|
|
| Record Information |
| Record ID |
138 |
| Pubmed ID |
34526360 |
| SNP |
|
| Gene ID |
2150 |
| Protein ID |
P55085 |
| Vaccine Adverse Events |
transient lymphopenia, injection site reaction, fatigue, flu-like symptoms temporally related to vaccination, and arthralgia and decreased lymphocyte count, asymptomatic transient elevations in autoimmune serologies |
| Vaccine |
IGFBP-3 N-terminus plasmid-based vaccine |
| Gene Name |
F2RL1 |
| Official Symbol |
F2R like trypsin receptor 1 [Homo sapiens (human)] |
| Aliases |
GPR11, PAR2 |
| Other Designations |
proteinase-activated receptor 2; G-protein coupled receptor 11; coagulation factor II (thrombin) receptor-like 1; protease-activated receptor 2; thrombin receptor-like 1 |
| Chromosome |
5 |
| Location |
5q13.3 |
| Annotation |
Chromosome 5 NC_000005.10 (76819030..76835315) |
| MIM |
600933 |
| DNA Sequence |
>NC_000005.10:76819030-76835315 Homo sapiens chromosome 5, GRCh38.p14 Primary Assembly
GAAACCTAACCCGCCCTGGGGAGGCGCGCAGCAGAGGCTCCGATTCGGGGCAGGTGAGAGGCTGACTTTC
TCTCGGTGCGTCCAGTGGAGCTCTGAGTTTCGAATCGGCGGCGGCGGATTCCCCGCGCGCCCGGCGTCGG
GGCTTCCAGGAGGATGCGGAGCCCCAGCGCGGCGTGGCTGCTGGGGGCCGCCATCCTGCTAGCAGCCTCT
CTCTCCTGCAGTGGCACCATCCAAGGTGAGAAACCTGGCCAAGGAGGGCTCTTATCTCTGAGGAGCTGGG
GTCCTGGGCACGCTGGGCAGACGGTGGGATCCGGGCAGGTGTGCGAAGGCTGTTCTGCTGCCGGCACCCA
TCTCTACGAATCCCTTAGCCTCCCCTTGGTGGCTTTGATGTGAGGTCTCTGCGCCAAGGAGGCACCCAGG
TGGGACATGCGGGAGCAGCTGAAGTCAGCGGAGCCGGGCAGAGGCAGAGATTTCCCCAAAGACCCCACTT
CCCGTAGAGGCTGTCATGCTGGGCACCTCCAGGCCCCAGCGTGGGTTCGGGGAAAGGGAGGGAAGGAAGG
AGTAGCTGTGTCTAAAGGGTACGCAGAGGACCTAGTCCCCTCCCCGGGCTTGGTTGCTTTGTAAACACTA
AGTCATTAAGAGCTTTTTGCCAACTCCGGAGACTTCCTCCGCTGGCCCCGCGGGGCCGGTGGGGTTAGCG
AGCTGATTGCGCAGGGCAGGGCGGAGTGGGTGGGAACCCGCGGCCCGGGAGCCTTCTAGGTTGTTTTTTG
CGTCCCTCTCCAACTGCTGGAAGCCTTTCTTCGGGTTCTGGCCCCTGCGTTCGAGACCCACCCGGGTCCC
GCTGCTCCTGGCACCCACAGTGGAAGGCCCGGGGTATGAAAGTCAGGGCCGGTCCCTGATGGGTTCTGGT
GGTAATGAGCGCTCAGGCCCGTTGGGCGCCACGAGGATTTACGAGCGGAACTTTTTGGACCCTGCCTTAT
ATTTGACCAGTTGACCCTCTGGGCCTGGGGTTCCGGGACTTTCCTAGTGTGCCACCCGGAGCGGCCACTG
GCTGCCACCCAGGTCTGCAGGCCAGAGGCTGGCTGGCCTGGGAACAGAGCAGCACTTGCGCCCGGCCGTC
GCGTTCCTTGGATGTGCTGCTCCGGGTGTGCTCGAACTTGTATTGCTGGGAGTGTGTTCTTCCGGGCCCA
GCAGGCCTCGCTGTGGCCGTGGGGGATGTTTGACCTGCGATCGCGCCACTGTGATCCTAACCGAGGCCCC
TCTGTTTGGGGCAGCCTGGGTAGCAAAGGGAGCTTTTAATTTCCCTCAGAAATGCGCATTTCTCACTTTT
ATCCTCCTCTTCATAAAGACGAAGTAAAAGAGCAAGTCACAGTGGGTTGGAATTAGATGGAAGAATGTGA
TTCTTTTCCCTCTGCAGTTAGGGAAAAGGGTGTTAATGGTGTAAGCTTGAAAACTGTGCACCGCTGGTAT
ATTTTTTTTTCTTAATCAGCATCAGAATAAAGGCATTTAGTTCCAGGAAGTATTGAAAACTGTAATGGAC
ACCTCTCCTCTATGTCCTTTAAAGTTGGAAACTTAAAATTCAGGAGCAAAGGTTAGTATGTGCAAACTTT
AAAAAAATACATGTTGGTATAGCTGATTCAACATCTTTATGATTCAGAGATCCCTGTAGGAAGCATGCCC
CGATTATTTGTCTTGTTCTTGTTTACTACTCTTGGGGGATTGGGAGATCCCTGGATTATAAGGCGAACTT
GATTTAACAATAAGGAAAAATCAGGTTACTTGTTAACTATAGCCACTTAATATTGCACCTTGTTCCTCAT
CCTCCCCCCACCATACTTTTATTCCCTTGCAAAGTAACTTTCCCAAAGGGTTAGTGAAGTAACACTGACA
ATTGATTTAGGCAGATGGAGCTTTCCTCCCACCTTAAAACTAAATTGATTTTAATAAGAAATACAGTGTT
AGCAAAGCTTTTCTGCCCTCAGGGTGGGTCTTTGCTCACTCGCTTTTTAGCCGGTCCTTCTGCGTGCCCC
TCAGGTGGCTGCAGGGCCGATTTGGGGTTTGATTTTCTTCCCAAAGCCTCACTCCAAAAGACTGCCTCAT
AGAAACGAACTCAGCCGAGATCACAACCTTCTCAGGGTACAGGTGAAGGACACTGAATTGAGGAGGCAAG
GCAAGGAAAACACTTGGAAATCAGGGCTTCTCTTTCCCTTTACAATAGTAATTGATAATTATTTGGGTAA
ACATGCTTAATATGTGTCCTCACTGCATCGTTAACTCCTGGAGGCAGGGGGCCCTACCATCCTTTCCATC
ACGTCTAGCATAGTCTCATCACCTACGGGACCTCAGTAAATAGCAAATGAATGAAGTGAGGAGTCTTGCC
