|
|
| Record Information |
| Record ID |
190 |
| Pubmed ID |
30906300 |
| SNP |
DPB1?05:01 |
| Gene ID |
3115 |
| Protein ID |
P04440 |
| Vaccine Adverse Events |
antibody immune response |
| Vaccine |
inactivated Japanese encephalitis vaccine |
| Gene Name |
HLA-DPB1 |
| Official Symbol |
major histocompatibility complex, class II, DP beta 1 [Homo sapiens (human)] |
| Aliases |
DPB1, HLA-DP, HLA-DP1B, HLA-DPB |
| Other Designations |
HLA class II histocompatibility antigen, DP beta 1 chain; HLA class II histocompatibility antigen, DP(W4) beta chain; HLA-DP histocompatibility type, beta-1 subunit; MHC HLA DPB1; MHC class II HLA-DP-beta-1; MHC class II antigen DPB1 |
| Chromosome |
6 |
| Location |
6p21.32 |
| Annotation |
Chromosome 6 NC_000006.12 (33075990..33089696) |
| MIM |
142858 |
| DNA Sequence |
>NC_000006.12:33075990-33089696 Homo sapiens chromosome 6, GRCh38.p14 Primary Assembly
CCTTCTTTTCCTGACTGCAGCTCTTTTCATTTTGCCATCCTTTTCCAGCTCCATGATGGTTCTGCAGGTT
TCTGCGGCCCCCCGGACAGTGGCTCTGACGGCGTTACTGATGGTGCTGCTCACATCTGTGGTCCAGGGCA
GGGCCACTCCAGGTAAGAGCCGAACTGCCATTCTTGGAGGGTCTGGCTCAGGGAACAATTCCTAGGGGAC
GTTATCTTTAAGGGATCAAATTCTGAGACAGGCTGCGGGGGCTCCTGCCCTAAGGCAGTGTCCTCTCTTC
CCAGCTAGAGAAAGAGGTTCATCCCCTATAGGATAGCTTGCTACCCTACTGGCCTATTCTCTCTCCAAGG
ACATGGGTACAGTAAACAGAGAGAGGTGCCCAGTGGTCAGTGTCTTTGGGGAAAATGGGACCAAGAGGTC
CTGGATAACCTTGGACAGACAAGGTTTGCAGAGAGAGAAGTTGGCAAGTGCAGGCTCCTGGGCGTGTTCA
TGTCTGCATCCAGCCTGGAGGGGACTCAGGCAGAGAGCCCTAAGCTGGAGTGTCCAGGCTCTGAGGATCA
CTGAGGATTCAGTGCTCACGAAGAATGCCTCTTATTCCCCAGGGTGGAGCAGGAGCCCACATCCCTTGGA
CAATTAAGGAGAGAAGGGAGGGAGGGGGATAGGTTTTAGCCCCTGAAGGCATTCTCATTAAAGGTACTTC
TCCCAGCCTCCCCAGAACTTGGTTAGGGTACTAGAGTGGGTTGCGACTTGTAGGAAGAATGAGATGAGGT
TGTGTGGGTGCATGACAGGGATTGAGTGTAGGTTATCAGACAGCCAAGGAAGCAGTAACCAAGTGAAAAA
TCTCTTCTTCCTGCTGCCTCCCTGTGGCTGGTGTAATATTATGGCATCTATGATCCATTGTTTTTCTCTC
AGGATACTCTCAGGATATTTCTTTTTATATATATATATACTTTAAGTTCTAGGGTACATGTGCACAACGT
GCAGGTTTGTTACATATGTATACATGTGCCATGTTGGTGTGCTGCACCCATTAACTCGTCATTTACATTA
GGTATATTTCCTAATGCTATCCCTCCCCCCTCCCCCCACCCCACAACAGGCCCCGGTGTATGATGTTCCC
CTTCCTGTGTCCATGTGTTCTCATTGTTCAGTTCCCACCTATGAGTGAGAACATGTGGTCTTTGGTTTTT
TGTCCTTGCAATAGTTTGCTGTGAATGATGATTTCCAGCTTCCTCCATGTCCCTACAAAGGACATGAACT
CATCCTTTTTTATGGCTGCACAGTATTCCATGGTGTATATGTGTGCATTTTCTTAATCCAGTCTATCACT
GATGGACAGTTGGGTTGGTTCCAAGTCTTTGCTATTGTGAATAGTGCCGCAATAAACATATGTGTGCATG
TGTCTTTATAGCAGCATGATTTATAATCCTTTGGGTATATATCCAGTAATGGGATGGCTGGGTCAAATGG
TATTTCTAGTTCTAGATCTTTGAGGAATTGCCACACTGTCTTGAGATACCATCTCACACCAGTTAAAATG
GCGATCATTAAAAAGTCAGGAAACAACAGGTGCTGGAGAGGATGTGGAGAAATAGGAACACTTTTACTCT
GTTGGTGGGACTGTAAACTAGTTCAACCATTGTACTCTCAGGACATTTCTAGTCCAAATTTACACCAACA
CTCTGAGAGGAAGGACTGCAAAGTAGGTACCTTAGTTTTCCACTGACTTCCACTTTTCCTGCTTACACCC
TTCCTCCTAGACCTCTCCACACCCCTCCTAGGACACACCTAGAAGGTACTGACATCATGTCACCTCCTCA
TCTTTCAGGGTAGCAAGGTTGGAATCTCCTGAATACAGCCCCTCAAGCCCTAAAACCTCTTATCTATTAC
CTTGGGTTCATTGTCCAGGAAGGGGAGGAGAACTTGAACTTGTAGTCACAGAAGGGTGCTGAGAACTAAC
CAGCAGGACGGCTCAGCCCTGGGAACTGCAGAGGGGTGAGGCTGGGGAGAGAGGAGGCTGGAGCAGCACT
GGTGACACTGAACAGTGTCAGGAGGAAGTGACGGATGCAGCGCCCCCATCCCATAGGCAGAGCTGTCATG
TGGGATGAGGGACAGTGTTGGGAGCCACCAAGGAAACCCAGAGGTGGGGGAGCAGAGAGCAGAAGGGGGC
ATGTGATGCTGGGCAGTGAAAGGGAGGACGGGCAAAGGCTGGGTTGAGGTTTGTAGGGGGAATGAGATGA
GGCAGTGGAGCCATGTGACAGGGACTGAGGGTAGATTACTGGAGCTCCCTGCGTAGAATGAATGTTCAAT
CAAAACCTGCTGGAGGGAGAGCTGGAGCCATAGGGGAGTGGGTAAAGTGGGCAGGGCTGATTCCACAATT
CCCTGCATGCTCCCCCAACTCCACACACATCCCCAACCTCAAACAGGGCACAAGACCAAAGGGCTGAGGA
