST00000639563.3, Ensembl:ENSP00000492269.3, GeneID:7490, KEGG:hsa:7490, MANE-Select:ENST00000452863.10, UCSC:uc001mtl.3, CTD:7490, DisGeNET:7490, GeneCards:WT1, GeneReviews:WT1, HGNC:12796, HPA:ENSG00000184937, MalaCards:WT1, MIM:136680, MIM:156240, MIM:194070, MIM:194080, MIM:256370, MIM:607102, MIM:608978, neXtProt:NX_P19544, OpenTargets:ENSG00000184937, Orphanet:242, Orphanet:251510, Orphanet:220, Orphanet:83469, Orphanet:347, Orphanet:656, Orphanet:3097, Orphanet:654, Orphanet:893, PharmGKB:PA37395, VEuPathDB:HostDB:ENSG00000184937, eggNOG:KOG1721, GeneTree:ENSGT00940000156734, InParanoid:P19544, OMA:LDADPHC, OrthoDB:1318335at2759, PhylomeDB:P19544, PathwayCommons:P19544, Reactome:R-HSA-9690406, SignaLink:P19544, SIGNOR:P19544, BioGRID-ORCS:7490, ChiTaRS:WT1, EvolutionaryTrace:P19544, GeneWiki:WT1, GenomeRNAi:7490, Pharos:P19544, PRO:PR:P19544, Proteomes:UP000005640, RNAct:P19544, Bgee:ENSG00000184937, ExpressionAtlas:P19544, Genevisible:P19544, GO:0005737, GO:0005829, GO:0016607, GO:0005730, GO:0005654, GO:0005634, GO:0070742, GO:0001228, GO:0003700, GO:0000981, GO:0010385, GO:0044729, GO:0003723, GO:0000978, GO:0043565, GO:0000976, GO:0008270, GO:0035802, GO:0030325, GO:0001658, GO:0043010, GO:0060923, GO:0071320, GO:0071371, GO:0060539, GO:0030855, GO:0007281, GO:0032836, GO:0032835, GO:0008406, GO:0007507, GO:0001822, GO:0030539, GO:0008584, GO:0060231, GO:0072207, GO:0072075, GO:0072284, GO:0043066, GO:0030308, GO:0008285, GO:0045892, GO:2000195, GO:0072302, GO:0000122, GO:0017148, GO:0072112, GO:0043065, GO:1905643, GO:0045893, GO:0010628, GO:0060421, GO:2000020, GO:2001076, GO:1902895, GO:0045944, GO:0072166, GO:0003156, GO:0006355, GO:0006357, GO:0008380, GO:0007530, GO:0007356, GO:0009888, GO:0001657, GO:0001570, GO:0061032, InterPro:IPR017987, InterPro:IPR000976, InterPro:IPR036236, InterPro:IPR013087, PANTHER:PTHR23235:SF49, Pfam:PF02165, Pfam:PF00096, SMART:SM00355, SUPFAM:SSF57667, PROSITE:PS00028, PROSITE:PS50157
Sequence	mgsdvrdlnallpavpslgggggcalpvsgaaqwapvldfappgasaygslggpapppappppppppphsfikqepswggaepheeqclsaftvhfsgqftgtagacrygpfgppppsqassgqarmfpnapylpsclesqpairnqgystvtfdgtpsyghtpshhaaqfpnhsfkhedpmgqqgslgeqqysvpppvygchtptdsctgsqalllrtpyssdnlyqmtsqlecmtwnqmnlgatlkgvaagssssvkwtegqsnhstgyesdnhttpilcgaqyrihthgvfrgiqdvrrvpgvaptlvrsasetsekrpfmcaypgcnkryfklshlqmhsrkhtgekpyqcdfkdcerrfsrsdqlkrhqrrhtgvkpfqcktcqrkfsrsdhlkthtrthtgktsekpfscrwpscqkkfarsdelvrhhnmhqrnmtklqlal