CAGAGTACCCTGGCTGGTCCATGTGGTGTTCATTTCAGTCAGCTTCTCTCTGCCACTTACTTATTTTTTT
CCACCATGTTACAGGCCTAGGTCATTCCATTTATCTTTTGGAGACTGGAACTTCTGTTTTCTTTATAATT
GGTTTGGTGGTTTTTTTTTGTTTTTTTGGTTTTTTGGGTTTTTTTTTTTTTTGACTCTCATTCGGTTGCC
CAGGCTTGAGTGCAGTGGTGCAATTTTGGCTCATTGCAACCTCCACCTCTCCCGGGCTCAAGGAAGTCTC
CTGCTGCAGCCTCCCGAGTAGCTGGGACGACAGGCACGCACCACCACCCCCAGCTAATTTTTGTATTTTT
AGTAGAGACAGGGTTTCACCATATTGGTCAGGCTGATCTCAAACTCCTGACCTCAGGTGATCCACCCACC
TTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCTACTGCGCCCTACCTATAATTGTTTTTTAAATT
ATAAAAACAATATGTGATCACTCGAGGGAAAAATGAGCCAAAACAAAAAAAGGAAACATTTAATTAAATC
ACCCTGAACTTCAGTACCAAAGTAGCCACCGCTAATATTTCGGCTTATATATTTTCCCACTCTTTATTAC
ATCCATGCACAAAATATGTATTCACAAATACAGAAAATATGTTTGTGCAAGTATGGGATTATATAAGCAC
ATCAGTATCATGTCAATACATATAAAACATTTTTAATGACTCCAAAATGTTACAGAAGGATGCATCAATT
TTAAAATTAGTCCTTTGTTGATAGACATGTGGTATTTCCATTTTTTTTTTCCCCCTGAGATAGAATCTCA
CTCTGTTGCCCAGGCTGTAGTGCAGTGGCACGATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTTAAG
TGATTCTCATGCCTCAGCCTCTGGAGTAGCTGGGACTACAGGCGCACACCACCACATCCAACTAATTTTT
GTGTTTTTGGTATAAACGGGGTTTCGCCACGTTGGCCAGGCTGATCTTGAACTCCTGACCTCAAGTGATC
CACCTGCCTCAGCCTCCCAAAGTGCTGGGATTATAGGCATGAGCCACCGTGCCTGGCCAAAGTTTTGTAA
TATGACAGAACACTGCAATGAACTGGAAGATAGGACTTTAAATTTGATCCTTTTGCTTGCTTTGTAGTTA
CTAAATAACCTTGATAGATGATGTTTTAGTAAATCTGTATTTGACTTTCTTATGGTTTTATTAGCTTGGC
AAGTGTTGAAGAAAACAGTTCATTCTGAAAGAACACTTCTGAAAATGTACTAAAAGTTTAGCTAGGGAGG
GGCACCCCACAATTGAAACCTTTATTTTTCAGTCTGTGCTCCCAAAGATTGGGAGCAAAAAAGGACATTT
GGGGTGAGGGGATCATAGAGAAGAGAGGGTGAAAGGAAGAGAACTAATGCAAGTAAAGTGCTTGTTTTAC
ACTTGGTTTGATGGGGAGGTTGGGCCACAAGAGGAGTATACTTAAAATAAAAATTAAATTAAAAGTTTTA
GGCCAAGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGAAGTCAAGGCGGGTGGATCACAAGGTCA
GGAGATCAAGACCATCCTGGCTAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATTAGCCGGG
CATGGTGGCGGGCGCCTGTAGTCCCAGCTGCTTGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAG
GTCGAGCTTGCAGTGAGCCGAGATCGTGCCTCTGCACTCCAGCCGGGGCAACAGAGTGAGACTCAGTCTC
AAAAAAAAAAAAAAGTTTTACACGCAGATTTTCCCAAAATTGTGTAAATCAGAAGGGTCTAAAAAAAAGT
GAAAATCTCTCATTCTTTCTGGTCTCCAATCTCAGCACAACTTCTCGGGTTTTGTTTGTTTGGTTGGTTG
GTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTGTGTCGCCCAGGCTGGAGGGCTGGAGTGCAGTGAT
GTGATCTCAGCTCACTGCAACCTGCGCTTTCCAGGTTGAAGTGATTCTCCTGCCTCAGCCTCTCAAGTAG
ATGGGATTACAGATGCGCGCCAACACCTCCAGCTAATTTTTGCATTTTTAGTAAAGCCAGAATTTTGCCA
TGTTGGCCAGGCTGGTCTTGAATTCCTGACCTCAAGTGATCCGCCCGCCTTGGCCTCCCAAAGTGCTGGG
ATTATAGGTGTGAGTCACTATTCCTGGCCATCAGCTCAACTTCTCTATGCACAAATGATTTATAGGAATA
GAAGGAGCATACCGTACTGTACATACTGTGCTATGATTTATTTATCTTTTTTACCTAATCGATTCATAGT
CAGTTTATAGAAATCTGTACAAACTTTTTTTTTTTTTTTTTGAGACGGAGTCTTGCCGTGTCGCCCAGGC
TGGAGTGAAGGGGCGCTATCTCAGCTCGCTGTAAGCTCTGCCTCCCGGGTTCATGCCATTCTCCTGCCAC
AGCCTCCCAAGCAGCTGGGACTACAGACGCCCGCCACCATGCCCGGCTAATTTTTTGTATTTTTAGTAGA
GACAGGGTTTAACCGTGTTAGCCAGGATGGTCTCGGTCTCCTGACCTCGTGACCCACCTGCCTCGGCCTC
CCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCGACCCTGTACAAACTTTTATAGGGGGGTAATTG
AACTAGTCCTCCCCACCACACCCCCCCCCCCTTTTTTTTTTAAAGAGACTGGGTCTGGCTGTCACCCAAG
CTGGAGTGCAGTGGCAGGATCATAGCTCACCCCCAGCTAATTTTTTTTTTAGACGGAGCTCCCAAGTAGC
TGGGGCTATGGCTAGGTTGCCACTATGCCTGGCCTGAACTACTCCCCTCTTCCCGCCCATCCCCGAACCC
CAGATGAAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCCGC
CTCCCAGGTTCAAGCCTCCCAGGTTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCCCGCCACCACACCC
AGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCACGCTGATCTCAAACTCCCGAT