GCCAGGCTATAGCTTAAAGAGGCTGGGGGAGAAAAGCTTGGCTGAGACAACCCATAGGGAGCTAGAGGTT
TTTAATATATCCTATTCTGAATAAGAGACGAATTCATTCAGATCAGTGGTTTCAAACCGTGCTCTGGGCA
ACTCAATTGCTAAGGGTTCCACAAACAGGATAAAGTTTCTTATATACAAAAAAAAATGAAGGTTTCAAAT
TACACCATAAAACCCCTCATTGCTTATGTCTACTTGGCAGGTAAAATTCCATTTCAAAAGTTAAATGTAC
TTAAAAAATTACCTAAGACTGGGTAAATTAAAAAAATTAAATGTTGCAAAGAAAAAATTCAAAATTCTTA
TTCTTGAATGAAAAACGTTCTCTTACTGGTGATTGAGGAGGAGAAACAAAGACTAACAAATGAAAATGGG
AGAATCCACACTCAGAGTGGGGCAATTGAACAGGCAGGGGCGGATGGATGGCAGAGGAGGAGGAATCTGG
ACTCAAGGAGCTGGGGGGCTCTGGGCCTGGAATTTTAGGGTCTGGGGCCCAAGGCACCAGGAGAAGAGGC
AGGTCAGGATATCTGAGTCAAGACCTGGGATCTTGCCTTAGCAATGACACTGGAGACTAAAGGTGGACTC
CATGGTGCCCTTGAGCCCAGCCCTACCCCATCTCCACTATCCTCTGCCACCAGCTGTGCAACTTCTGCTA
GGGGTGAGGTTAATAAACTGGAGAAGTTAATTTGTGGAGCATGAAACAGATGAGCAGAACAATCACAGCA
CCTTAATTTCCCCAGTGTGCCCAAGAACAGAGCAGGCCTGAAGATACTCAAACAGAAACAAACATGTGCC
GTGTCACTGATAATTCTGTGTAGACACACACCTGCCAGACACTGCTCATGGCACTCCCTAGGAAGAACAG
CATGTGGGAAAGGCTGCCAAAATTGTTCATGTAAAAATTACATCAATGCTGTCTTCCTCGGTGCTGCCTA
TGCAGCTGGCAGCCATCTCTTCCTCCACATCATGGCCTCCCTCAGACTCCTCATGAAGGATAAGATCCTC
AAAAAGAGGACCAACAAGTTCATGAGGCACCAATCAGACTGAAATGTCAAAATTAAGCATAACTGGCGGA
AACCCAGAGGTCTTAACAGTAGGGTTCGTAGAAGGTCCAAGGGCCAGATCTTGATGCCCAACATTGCTTA
TGGGAGCAACAACAACAACAAAAAAAACATGCTGCCCAGTGGCTTCCAGAAGTTTCTGGTCCACAGCCTC
AAGGAGCTGAAAGTGCTGCTGATGTGCAACAAATCTTACTGTGCTGAGATCGCTCACAAAATTTCCTCCA
GAACTGCAAAGTCATCATGGAAAGAGTCACCCAGCCGGCCATCAGAGTCACCAACCCCAGTACCAGGGTG
CACAGCTAAGAAAATGAGTAGAAAGTTCATGTCCACGTTTTGTGTGTAAATAAAACCATAAAAACTGCCA
AAAAAAATTACATCAATGCCTCTAAACCCAAAGGACTCTACCCCCACAGGTCCCTGGTTGTTGTGGTGAT
TTTCATTGTGTAAAATACTTTCCACATCTTTTGACACCAAGTCTTTCTGCAGCCATGTTTGAAAATTAAC
TTTCAGGCTACAGAGTCTTTCTTATACCAAAGTTGAAGAAAGTTTTAAGAAATATATTTCTACATCTCCT
ACATGCAAAACAACAGGAGCAAGTTGAGGAATTCTCAAGAAACTGGTCGAGAAGAGAGAGCGCTTAGCTA
TGGAAAAGAGAAAGAAGGAAGGGAGGGCTTCCTGGAGGAGGTGGCATTTGAACCAGGACTGACATCAGGA
TGGAAATGTCAGTCAGGGAGTTAAGTAGGGGGAGCAGCTCCGCCCTCCACGTCCCCAGCTCCTCCCGCCC
CTGTTTTTTCTCCCAGTGACCCCACGTGAAACGTCTCCGCCTCCTCCAGCCACCAGCAGAAGGGACTGCC
TTCCCCTCAGTGCTCGCCCCTCCCTAGTGATCACTCAGTGCCCCTGAGCTCATTCTTTTCAGTAAATTCT
CTCTCTGCGTGGTGAGAAAACAGGCCTGGAGAGGCTCTGCGACCCGCTTAGGACCACAGAACTCGGTACT
AGGAAAACTCCTATTTTAAAATCCAGCCCTGGGTGGGAAGATTTGGGAAGAATCGTTAATATTGAGAGAG
AGAGGGAGAAAGAGGATTAGATGAGAGTGGCGCCTCCGCTCATGTCCGCCCCCTCCCCGCAGAGAATTAC
CTTTTCCAGGGACGGCAGGAATGCTACGCGTTTAATGGGACACAGCGCTTCCTGGAGAGATACATCTACA
ACCGGGAGGAGTTCGCGCGCTTCGACAGCGACGTGGGGGAGTTCCGGGCGGTGACGGAGCTGGGGCGGCC
TGCTGCGGAGTACTGGAACAGCCAGAAGGACATCCTGGAGGAGAAGCGGGCAGTGCCGGACAGGATGTGC
AGACACAACTACGAGCTGGGCGGGCCCATGACCCTGCAGCGCCGAGGTGAGTGAGGGCTTTGGGCCGGCG
GTCCCAGGGCAGCCCCGCGGGCCCGTGCCCAGGGCGCAGGAGCAGCCGGGTTGGCCTAAGGGACCTTAGT
GCCGGGCGGAAAGGGGACTTTGGGTTGGGGATTCATGGGGGGAGCCCATCTGGAGCTTGTCAGGGGAGCG
AGCGCGGGGACCTGGACTGGGCTGAGCATGGAGTGAGGAGGACGAGAGCAGAGAGACCCCCGGGACTTCA
TCAGGCCTGGCAGCTGACTGCATGTGGGGTGAAAAAAGGAAGCCACAGGACAGCGCACAAGGGTATGGTG
TGGAGATGGAGGTGGAGATGGCACAGCAGGCCACACAGAGAAGAAACCTACAGGGAGGTAGCTGGGTTTG
AGGTGCTTGAGGGGCAGATGGGTGGTCTGATGGGCAGGTAGACAGAAGGGTCTGCAGCCGGGGAGGAGAC
TGAGATACATGAGACCATCCAGGGAGAGGGGACCCAGGGGGAAGAGCAAAGGACCGGATCCTGGGAACTG
GACAGTTGTGATTTGGCCAAGACAGAAAAGCCTGTGAAAGAGACCAAAAAAACCCAAGTGCAGTGTGAGG
AGAGGCCCGCAGAGAAGAGTCTTGGAAGCTGAGGGGAGGTGACCTCAGCAGCACAGTGGACAGCGGTGCC
AGTGACTTGGGAAGGTCAGAAAACAGAAGATGGAAAGTGGGTTTGGAAACCAGGGAGACCTGGGGAGAGC
AGGTTGGCCGCAGCGGCAGGAGCTGGAATGGGAGGGGGTGCATGAGGCTGAGTGTGGCGCATCCTCCTCG
GGGCTGAGATGGATTTTACTTGTCTTGGGTTCCCCACGGCTGTCACAGGGCAGTGTCTCAGTTCATTCGT
CTTTTTCCTTCAGGAAGTCTGGGTGTAAAGGGATGGAGAGAGGTGAGGTGTGTGCAGTAAGAGGATTTCT
CAAGGATGGGACAGGAAGGCCTTGGAGCTTTGGCTTCCTCCTGTGAACTTGTGGGGTGGGGAGCCTGGTG
CACCAACCTGAGGGACTTGAGGGAGTAGTATCAGGATGTGGGATTGAGCCCTGGACCTTTTTTCTAGAAA
GAGGAAAAAAATGAAGGGAGGAGGAGGAGGAAGCTGGGGAGATCACACCTTTGATTTTCTTGTTCCTGGA
AAGTGAAAGGAAGTTCACCTGCTATGAGTGAGAAGGTGGACACACTGGGTGGGGATGAGGTGAGTGACAT
GAGCTTAGGAAAGTTGCTGAGGTAATTGGTTGAGAGAGGTGTTCAAATAAAAATAACGCAATTGGCAAAA
ACTGTTACTAAGACTTTGTAGAGGCACCAATCAGTGACATGGCAGCATTTTCTTTCACAGTAATCAACTG
CCAGATTGCAGACAGCCCTGATGCCAGCCTAAGGAGTGTGGGTTTCTCCTCCAGGCCCGCAGGTCCCCAA
CCTCACTCCTCTGAAGACTCTTCTGGAGATCCTCTGTGATGCACAGATCTCCAGACTCAGTGCCCCCAGA
CTCAGATTCCCTGGGTGGGGAGGTCTGGGGATCTCTGCTTGTAATCAGCTCCCTAGAGGTTCCCATGTAG
CCAGATAAGTATTGTCAGAACACTGAAGATTTTTGAAAAATGAAAAAGAGAAGGTTGGAGATGTGTCTTC
AGAAGACTACTAAGGGTGCTGGCTAGAGGAGGGACCAGAGGCAGGGAGATGAGGTAGGAAACTGCTATTA
TTTGTCAGGGAAATTGCAATCAAGGCATGAGTTAGAACAGGGAAAACACAGAGGCAAGGGAGAGGTGGAA
GGGGGAGGAAAGAAGTAGTGACAATTCCAGGGTGGATGTCCACCCAAATCTAGAAGTAATTGAGCAAATG
TTTTCTGGGCATTAGAGAAGGCAACTAGAACAAACAGGAATCCTTGCCTTGGTGAAATGTATTTGAACTG
GGTCAGAAATGAGGCCATTGGGTATCAGGCCTTAACTCCAGCGCACCCTGGAGGTCACTGATGTGGCTCC
AGGCTGACCTGCTCCTGTCAAAGAATATTGAGCAAGATGCCTCTCGTGGAATGTTCTGGGACCTTAAAAC
AGATACCCAAGTATTCCCCCTGATTTCATGGTTCCCAGAAGCTCTATGGGGAAGAAATTGTAGGTAATTC
ACAACTGAGATTTAGACATAAGTTGAATAGTGTAATGGACATTGAGTTAACCGAGGTAATGAAGTAGTGA
GACACAGGTGCCCCTGAAATAAACTCACATTGAGGGAAGAGGCTGACAATGTGGATCAGTCTGAAAACAA
GGCAAAAATACAATAGGGAGTAAGGGTTGTGTGTCAGTTCAAGACTGTACTTTTACCTGGCCCAGCGCCA
TGTTAGGGTATTTGTGTTCTCCAGGAAGTAGAAAGGAAAGAACTGAGTGATTAGGGACCTAGAAGACTAA
TTTGAGACATTCCTCTTGATGAGCTGTTCTCTAGGGTAGTCCTCTGAAAGAGCTGTTCTCTAGTGGATCT
CCCTGAATGAACTGTTCTCTAGGAGCACTTGACCCTTTTCTGTGTTTGTTTTTTGTTTTGTGTTTGTGTT
TGTTTTTGAGACAGGTTCTCACTTTGTCTCCCAGGCTGGAGTGCTGTGGCACCATCATGGCTCACTGCAG
CCTCAACCTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCATGTAGCTAGAACTACAGATACACGT
ACCACCATGTCTGGCTAATTTATTTTTCTTTTTAGAGATGGGTTCTCACTATGTTGCCCAGGCCGGTCTC
AAAACCCTGGGCTCAAGTGATCCTCATGCCTCAACCTCCCAAAGTGCTAAGATTATAGGCATGACCACCA
TGCCTGGCCTTTTCTGCTTTCTGAGGAGGAAAAAGGTACTGGTGGCAGAGATCCAAAAGAAAAGTTGCCA
GTGGCAGTGTGGAAATTCACCTGAGAACAACAGGACAAGCTGGGGCACAAATGCAAAGATGCAGAGGGAG
GCAACACCTGGTCATCTGTGAGACCTTCATGGGACCTGAAGACGCAGCACAGAGGAGGAACTTGAAAAAG
GACGGGATTTCTACTACTCAAGCATGTAGGAGCTCAGGATATTCTGTAAATATGAAGATTTTGAGTTTTT
GTAGGTGAGGTAAAAAAATACATAGGTTTTTTACAGAATAAGACATGTAAAGCTCTCTTCATTTTCTTTG
TATTTTCATGAAGTTATTAGATTCACAGGCCACCATAATGCCATTGTCTGTATATCTTAATTTCAAGATA
TTATTTGAGTAAATTTTGCTTCCTTTGTATCAAGATAGAACTTTGAAAAGGTAGGTAATTTCACAGTTGA
TCAAATATTCTTTGCCCAAATTACTTTTGGTTAAAATTTCTCCTAAATGTGCTACAGAGTGCAAACTCTG
TCTCCCTGCCATTCCGCTATATACTTACTAACTATTATTTTATTCAAGATCATGCATGCTCTACTTGAAG
GTCTATTTCTATCTTTTCAATGCTACCCTTACCCACTAGCCTAATCACATTATTCCTATTTTCAACATCT
AGGAATCAATTACATAGTGAACATGCCTAAGAAATAATAATCTGGGCAGATGCAGTGGCTCAGGCCCGTA
ATCCCAGCCCTTTGAGAGGCCGAGCGGGTGGATCACTTGAGGTCAGGCGTTGGTCAAGTGCTCCTAGAGA
ACCAGGCTGACCAACATGGAGAAACCTTGTCTCTACTAATAATACAAAAATTAGCCAGGTGAAGTGGCAG
GCACCTATAATCCCAGCTATTCGGGAGGCTGAGGAAGGAGAATTGGTTGAAGCCCGGAGGTGGAGGTTGC
AGTGAGCCAATATTGCGCCACTGCATTCCAGACTTGGCAACAGAGTGACACTCCATCTCAACAAAAAGAA
AGAATGAAAGAAAGAAAGAGCGAGATTATGTCTCAAAAAAAAGGAAGGAAGGAAGGAAGGAAGGAAGGAA
GGAAGGAAGGAAGGAAGGAAAGAAGGACAATCTCAAATTCTATTTCATTATTTTTCTTCCACGCTCCTAG
TCCAGCCTAGGGTGAATGTTTCCCCCTCCAAGAAGGGGCCCTTGCAGCACCACAACCTGCTTGTCTGCCA
CGTGACGGATTTCTACCCAGGCAGCATTCAAGTCCGATGGTTCCTGAATGGACAGGAGGAAACAGCTGGG