CTCATGATCCGCCCGCCTTAGCCTCCCAAAGTGCTGGGTTTACAGGCGTGAGCCACCCTGCCAGGGCCTG
AACTACTCCCCTTTTTGATAGATGTTGAAATTAACATTGTTTTACCATGCTAAACAATGTTCCAGTGAAT
ATTCTAGTACATAAAATAGCTTTGTGCACTTTAGCTGGTAGGTGCAGGGCAAATTCCTAGAAGTAAATTG
CTAGGTCATATGGCAAATACATTTAAAATTTTGATATGTTTTGCCAAATTACCCACCAAAAATATTATAT
CAATTTATATTCCTTTGAGATACAAAATTCAAATAATATAGAGAGGTGTAAAATAAAAAGAAAAGTTCTC
TTGTCCCCAGCTATTCTACTCCACAGAGCCAGCCACTTTTTATTGTTTGGTGGATATCCTTCTAGACTTC
AGATTTTGCAAATTGTACATTATAATTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTTGCC
AGGCTGAAGTGCAGTGGCATGATCTCGGCTCACTGCAACCTCTGCCTTCTGGGTTCAAGCGATTCTCCTG
CCTCAGCCTCTGGAGTAGCTGGGACTACAGGCGCGTGCACTACACTTAGCTAATTTTTGTATTTTTTAGT
AGAGATTGGGTTTCACCATGTTGGTCAGGATGGTCTCGATCTCTTGATCTCAGGATCCACCCGCCTCGGC
CTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCTGGCCAGTTTCTTTTTTCAATTGACTGTAT
ATTGTGGCTGTCTTTCCATTTCAATATTATTGGCTACTATATTGTCTACCCTTAGTAGTAGGGACTACGT
CAGGGACATGCTAAGTTAGGAATAGAAATAAGGAGCTGTTTGTCTGTAACTGAGTGGGGGGATGCTGCCT
TGAGCATCTGTGAGTGTGTATTTTCACACACTTGGGCAATAATTGTTTATTACAGCCCTAGAAATGGGAA
TGTAATTGTAGCCAGGCACTTTATTTGTGTTTAAACTTCATTTGTGCATTTAGTCTCTCCTCAACTCTGT
GAAATAGAAATGATTTTACCTGGTTGACAATTGGGAGCTGGGATAGCATCGGTTCTCTAGACAAGCTCTG
TGAGTTTTGGTGAGTGGTAAGGACCCTGTACAGAGTCAGAGCAAATGCACTGGGCAAGGGCTTCAGGGAC
CTTCGAGTAGCATCTTGACATTTACCAGTGTTATAGAACAGTTAATATCAACAATAGTTTTGATGGAGAC
CATTAAAGGTTATGTGTTGAAATATTCTAAGAAAAAGTTCCTTTTTAAAAAAAAATTGTTATATTGCCAT
TCCTTGCTCCTTTTTTGGTCTTTATTTTAGCATTCTTATTTAAAACAGATTTTGAGCACTCTTTATGTGA
GCTTTCCTGACTTGGTACATGCTTATTTTTATGGAGAATTTTAATCTTATAGAAATATACTATTATAGTG
AATTAAGTGTATCCACCACTCAACTTCAATAATTATTAACTGTTGGCTAATCTTGTTTCATCTATTCCCA
AACTCACCTCCCACTCCTCTTCCCTGTTATTTCTTTTCTGTTTTTTTCCCTTTCCTATGATGCCAAGCCT
GTGTTTTTTTTTTAACAGCTTTACCAAGAATTCCATATCAGATAATTTGCACACCATACAATTCACCCCT
TTAAACTGTACAATTTAGTGGCTTTTAGGATGTTCATAGAATTATTCAACCATTACCACAATTTTAGAAC
ATTTTTATTACCCTGGAAGAAACAGTTTAGCTGTCATTCACCAATCTTCTGGTCTTAGCCCTTGGCAAAC
ACTAATCTACTTTCTATTTATGGATTTGCCTATTGTAGACATTTGATAGAAATGGGATAATGTGTTGTCC
TCTGTGACTGGCTTCTTTCACTTAGCATAATCTTTTGGAGATTCATCCATGTATCTATGTATCAGTACTT
TTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCAATCTCTGCAACC
TTTGCCTCTAGTTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGTTGGGACTGTGGGCCCACACCAC
CACCTCTGGCTAATTTTTGTATTTTTAGTAGAGACTGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAGC
TCCTGACCTCAGGTGATCTGCCTGCCTCAGCCTCCCAAGTACTTGATTTTTGAAAACAGCCAAATAATAT
TCCATTGTATGGATATACTGCTTTTTATTTCTTTTCAATTGTTGATGGACATTTGGATTGTTTCCACTTT
TTTTTCCTTTTTTTGAGACAGGGTCCTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTGTAATCTCTGACC
TCCTAGGTTCAAGCTGTCCTCCTGCCTCAGCCTTCCTAGTAGTGGGACTACAAGTGTGCACCACTATGCC
TGGCTAATTTTGTAAAATGTTTGTAGAGATGGGGTTCTGCTCTGTTGCCCAGGCTTGTCTCAAATTCCTG
GCCTCAAGCACTTCTCCCATCTCATCCTCCCAAAGTGATAGGATTACAGGTGAGCACCACTGTGCCCAGC
CCACTTGTTGACTGTGGGCTGGGCACAGTGCTATATTATAATGCTGCTATGGCTGGGCGTGGTGGCTCAC
GCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACAAGGTCAGGAGATCGAGACCATCCTG
GCTAACACTGTGAAACCCCATCTCTACTAAAAATACAAAAAAAAAAAAAAAAAAAAAAAATTAGCCAGGC
GTGGTGGCAGGCGCCTGTAGTCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATGGCATGAACCCGGGAGG
CGGAGCTTGCGGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGCGAGACTCCGTCTCAAA
AAAAAAACAAAAACAAATAATGCTGCTATGAACATTTGTGTACAGGTTTTTGTGTGGACTCCTGCATACC
TGGGAGTGGAGCTACTGGGTCATATAGTAACTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCATGCTC
TGTTGCCCAGAGTGCAATGGCACAGTCTAGGCTCACTGCAACCTCCGCCTCCCAAGTTCAAATGATTCTC
CTGTCTCAGCTTCCCGAGTAGCTGGGACTATAGGCGTGTGCCACCACACCCAGCTAATTTTTGTATTTTT
AATAGAGATGGGGTTTCACCATGTTAGCCAGGTGGGCTCAAAACCCCGACCTCGTGATCTGCCTGCCTCA
GCCTCCCAAATTGCTGGGATTACAGGCGTGAGCCACTGCGTCCAGCCATATAGGAACTCTTTAACCATTT
GAGGAACTGCCAGATAATTTCCCACAATAACTGTACCTTTTATTTTATTTTATTTTATTTATTTTAAATA
GACATGGTTTCACTCTGTCGCCCAGGCTGGAGTGCAATGGCGTGATCTTGGCTCATTGCAACCTGTGCCT
CCCGGTTCAAATGATTCTCCTGTCTCACCCTCCCAAGTTGCTGGGATTATAGGTGTATGCCACCACACCT
GACTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGAC
CTCAGGTGATCCACCCACCTCGGCCTCCAATAGTGCTGGGATTAGAGGTGTGAGCTACTCTGCCCAGCCG
TGCACCAGTTCGTATTCCTACCAGCAGTGTCTGAGAGTTTCAATTCCTGTGGTTGTGAAATAAATCTCAG
ATATAATTTCATCCTAAAGTATTTTAGAATGTATTAATAAAGTATGAGGGATTTCTTTTTCAAATATAAA
CATAATGCCATTATAGTATCTACTAACATTAATTTTTAATATAATCAAATATTCAGTCAGTATTCAAATT
TCTTTCTTTTTTTTTTTTTTTTAATATAGAGACAGGGGCCTCACTCTGTCACCCAGAGTGGAGTGCAGTG
GCACAATCTCACTGAATCATTGAACTCCTGGTCTCAAGTGATCTTCCTGTTTCAACTTTCCAAGTATCCA
GGACTACAGGTGTGCGCCACCATGCCTGGCTAATTTTTTTTTTTTTTAATTTTTTGTAGAGACACGGTCT
TGCTATGTTGGCCAGGCTGGTCTCAAACTCTTGGCCTCGAGCAATCCTTCCACGTCAGCCTCGCAAAGCA
CTGGGATTATAGGCATGAACAACCGTGCCTGGCTTTGTGTTCAAATTTCTAATTGTCTTATAAATGTTAT
TTTAGGCCGGGTGCAGTGGCTCATGCCTGTAATTCCAGCACTTTGGGAGGCTCAGGTGGGCAGATCACTT
GAGATCAGGAGTTCGAGACCAGCTTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTA
GCTGGATGTAGTGGTGTGCACCTGTAATCCCAGCTCCTTGGGAAGCTGAGGCAGGAGAATTGCTTGAACC
TGGGAGACGGAGGTTGCAGTGAACCAAGATCGCACCACTGCACTCCAGCCTGGGCGACAGAGTAAGACTC
CATCTCAAAAAAAAAAACAAGTTATTTTTATGGTTTGTTTGAATCAGGATTGAAACAAGGTACACACATT
ATATGACTGATATGTCTTTTAAATCTTCTACTCTATAAATTTCACCTCCACACCTTTTTTTTACCTTTGT
TCTTCTTCTTCTTCTTTTTTTTTTTTTTGAAGAGATGGCATTGTGCTATGTTGCCCTGGCTGGTCTTGAA
CTCCTGGTCTCAATCAATCCTCCTGCTTTGGCCTCTCAAAGTGCTGGGTATTGAAGGCATGAGGCACTGT
GCCTGGCCCTCTTTCTTATTTTTTGCCTTATAATTTATATTTTGTAAAAAACAGGTCCTTTATCCTGTAG
CAGTTCCCAGAGTCTCAATTTTACTGACTACATTTGTGGTGTTGTTTAACACTTTGCCCCCTTCATTTCC
ATTAATTTGGTGTTGGATAATTTCCACAATAACTGCACCAGTTGCTCAGTCTATAACACTAATCAAGCAC
TGAATCCAACACCAAATTAATTTCCAGTATGTTACTTTCTAATTGTTACATACATTGTCATTCTAAGTTA
AGTGGCCTGTGAAATCAGTGTTAAAGAATAATAACTGGCTTTTTATAATAATGGAATAGAATACAATAGA
AAGTATCAGTGCACCCTATGTAATAAGAATAATTATTATTTTGTGAAACGTTTTTCCACCATGGATATGT
GTATTGGGAACTGGGTTAGTATGTGGAATATGGTTCTTAGGGGTTATGGTCAAATATTTGAAGAACACTG
TAATATGTAGGAATTTTTTTTAAATTTAAAAACAACATATGTTCTTTTTGAAGAATTATATAAAAAAAAT
AGAACCACTAGAAATAGGACTATCCTAAGCATATTAGTTTCTTGTGGCTACCATAGCAAATTGCCATAAA
CTGATGATGTAAAACAACACATTTATTCTGTCAGTTCTGGAGACCAGAAGTCTGAAATCAAGGAATTGGG
GCCACAAGCCCTCCAAAAGCTCTAAGGGAGAGTCCATTCCTTGCCTTTTCCAGCTTGCAGTGGCTGCTGG
CATTTCTTGGCATTCTTGGCCTGTTCCTTGATGTGACTCCAATCTCTGCCTCCATTCTCATGTCACTCAC
TCCTCTGGCTTCTCCTTTTCTGCGTGTTGCAGATCTCTTTCTGCTTTTCTCTCTGTTTTGTTGTTTGATA
CAGACTTTAACTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCAATCTTGGCTCACTGCAACCTCCGCCTCC
CAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTAGAACTACAGGCGCCTGCCACCACGCCCG
GCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACTATGTTGGCCAGGCTTGTCTTGAACTTCTGACC
TCGTGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGACACCACGCCAGGCCTCTG
CCTTTATCTTAGAAACGACACTTGTCATTGGATTTAGGGCCCGCCTAGATAACCCAGGGAGATCTTCTTA
TCTTAGGATCCTTAATTCTATCTGCAAAGACATTTTTGCTAAATAATGTTCACAGAGTCTGGCGATTAGG
ACATAGACTTCTCTTTTGGGGGCACCACCTTTCAACCCACTACACTAAGTGAAAAGTGAAATATTGATCT
CTACATCCCCCAACACTCCACCCAGGCTAGCATCCCAAATAGGGAAGCATTAAGATGTGAAAAATTCTGC
GGAACATTAGTGTAAAGCTTCTAGTGGAAAAATGATGACCAAGCATAACATTATGAGATAAGAGCATGAG
TAGGTTTAATATCCCCCTGGTATACGGCAGTGCAAGTATTGCCCTGTCTTCTCTGCTTGGTGAGGCCTAC