GTCGTGTCCACCAACCTGATCCGTAATGGAGACTGGACCTTCCAGATCCTGGTGATGCTGGAAATGACCC
CCCAGCAGGGAGATGTCTACACCTGCCAAGTGGAGCACACCAGCCTGGATAGTCCTGTCACCGTGGAGTG
GAGTGAGTCTCTGATGACCCTCTAGACCCCACCTCTGAAGAGCAGGGGACTCTCTGGCTCTGGGGTCCAC
TCATCTTATCTTCTGCATCTATACCCTGGGGCCATGTCCAAACCCCATCTTTCTTCTATACCAGCTCCTG
AGCATAGTTTGAAGCCAGGGAAATGGAGACTTCCTGACCTTGGCTTAGGGGTTCCTGAAGATTCATAGTT
CTCCCCCTTGTCAGAGAATCTAGGGACACTGACTGGTCTCGAAACCCTCACACTTAGGAACTGACCTCAC
ACATAGGAACAGTTCTCTTCCTTCAGCATTTTAGCCTCTTCTCAGGCATTTTGAGAGGCAACTTCCAGAA
TCAGCATTTGCCACCTTGTTGAGGTCACACCCCTGTTCCAGATATGAGGGTGGCTCTTTCTGAATTTCCT
CTTAGCAAGCTTTTTCCGCTGCACTGTCCTCATCCCGATATGCTGCATCAGGCTCCAGAATCTCAGACAG
GACATGAGTAGGGATGCAGCTGGTGGAGGTGACACTAAACCTGGGTCTGTCCTTCCCAGAGGCACAGTCT
GATTCTGCCCGGAGTAAGACATTGACGGGAGCTGGGGGCTTCGTGCTGGGGCTCATCATCTGTGGAGTGG
GCATCTTCATGCACAGGAGGAGCAAGAAAGGTGAGAAAGCCTGCAGGGTGAGCGGGACTTACCTTCCCCT
GGCATATTCACACTTATTCCACGATGAGGGGTTTGACAGAAAAGAAATGTCAGAAAGCTCTAGAGGCCAC
TGATATCAGATAATCGGGGAACAAACATGACCTATAGCGAGAGAGGGATCCCAGGCTGGGATCTTAATGC
AGCCAGATGCATGAGGTCCCAAGTACTCAGGCTCCTGCGGAGCGTCCATTGAGTGATGGGCAATGGAATT
TGGTGGGATGGAAATGTTTCTCTAATTATCTGAGGTGGTTTCAATGGCTGATTATATAACCTTTCGTCTT
TCATTTCAGTTCAACGAGGATCTGCATAAACAGGTAATATTCCTGCTTTGATTTCCTTGTGGGGTGGGTT
GCAGGAGGATATGAGTCCTTTCTGTGCATTGTAACACTGAGGCTCCTCCAGGAAGGGAATCTCAGGCATG
AACCCCTCTTTCAATGTCAGCCTTCAGGCAAGTGGGGAAAGAGCATTGCTTGGCTCCATTGCTGAAGGAA
GCAGAGATCAACTCTGTTATTTATCAGCCTGAGACGCATCCTCTCACCATAATTTTTCTCTCCTGGACTT
ACAGGAAGGAGGCTGGCAACCTGGGATAACTTGTCTTTTACCCCCACAGGGTTCCTGAGCTCACTGAAAA
GACTATTGTGCCTTAGGAAAAGCATTTGCTGTGTTTCGTTAGCATCTGGCTCCAGGACAGACCTTCAACT
TCCAAATTGGATACTGCTGCCAAGAAGTTGCTCTGAAGTCAGTTTCTATCATTCTGCTCTTTGATTCAAA
GCACTGTTTCTCTCACTGGGCCTCCAACCATGTTCCCTTCTTCTTAGCACCACAAATAATCAAAACCCAA
CATGACTGTTTGTTTTCCTTTAAAAATATGCACCAAATCATCTCTCATCACTTTTCTCTGAGGGTTTTAG
TAGACAGTAGGAGTTAATAAAGAAGTTCATTTTGGTTTAAACATAGGAAAGAAGAGAACCATGAAAATGG
GGATATGTTAACTATTGTATAATGGGGCCTGTTACACATGACACTCTTCTGAATTGACTGTATTTCAGTG
AGCTGCCCCCAAATCAAGTTTAGTGCCCTCATCCATTTATGTCTCAGACCACTATTCTTAACTATTCAAT
GGTGAGCAGACTGCAAATCTGCCTGATAGGACCCATATTCCCACAGCACTAATTCAACATATACCTTACT
GAGAGCATGTTTTATCATTACCATTAAGAAGTTAAATGAACATCAGAATTTAAAATCATAAATATAATCT
AATACACTTTAACCATTTTCTTTGTGTGCCATCACAAATACTCCTTAACCAAATACGGCTTGGACTTTTG
AATGCATCCAATAGACGTCATTTGTCGTCTAAGTCTGCATTCATCCACCAGCCTAGGCCTCCTGTCTTAA
TTTTCATACAGACAGAAATGACTCCCCACTGGGGAAAGAGCAAAGCAATACATGTAGCACTCTTTTTCAA
ACACTGGTCTTTTTTTTTTTCTTAACAATCCAACATTGTTATGTGTTTTGCGTCTCATATTGACACCTTT
TGGTCAAGGTAGAGGACATGTTTGTTGTAAGCTTTCTTTTTCGTGTAGAGGATGGATTCTTCACTCCTGA
TACACACAATCAGTGCACAGCAGCTCTCTTATACATCCAGTTGATGCCTTCAGTCTCCCTGGCTTCTTAC
AAGCATCTTCTGGGCCTTGTGTGTCCCTGGGCACCTGTCCCTGGTCAATTCCCGAAAGCTACTGTGCTCC
TCTTGCCCATCTCCCCTTGCAAATAATATCTTCCATCGGGGGACCGGCTTCCTCCAATTTCAGGAGAGGT
GGGGCTGAAGGCACAGACTTGGGCGTCACTGGCACAGATATAAGTAAATACAGCTGGAGTCTGCAGAGAG
GCTGGACTGAGTCAGGGAGTCAGGAAAGAGAAGCCACACACAAGGACAACCAATCATGTTTCTCATAATC
TTCTTAACCTAGGGAATAGGACACAATCATTTTTTCTTTTTAAAACATCTTTATCCCTGATCAGCCTCAT
TTCCTCAAAAACTATAAAGGAAAATGCTGCTGACTTGTTTTTGCGTAGTAATTTCAGCTGTCACATAATA
AGCTAAGGAAGACAGTATATAGTAAATAAGGACCCTTTATCTGTCTTATTTTCCCTTTTGGCTTCACAGG
AAACTTGTGAGAAACCTATGCAGCATAAAATTAATATGATTTCAATCCAGGGATTCAACGATGGAAGGAG
GTCATGAGAATAGCAGAAAGTCTTCAAATCGAGATCATTATGAAATCCTCAGACCCAGAGCACATAAATC
CTACCCTCAGAGTCACTGAGCAGTTAACATTACAAATTACAAACCATATCCAGTCAGAGTCATTCTCTTT
CCTGCTTGTCTCCTGTACTCATGTTACAGGTTAGGGCAGTACCCCGAGTGGAGTGAACAATCTCTGGACT