TTTTCCCCAGAATTAGAGTAAAATTATTCAGTATCCTTATATTGTCCTTACTTACTCCTGCAGGTTCATG
AATACTTAGGGGCAGAATGTAGGGAGGACATGCCATTCATTTCTTTGTGGTTTTTAGGTCAACTTCATAA
TATAAGAGAGGGATAATAAGTTAGCTTGTCATGCTACATGCTTGAAAGTCTGTCATCAGTACAGCCACCT
ATCCAGGCCAGACGGTTTCCCTGCCAGTTGGCCTCCATGGGACATTCTCCAGGAAACCAGCACATGAGCA
GGGAAAATCCCTGCCATTGTTGAGGCTATCGTTGTGGGTGAAAAGGGAATGTCCCTTGTGGTCCTGGAAT
CTCCCTGTGGCAAGCTCTGAATAGGGTATGATGAATTGAATAGGCCAGGAAGGATCCTGGCTCAGGGCTA
GAGTGGGATAGAAGGCCATTATGAAGTGAGAAATTAGAAAACTGGTGTCAGGATGGGGATCGCTATTTTA
CACACTTGAGAATTTAGAAAGGAATTACTGCACATTCCTAAACTGATTTTTTTTTTTTTTTTTTGACTGA
GGCTCGCTCTGTCACCCAGGCTGAAGTGCAGTGGCATGATCTTGGATCACTGCAACCTCCACTTCCGGGG
TTCAAGCGATTCTTCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCCTGCGCCTGGCTAATTTTT
GTATTTTTAACAGAGTCAGGGTTTCGCCATGTTAGCCAGGCTGGTCTGAAACTCCTGACCTCAGGTGATC
CACCTGCCTTAGCCTCCCAAAGTGCTGAGATTACACGCATGAGCCACCATGCCCAGCCAAACCAAATTTT
ACTAATTGATAAATCAAAGGACTGTTGTTGGTCATGTGATAAGAATAGCTAGAGCTGGGCGTGATGTCTC
ACACCTGTAATTCCAGCACTTTGGGAGGCCAAGATGGGAGGATCACTTGAAGCCAGGAGTTCGAGACCAG
CTTAGTCAACATAGCAAGACCCCATCTCTAAAAAAAAAAAAAATAATAAGTAAAATAAAAAGAATAGCTG
GGGACTAATGAGTGTGGACAGTTTGTAAAAATAAATTGAAATATTGTTAGTCTTCTTTATATTCCTAGAA
ATCGATGCTCCACATGCATCCCACAACTCCTTACAACTCCCCGATACAAAAATACTCACTGTAAGAAAAA
AACCCATAAAACCAAACTAAACCAGACAATAGAAATCCCAATAATCTCATTACACAAAGAAAAGCCCCTA
TAAGCATTTTGTGTAATCCTCTAATAGTACATTTCTGTTTTCATCTAAAGTACTTTCATTTGAGGCTGGG
CTCAGTGGCTCACACTTGTATCTCACCACTTTGGGAGGCTGAGGCAGGAGAATCTTAAGGCCAGGAGTTT
GAGAACAGCCTGGGCAACATAGTGAGATCCTATCTCTACAAAAAGTAAAAAATTAGCTGGGTGTGATGGT
GTGTGCCTGTGGCCTGGCTGTTTAGGAGGATTGCTTGAGCCCAAAAGTTTGAGGCTGCGGTGCATTATGA
TCGCTCCACTACGCTCCAGCCTGGGTGACAGCGAGACCCTGTCTCATAAATTAAAAAATGAATAAATGAA
TGTACTTTCATTTGAACAAACCAGTGTTACTGCTGAAACATTTATTTCTGTAATGACCCTTGTCTTCCTT
TCTTGTACAGGAACCAGTAGATCCTCTAAAGGAAGAAGCCTTATTGGTAAGGTTGATGGCACATCCCACG
TCACTGGAAAAGGAGTTACAGTTGAAACAGTCTTTTCTGTGGATGAGTTTTCTGCATCTGTCCTCACTGG
AAAACTGACCACTGTCTTCCTTCCAATTGTCTACACAATTGTGTTTGTGGTGGGTTTGCCAAGTAACGGC
ATGGCCCTGTGGGTCTTTCTTTTCCGAACTAAGAAGAAGCACCCTGCTGTGATTTACATGGCCAATCTGG
CCTTGGCTGACCTCCTCTCTGTCATCTGGTTCCCCTTGAAGATTGCCTATCACATACATGGCAACAACTG
GATTTATGGGGAAGCTCTTTGTAATGTGCTTATTGGCTTTTTCTATGGCAACATGTACTGTTCCATTCTC
TTCATGACCTGCCTCAGTGTGCAGAGGTATTGGGTCATCGTGAACCCCATGGGGCACTCCAGGAAGAAGG
CAAACATTGCCATTGGCATCTCCCTGGCAATATGGCTGCTGATTCTGCTGGTCACCATTCCTTTGTATGT
CGTGAAGCAGACCATCTTCATTCCTGCCCTGAACATCACGACCTGTCATGATGTTTTGCCTGAGCAGCTC
TTGGTGGGAGACATGTTCAATTACTTCCTCTCTCTGGCCATTGGGGTCTTTCTGTTCCCAGCCTTCCTCA
CAGCCTCTGCCTATGTGCTGATGATCAGAATGCTGCGATCTTCTGCCATGGATGAAAACTCAGAGAAGAA
AAGGAAGAGGGCCATCAAACTCATTGTCACTGTCCTGGCCATGTACCTGATCTGCTTCACTCCTAGTAAC
CTTCTGCTTGTGGTGCATTATTTTCTGATTAAGAGCCAGGGCCAGAGCCATGTCTATGCCCTGTACATTG
TAGCCCTCTGCCTCTCTACCCTTAACAGCTGCATCGACCCCTTTGTCTATTACTTTGTTTCACATGATTT
CAGGGATCATGCAAAGAACGCTCTCCTTTGCCGAAGTGTCCGCACTGTAAAGCAGATGCAAGTATCCCTC
ACCTCAAAGAAACACTCCAGGAAATCCAGCTCTTACTCTTCAAGTTCAACCACTGTTAAGACCTCCTATT
GAGTTTTCCAGGTCCTCAGATGGGAATTGCACAGTAGGATGTGGAACCTGTTTAATGTTATGAGGACGTG
TCTGTTATTTCCTAATCAAAAAGGTCTCACCACATACCATGTGGATGCAGCACCTCTCAGGATTGCTAGG
AGCTCCCCTGTTTGCATGAGAAAAGTAGTCCCCCAAATTAACATCAGTGTCTGTTTCAGAATCTCTCTAC
TCAGATGACCCCAGAAACTGAACCAACAGAAGCAGACTTTTCAGAAGATGGTGAAGACAGAAACCCAGTA
ACTTGCAAAAAGTAGACTTGGTGTGAAGACTCACTTCTCAGCTGAAATTATATATATACACATATATATA
TTTTACATCTGGGATCATGATAGACTTGTTAGGGCTTCAAGGCCCTCAGAGATGATCAGTCCAACTGAAC
GACCTTACAAATGAGGAAACCAAGATAAATGAGCTGCCAGAATCAGGTTTCCAATCAACAGCAGTGAGTT
GGGATTGGACAGTAGAATTTCAATGTCCAGTGAGTGAGGTTCTTGTACCACTTCATCAAAATCATGGATC