AACACTTGTCAGGATCAGAAGCTGAGGTATCTGCACCCACATTACAGGAACAGGATATGTGCTCCTAGGG
AACTGAGGGTGTCAGGAGATGAGGAATGTCCCTGGAGTCACAGAAAGAAGGTATCAGATGTGTCTCACTC
TGACATATGCAGGTGTTTATGAAACTCTGGGATTTCTAAGGAAGGATGCAGTGCAGAGACAGGTCCCAGA
GGAGACAAGAGCTGAGAGACCATCCAAACTGGGACCACCTTGTCACTAGACTTCAAATTTTCAATATTGA
TAGAGTGTTTTCTAAGAGTCAGGCCCTTTGCTGAGTGCTATGTGCAGCAGGATCAAAGGCAGCCAGGAGG
TAGAGGAGTCTTGAGGTACATCAGTCATTGGAGTTGAAGAGCAGAGATTCAAAGGAAAGTTGGAACTGGA
GCTTTAAAGGAGATGTGAAGTGGGTGACTCAACCTCTGACTCAGAAAAATTGATACCTGCAGAAGAAAAA
ACCCGGCGGGCTTAGGACTCCCAGCTGAGTGTTGTATCCTCCATCCCTTTCCACCTGGTCCCTTCATTTT
CTACCCCTCACAGTTCCCTAACGAGAAGGTGGTCCACCCAACAGACAACACTGCCTCAGATGGTTATCAA
GGGGTACCCTAAGAAGAAATCATCTCACCCTCTCTTTGTCCCCATTTGTCAAGTAGCAGTGAGGCCGAGC
CAGGGGATGGTGAAAGTGGAAGGAGGTGGGAGTTGGGCATCGGGTGTGAAGATGCTCTTGAAAGGGGTTT
TAATAACCACTTGCTACCAGGCCAGTGAACACTTACCATAGTTGATGCCTTTTGAGCATGTTGCATTGTA
AACTGTCCCTGAAATTACTGTGCACTTGGCTTATGGGATGAAACATCCTCCTAGTTCTTTTGTCTCTCAG
CTTCTCTGAAGTCTCATTGAGCACCTTCTCTTCAATTTCTTTTACACAGTAAGAATAGGATCAGCTGTGC
TAAACTAACAAATACCCAGATATCCAGGTTTGGCTCATGTTACACGTCCAAAGTAAGTCATGCAGGAAGC
TCTGCTCATCATCGTACTCAGGAAGTCAGGCTGACAGTCTTTCTCCTGCACATCTGCTCCCAGAACCTCC
CCAGCAGAATGAAGGGAACCTAAGAATTTATTCACTGGCTTTTAATGATCCCTCCTAGAAAGAACACACT
TCTCGCATTTCATTTTCCAATGTAAATCATATGGCTGCAACTAACTTCAAATAAGTGGGAATACTTGAAG
GTGGAAAACATTTAAGAAGTACACACTAAATAAATAATAAAATACTTCTACAAGAGA
|
| Protein Name |
DPB1_HUMAN |
| Length |
258 |
| Moltype |
AA |
| Topology |
linear |
| Division |
PRI |
| Update Date |
12-OCT-2022 |
| Create Date |
13-AUG-1987 |
| Definition |
RecName: Full=HLA class II histocompatibility antigen, DP beta 1 chain; AltName: Full=HLA class II histocompatibility antigen, DP(W4) beta chain; AltName: Full=MHC class II antigen DPB1; Flags: Precursor |
| Primary Accession |
P04440 |
| Accession Version |
P04440.1 |
| Other SeqIDs |
sp|P04440.1|DPB1_HUMAN,gi|122263 |
| Organism |
Homo sapiens |
| Taxonomy |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo |
| Comment |
On or before Mar 3, 2010 this sequence version replaced P01916.1, gi:74739463, gi:74722127, gi:74739571, gi:74739639, gi:74739722, gi:74739723, gi:74739724, gi:74739725, gi:74739726, gi:74739727, gi:74739728, P04232.1, P13763.1, gi:74739737, gi:74739752, gi:121945357, gi:121946664, gi:74739820, gi:121941045, gi:74739905, gi:74739907, gi:74739916, gi:74739922, gi:74739949, gi:74739950, gi:74739952, gi:74739953, gi:74739955, gi:74739980, gi:74739981, gi:74739989, gi:74739990, gi:74740000, gi:74740022, gi:121941541, gi:74740040, gi:74740056, gi:74740057, gi:74740058, gi:74740059, gi:74740075, gi:74740076, gi:74740077, gi:74740078, gi:74740079, gi:74740080, gi:74754565, gi:121944185, gi:121944232, gi:74755321, gi:74755322, gi:74755323, gi:74755324, gi:74755325, gi:74755327, gi:74755328, gi:74755329, gi:74755331, gi:74741581, gi:74741582, gi:74755529, gi:74755530, gi:74755975, gi:74756078, gi:74748135, gi:74748851, gi:74709691, gi:74709692, gi:74709693, gi:74748900, gi:74709694, gi:74748901, gi:74749272, gi:74749341, gi:74749763, gi:74749764, gi:74750002, gi:74750325, gi:74750606, gi:74750618, gi:74751336, gi:74751717, gi:74751718, gi:74752210, gi:74752503, gi:74752504, gi:74752507, gi:74752517, gi:74752854, gi:74753147, gi:74753213, gi:74753462, gi:74753463, gi:74760665, gi:70122.; [FUNCTION] Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molecule that presents an antigen, three MHC class II molecules (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molecules until primary high affinity antigenic peptides are bound. The MHC II molecule bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal microenvironment has been implicated in the regulation of antigen loading into MHC II molecules, increased acidification produces increased proteolysis and efficient peptide loading.; [SUBUNIT] Heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. In the endoplasmic reticulum (ER) it forms a heterononamer; 3 MHC class II molecules bind to a CD74 homotrimer (also known as invariant chain or HLA class II histocompatibility antigen gamma chain). In the endosomal/lysosomal system; CD74 undergoes sequential degradation by various proteases; leaving a small fragment termed CLIP on each MHC class II molecule. MHC class II molecule interacts with HLA_DM, and HLA_DO in B-cells, in order to release CLIP and facilitate the binding of antigenic peptides.; [INTERACTION] P04440; Q6FHY5: MEOX2; NbExp=3; IntAct=EBI-2802503, EBI-16439278; P04440; Q96CV9: OPTN; NbExp=3; IntAct=EBI-2802503, EBI-748974.; [SUBCELLULAR LOCATION] Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation.; [POLYMORPHISM] The following alleles of HLA-DPB1 are known: DPB1*01:01, DPB1*01:02, DPB1*02:01, DPB1*02:02, DPB1*02:03, DPB1*03:01, DPB1*03:02, DPB1*04:01, DPB1*04:02, DPB1*04:03, DPB1*05:01, DPB1*05:02, DPB1*06:01, DPB1*06:02, DPB1*08:01, DPB1*08:02, DPB1*09:01, DPB1*09:02, DPB1*10:01, DPB1*10:02, DPB1*11:01, DPB1*11:02, DPB1*13:01, DPB1*13:02, DPB1*14:01, DPB1*14:02, DPB1*15:01, DPB1*15:02, DPB1*16:01, DPB1*16:02, DPB1*17:01, DPB1*17:02, DPB1*18:01, DPB1*18:02, DPB1*19:01, DPB1*19:02, DPB1*20:01, DPB1*20:02, DPB1*21:01, DPB1*21:02, DPB1*22:01, DPB1*22:02, DPB1*23:01, DPB1*24:01, DPB1*24:02, DPB1*25:01, DPB1*25:02, DPB1*26:01, DPB1*26:02, DPB1*27:01, DPB1*28:01, DPB1*29:01, DPB1*30:01, DPB1*31:01, DPB1*32:01, DPB1*33:01, DPB1*34:01, DPB1*35:01, DPB1*36:01, DPB1*37:01, DPB1*38:01, DPB1*39:01, DPB1*40:01, DPB1*41:01, DPB1*44:01, DPB1*45:01, DPB1*46:01, DPB1*47:01, DPB1*48:01, DPB1*49:01, DPB1*50:01, DPB1*51:01, DPB1*52:01, DPB1*53:01, DPB1*54:01, DPB1*55:01, DPB1*56:01, DPB1*57:01, DPB1*58:01, DPB1*59:01, DPB1*60:01, DPB1*62:01, DPB1*63:01, DPB1*65:01, DPB1*66:01, DPB1*67:01, DPB1*68:01, DPB1*69:01, DPB1*70:01, DPB1*71:01, DPB1*72:01, DPB1*73:01, DPB1*74:01, DPB1*75:01, DPB1*76:01, DPB1*77:01, DPB1*78:01, DPB1*79:01, DPB1*80:01, DPB1*81:01, DPB1*82:01, DPB1*83:01, DPB1*84:01, DPB1*85:01, DPB1*86:01, DPB1*87:01, DPB1*88:01, DPB1*89:01, DPB1*90:01, DPB1*91:01, DPB1*92:01, DPB1*93:01, DPB1*94:01, DPB1*95:01, DPB1*96:01, DPB1*97:01, DPB1*98:01 and DPB1*99:01. The sequence shown is that of DPB1*04:01.; [SIMILARITY] Belongs to the MHC class II family. {ECO:0000305}.; [SEQUENCE CAUTION] Sequence=AAQ12564.1; Type=Frameshift; Evidence={ECO:0000305}. |
| Source Db |
UniProtKB: locus DPB1_HUMAN, accession P04440;; class: standard.; extra accessions:A0PFJ7,A5I886,A8YPB3,B5U8B4,B7VF80,B7VF87,B8ZX68,B8ZYT0,B9W5S8,B9W6F7,B9W6F9,C0MPP5,C0MPQ2,C0MPQ3,C0MPQ5,C0MPQ6,C0MPQ7,C4R9J5,C5IZL1,O00259,O19698,O19700,O19702,O19749,O46884,O77952,O98215,O98216,O98217,O98218,O98219,O98222,O98223,P01916,P04232,P13763,P79493,P79608,Q0P0L4,Q0ZFN3,Q14279,Q27S71,Q29682,Q29684,Q29698,Q29714,Q29775,Q29776,Q29778,Q29779,Q29781,Q29827,Q29828,Q29879,Q29880,Q29898,Q29977,Q2MGW3,Q30015,Q30031,Q30032,Q30033,Q30034,Q30050,Q30051,Q30052,Q30053,Q30054,Q30055,Q30174,Q4GY31,Q4JHD8,Q5ENE0,Q5ENE1,Q5ENW3,Q5EP46,Q5EP47,Q5EP49,Q5EP51,Q5EP52,Q5EP53,Q5EP56,Q5I4H8,Q5I4H9,Q5ISH4,Q5ISH5,Q5SQ73,Q5STP2,Q5YLA6,Q6IVX1,Q6LBX2,Q6LBX3,Q6LBX4,Q6LBX5,Q6LBX6,Q6LBX7,Q6PWX6,Q6TAS4,Q714U1,Q714U2,Q7YQ10,Q860Z7,Q8HWL7,Q8HWT5,Q8SNC4,Q95HC1,Q95IT7,Q95IT8,Q9BD13,Q9GIM2,Q9GIM4,Q9GIX6,Q9GJ41,Q9MY67,Q9TNT7,Q9TQE2,Q9XS11,Q9XS12; created: Aug 13, 1987.; sequence updated: Aug 13, 1987.; annotation updated: Oct 12, 2022.; xrefs: X01426.1, CAA25672.1, X02964.1, X03023.1, CAE82008.1, X03024.1, CAE82007.1, X03022.1, CAA26823.1, X03025.1, CAE82037.1, X03026.1, CAE82042.1, X03028.1, CAE82073.1, X03027.1, CAE82043.1, X03067.1, CAA26871.1, X02228.1, CAA26147.1, J03041.1, AAA35993.1, M83664.1, AAA59837.1, AY804132.1, AAW78737.1, AY804133.1, AAW78738.1, AY804135.1, AAW78740.1, AY804136.1, AAW78741.1, AY804137.1, AAW78742.1, AY804138.1, AAW78743.1, AY804139.1, AAW78744.1, AY804141.1, AAW78746.1, AY804142.1, AAW78747.1, AY804143.1, AAW78748.1, AY831401.1, AAW80919.1, AY831402.1, AAW80920.1, AY831403.1, AAW80921.1, AY831404.1, AAW80922.1, AY656678.1, AAV71025.1, AY656679.1, AAV71026.1, AY656680.1, AAV71027.1, AK313305.1, BAG36110.1, BT019780.1, AAV38583.1, AL645931.7, AL662824.9, AL805913.4, AL845446.7, BX120009.10, CR759795.4, CR759904.5, CR762479.5, CH471081.1, EAX03674.1, BC007963.2, AAH07963.1, BC013184.1, AAH13184.1, M28202.1, AAA53197.1, Y09327.1, CAA70507.1, L31816.1, M97686.1, X96985.1, Y13900.1, CAA74199.1, Y14230.1, CAA74608.1, Y16095.1, CAA76060.1, AY823995.1, AAW79272.1, AJ563603.1, CAD91639.1, AM039828.1, CAJ01690.1, AM408787.1, CAL64063.1, AM698036.1, CAM91695.1, M84619.1, M84620.1, M84622.1, M84623.1, M84624.1, M84626.1, X82123.1, CAA57635.1, U22311.1, AAB60413.1, U22313.1, AAB17108.1, K01615.1, AAA36313.1, FM883600.2, CAT04585.2, FM882212.1, CAT03206.1, FM956650.1, CAX11690.1, FM991729.1, CAX20314.1, FM992080.2, CAX21583.2, FM992366.1, CAX30407.1, FM992364.1, CAX30405.1, FN252853.1, CAX53275.1, FN256250.1, CAX53717.1, FN256251.1, CAX53721.1, FN256254.1, CAX53718.1, FN256253.1, CAX53726.1, FN256255.1, CAX53722.1, FN393829.1, CAY85528.1, M23675.1, AAA59740.1, M62326.1, AAA59719.1, M62331.1, AAA59724.1, L07768.1, AAA59690.1, D13174.1, BAA02465.1, D10834.1, BAA01614.1, D28809.1, BAA05970.1, X96986.1, CAA65710.2, X91886.1, Y18498.1, CAC12860.1, AJ238005.1, CAC12865.1, AJ271373.2, CAB70605.2, AF288354.1, AAG30143.1, AJ292074.1, CAC27995.1, AF536241.1, AAN33050.1, AF549409.1, AAQ12563.1, AF549410.1, AAQ12564.1, AJ514871.1, CAD55852.1, AY374100.1, AAR21105.1, DQ206450.1, ABB17974.1, M83914.1, AAA36264.1, M83915.1, AAA36259.1, M83916.1, AAA36260.1, M83917.1, AAA36261.1, M83918.1, AAA36262.1, M83919.1, AAA36263.1, AJ297820.1, CAC14048.1, AY029777.1, AAK40344.1, AF489518.1, AAL92172.1, AF492640.1, AAO84765.1, AY425707.1, AAR29060.1, AY572830.1, AAS77869.1, AY855160.1, AAW33682.1, AY855161.1, AAW33683.1, DQ089022.1, AAY98352.1, AB247517.1, BAE78492.1, DQ386161.1, ABD36812.1, DQ485789.1, ABF47047.1, AM887530.1, CAP08783.1, FM211032.1, CAR66500.1, FJ976693.1, ACS12738.1, L17310.1, AAA53479.1, L17311.1, AAA53480.1, L17313.1, AAA53481.1, L17314.1, AAA53482.1, L22076.1, AAA53476.1, L22077.1, AAA53477.1, L23400.1, AAA58441.1, U59437.1, AAD09481.1, U59438.1, AAD09482.1, U59439.1, AAD09483.1, U59440.1, AAD09484.1, U59441.1, AAD09485.1, U59442.1, AAD09486.1, AF074845.1, AAD39682.1, AF074846.1, AAD39683.1, AY033075.1, AAK51161.1, U34033.1, AAA81335.1, Z92523.1, CAB06822.1, X78042.1, U29534.1, AAB52511.1, AY618897.1, AAT40308.1, X97406.1, CAA66059.1, L01466.1, M87046.1, D10478.1, BAA01281.1, D10882.1, BAA01704.1, U94839.1, AAC64232.1, X80752.1, CAA56728.1, AF077015.1, AAC26835.1, K00409.1, AAA36312.1, HLHUS1, HLHUPB, D30536, D30537, E30536, I37298, S49382, HLHUS2, I38197, I59621, I59637, I59641, I81234, I81235, I81236, I81237, I81238, NP_002112.3, 