TTGGCTGGGTGCGGTGCCTCATGCCTGTAATCCTAGCACTTTGGGAGGCTGAGGCAGGCAATCACTTGAG
GTCAGGAGTTCGAGACCAGCCTGGCCATCATGGCGAAACCTCATCTCTACTAAAAATACAAAAGTTAACC
AGGTGTGTGGTGCACGTTTGTAATCCCAGTTACTCAGGAGGCTGAGGCACAAGAATTGAGTATCACTTTA
ACTCAGGAGGCAGAGGTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCTTGGGTGATAAAATAAAA
TAAAATAGTCGTGAATCTTGTTCAAAATGCAGATTCCTCAGATTCAATAATGAGAGCTCAGACTGGGAAC
AGGGCCCAGGAATCTGTGTGGTACAAACCTGCATGGTGTTTATGCACACAGAGATTTGAGAACCATTGTT
CTGAATGCTGCTTCCATTTGACAAAGTGCCGTGATAATTTTTGAAAAGAGAAGCAAACAATGGTGTCTCT
TTTATGTTCAGCTTATAATGAAATCTGTTTGTTGACTTATTAGGACTTTGAATTATTTCTTTATTAACCC
TCTGAGTTTTTGTATGTATTATTATTAAAGAAAAATGCAATCAGGATTTTAAACATGTAAATACAAATTT
TGTATAACTTTTGATGACTTCAGTGAAATTTTCAGGTAGTCTGAGTAATAGATTGTTTTGCCACTTAGAA
TAGCATTTGCCACTTAGTATTTTAAAAAATAATTGTTGGAGTATTTATTGTCAGTTTTGTTCACTTGTTA
TCTAATACAAAATTATAAAGCCTTCAGAGGGTTTGGACCACATCTCTTTGGAAAATAGTTTGCAACATAT
TTAAGAGATACTTGATGCCAAAATGACTTTATACAACGATTGTATTTGTGACTTTTAAAAATAATTATTT
TATTGTGTAATTGATTTATAAATAACAAAATTTTTTTTACAACTTA
|
| Protein Name |
PAR2_HUMAN |
| Length |
397 |
| Moltype |
AA |
| Topology |
linear |
| Division |
PRI |
| Update Date |
12-OCT-2022 |
| Create Date |
01-OCT-1996 |
| Definition |
RecName: Full=Proteinase-activated receptor 2; Short=PAR-2; AltName: Full=Coagulation factor II receptor-like 1; AltName: Full=G-protein coupled receptor 11; AltName: Full=Thrombin receptor-like 1; Contains: RecName: Full=Proteinase-activated receptor 2, alternate cleaved 1; Contains: RecName: Full=Proteinase-activated receptor 2, alternate cleaved 2; Flags: Precursor |
| Primary Accession |
P55085 |
| Accession Version |
P55085.1 |
| Other SeqIDs |
sp|P55085.1|PAR2_HUMAN,gi|1709580 |
| Organism |
Homo sapiens |
| Taxonomy |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo |
| Comment |
On or before Jul 13, 2012 this sequence version replaced gi:74754947, gi:2136063.; [FUNCTION] Receptor for trypsin and trypsin-like enzymes coupled to G proteins (PubMed:28445455). Its function is mediated through the activation of several signaling pathways including phospholipase C (PLC), intracellular calcium, mitogen-activated protein kinase (MAPK), I-kappaB kinase/NF-kappaB and Rho (PubMed:28445455). Can also be transactivated by cleaved F2R/PAR1. Involved in modulation of inflammatory responses and regulation of innate and adaptive immunity, and acts as a sensor for proteolytic enzymes generated during infection. Generally is promoting inflammation. Can signal synergistically with TLR4 and probably TLR2 in inflammatory responses and modulates TLR3 signaling. Has a protective role in establishing the endothelial barrier; the activity involves coagulation factor X. Regulates endothelial cell barrier integrity during neutrophil extravasation, probably following proteolytic cleavage by PRTN3 (PubMed:23202369). Proposed to have a bronchoprotective role in airway epithelium, but also shown to compromise the airway epithelial barrier by interrupting E-cadherin adhesion (PubMed:10086357). Involved in the regulation of vascular tone; activation results in hypotension presumably mediated by vasodilation. Associates with a subset of G proteins alpha subunits such as GNAQ, GNA11, GNA14, GNA12 and GNA13, but probably not with G(o)-alpha, G(i) subunit alpha-1 and G(i) subunit alpha-2. However, according to PubMed:21627585 can signal through G(i) subunit alpha. Believed to be a class B receptor which internalizes as a complex with arrestin and traffic with it to endosomal vesicles, presumably as desensitized receptor, for extended periods of time. Mediates inhibition of TNF-alpha stimulated JNK phosphorylation via coupling to GNAQ and GNA11; the function involves dissociation of RIPK1 and TRADD from TNFR1. Mediates phosphorylation of nuclear factor NF-kappa-B RELA subunit at 'Ser-536'; the function involves IKBKB and is predominantly independent of G proteins. Involved in cellular migration. Involved in cytoskeletal rearrangement and chemotaxis through beta-arrestin-promoted scaffolds; the function is independent of GNAQ and GNA11 and involves promotion of cofilin dephosphorylation and actin filament severing. Induces redistribution of COPS5 from the plasma membrane to the cytosol and activation of the JNK cascade is mediated by COPS5. Involved in the recruitment of leukocytes to the sites of inflammation and is the major PAR receptor capable of modulating eosinophil function such as pro-inflammatory cytokine secretion, superoxide production and degranulation. During inflammation promotes dendritic cell maturation, trafficking to the lymph nodes and subsequent T-cell activation. Involved in antimicrobial response of innate immune cells; activation enhances phagocytosis of Gram-positive and killing of Gram-negative bacteria. Acts synergistically with interferon-gamma in enhancing antiviral responses. Implicated in a number of acute and chronic inflammatory diseases such as of the joints, lungs, brain, gastrointestinal tract, periodontium, skin, and vascular systems, and in autoimmune disorders. {ECO:0000269|PubMed:10086357, ECO:0000269|PubMed:10725339, ECO:0000269|PubMed:11413129, ECO:0000269|PubMed:11441110, ECO:0000269|PubMed:11447194, ECO:0000269|PubMed:11714832, ECO:0000269|PubMed:12832443, ECO:0000269|PubMed:15155775, ECO:0000269|PubMed:16359518, ECO:0000269|PubMed:16410250, ECO:0000269|PubMed:16478888, ECO:0000269|PubMed:16714334, ECO:0000269|PubMed:17404307, ECO:0000269|PubMed:17500066, ECO:0000269|PubMed:18424071, ECO:0000269|PubMed:18453611, ECO:0000269|PubMed:18474671, ECO:0000269|PubMed:18622013, ECO:0000269|PubMed:19494303, ECO:0000269|PubMed:19781631, ECO:0000269|PubMed:19864598, ECO:0000269|PubMed:19865078, ECO:0000269|PubMed:20826780, ECO:0000269|PubMed:21501162, ECO:0000269|PubMed:23202369, ECO:0000269|PubMed:28445455}.; ACTIVITY REGULATION: Activated upon interaction by mucunain, a cowhage (Mucuna pruriens) plant cysteine proteinase. {ECO:0000269|PubMed:18434511}.; [SUBUNIT] Interacts with TLR4, COPS5 and TMED2. Interacts with GNAQ, GNA11, GNA12, GNA13 and GNA14 (By similarity). {ECO:0000250}.; [INTERACTION] P55085; P16615: ATP2A2; NbExp=2; IntAct=EBI-4303189, EBI-358933; P55085; P22681: CBL; NbExp=3; IntAct=EBI-4303189, EBI-518228; P55085; Q92905: COPS5; NbExp=8; IntAct=EBI-4303189, EBI-594661; P55085; Q14868: EPR-1; NbExp=4; IntAct=EBI-4303189, EBI-4309771; P55085; P13726: F3; NbExp=2; IntAct=EBI-4303189, EBI-1040727; P55085; P0DMV9: HSPA1B; NbExp=2; IntAct=EBI-4303189, EBI-14100688; P55085; P04156: PRNP; NbExp=3; IntAct=EBI-4303189, EBI-977302; P55085; Q15363: TMED2; NbExp=6; IntAct=EBI-4303189, EBI-998485; P55085; P29066: Arrb1; Xeno; NbExp=6; IntAct=EBI-4303189, EBI-4303019.; [SUBCELLULAR LOCATION] Cell membrane; Multi-pass membrane protein.; [TISSUE SPECIFICITY] Widely