3LQZ_B, 4P4K_B, 4P4K_F, 4P4R_B, 4P4R_D, 4P57_B, 4P57_D, 4P5K_B, 4P5K_E, 4P5M_B, 4P5M_D, 4P5M_F, 4P5M_H; xrefs (non-sequence databases): CCDS:CCDS4765.1, PDBsum:3LQZ, PDBsum:4P4K, PDBsum:4P4R, PDBsum:4P57, PDBsum:4P5K, PDBsum:4P5M, AlphaFoldDB:P04440, SMR:P04440, BioGRID:109360, IntAct:P04440, MINT:P04440, STRING:9606.ENSP00000408146, GlyConnect:1366, GlyGen:P04440, iPTMnet:P04440, PhosphoSitePlus:P04440, SwissPalm:P04440, BioMuta:HLA-DPB1, DMDM:122263, jPOST:P04440, MassIVE:P04440, MaxQB:P04440, PaxDb:P04440, PeptideAtlas:P04440, PRIDE:P04440, ProteomicsDB:51715, Antibodypedia:28872, CPTC:P04440, DNASU:3115, Ensembl:ENST00000399500.6, Ensembl:ENSP00000382422.2, Ensembl:ENSG00000215048.13, Ensembl:ENST00000411749.6, Ensembl:ENSP00000414196.2, Ensembl:ENSG00000236693.11, Ensembl:ENST00000418931.7, Ensembl:ENSP00000408146.2, Ensembl:ENSG00000223865.11, Ensembl:ENST00000425130.6, Ensembl:ENSP00000396095.2, Ensembl:ENSG00000230763.11, Ensembl:ENST00000433800.6, Ensembl:ENSP00000407674.2, Ensembl:ENSG00000226826.10, Ensembl:ENST00000454006.6, Ensembl:ENSP00000389288.2, Ensembl:ENSG00000237710.10, GeneID:3115, KEGG:hsa:3115, MANE-Select:ENST00000418931.7, UCSC:uc003ocu.3, CTD:3115, DisGeNET:3115, GeneCards:HLA-DPB1, HGNC:4940, HPA:ENSG00000223865, MalaCards:HLA-DPB1, MIM:142858, neXtProt:NX_P04440, OpenTargets:ENSG00000223865, Orphanet:133, Orphanet:900, PharmGKB:PA35064, VEuPathDB:HostDB:ENSG00000223865, eggNOG:ENOG502RYNI, GeneTree:ENSGT00940000162390, InParanoid:P04440, OMA:ICQVEHT, OrthoDB:1249505at2759, PhylomeDB:P04440, TreeFam:TF336626, PathwayCommons:P04440, Reactome:R-HSA-202424, Reactome:R-HSA-202427, Reactome:R-HSA-202430, Reactome:R-HSA-202433, Reactome:R-HSA-2132295, Reactome:R-HSA-389948, Reactome:R-HSA-877300, SignaLink:P04440, SIGNOR:P04440, BioGRID-ORCS:3115, ChiTaRS:HLA-DPB1, EvolutionaryTrace:P04440, GeneWiki:HLA-DPB1, GenomeRNAi:3115, Pharos:P04440, PRO:PR:P04440, Proteomes:UP000005640, RNAct:P04440, Bgee:ENSG00000223865, ExpressionAtlas:P04440, Genevisible:P04440, GO:0009986, GO:0030669, GO:0030666, GO:0010008, GO:0012507, GO:0000139, GO:0071556, GO:0005765, GO:0016020, GO:0042613, GO:0005886, GO:0032588, GO:0030658, GO:0023026, GO:0042605, GO:0002250, GO:0019886, GO:0002503, GO:0032729, GO:0050870, GO:0042102, GO:0050852, Gene3D:2.60.40.10, Gene3D:3.10.320.10, InterPro:IPR007110, InterPro:IPR036179, InterPro:IPR013783, InterPro:IPR003006, InterPro:IPR003597, InterPro:IPR011162, InterPro:IPR014745, InterPro:IPR000353, Pfam:PF07654, Pfam:PF00969, SMART:SM00407, SMART:SM00921, SUPFAM:SSF48726, SUPFAM:SSF54452, PROSITE:PS50835, PROSITE:PS00290 |
| Sequence |
mmvlqvsaaprtvaltallmvlltsvvqgratpenylfqgrqecyafngtqrfleryiynreefarfdsdvgefravtelgrpaaeywnsqkdileekravpdrmcrhnyelggpmtlqrrvqprvnvspskkgplqhhnllvchvtdfypgsiqvrwflngqeetagvvstnlirngdwtfqilvmlemtpqqgdvytcqvehtsldspvtvewkaqsdsarsktltgaggfvlgliicgvgifmhrrskkvqrgsa |
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