expressed in tissues with especially high levels in pancreas, liver, kidney, small intestine, and colon (PubMed:7556175, PubMed:8615752). Moderate expression is detected in many organs, but none in brain or skeletal muscle (PubMed:7556175, PubMed:8615752). Expressed in endothelial cells (PubMed:23202369). {ECO:0000269|PubMed:23202369, ECO:0000269|PubMed:7556175, ECO:0000269|PubMed:8615752}.; [PTM] A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand (PubMed:10831593, PubMed:19864598, PubMed:9020112, PubMed:10805786, PubMed:16478888). Activating serine proteases include trypsin, mast cell tryptase, coagulation factors VII and Xa, myeloblastin/PRTN3 and membrane-type serine protease 1/ST14 (PubMed:10831593, PubMed:19864598, PubMed:9020112, PubMed:10805786, PubMed:16478888, PubMed:23202369). Subsequent cleavage by serine proteases, including neutrophil elastase and cathepsin G, leads to receptor deactivation (PubMed:12594060). At least in part, implicated proteases are also shown to activate the receptor; the glycosylation status of the receptor is thought to contribute to the difference (PubMed:12171601). In addition to conventional trypsin-like proteases activated by other proteases and glycosidases derived from bacteria, fungi and insects (PubMed:11447194, PubMed:11441110, PubMed:17404307, PubMed:18474671, PubMed:19864598). Activated by serine protease allergens such as dust mite Der p3 and Der p9 and mold Pen c13 (PubMed:11441110, PubMed:17404307). Activated by P.gingivalis arginine-specific (trypsin-like) cysteine proteinases called gingipains (PubMed:11447194). Activated by S.griseus exogenous chitinase (PubMed:18474671). Activated by A.alternata aspartate protease; the cleavage generates non-conventional processed forms (PubMed:19864598). {ECO:0000269|PubMed:10805786, ECO:0000269|PubMed:10831593, ECO:0000269|PubMed:11441110, ECO:0000269|PubMed:11447194, ECO:0000269|PubMed:12171601, ECO:0000269|PubMed:12594060, ECO:0000269|PubMed:16478888, ECO:0000269|PubMed:17404307, ECO:0000269|PubMed:18474671, ECO:0000269|PubMed:19864598, ECO:0000269|PubMed:23202369, ECO:0000269|PubMed:9020112}.; [PTM] N-glycosylated and sialylated. {ECO:0000269|PubMed:12171601}.; [PTM] Multiple phosphorylated on serine and threonine residues in the cytoplasmic region upon receptor activation; required for receptor desensitization and recruitment of beta-arrestin. {ECO:0000269|PubMed:19815543}.; [PTM] Monoubiquitinated by CBL at the plasma membrane and in early endosomes; not required for receptor endocytosis but for translocation to late endosomes or lysosomes. Deubiquitination involves STAMBP and USP8; required for lysosomal trafficking and receptor degradation.; [MISCELLANEOUS] Synthetic PAR agonist peptides (APs) that mimic the first six amino acids of the newly formed N-terminus activate the native, uncleaved receptor nonenzymatically by binding directly to the corresponding second extracellular loop to mediate signaling.; [SIMILARITY] Belongs to the G-protein coupled receptor 1 family. {ECO:0000255|PROSITE-ProRule:PRU00521}.; [WEB RESOURCE] Name=Wikipedia; Note=Protease-activated receptor entry; URL='https://en.wikipedia.org/wiki/Protease-activated_receptor'.; [WEB RESOURCE] Name=SeattleSNPs; URL='http://pga.gs.washington.edu/data/f2rl1/'. |
| Source Db |
UniProtKB: locus PAR2_HUMAN, accession P55085;; class: standard.; extra accessions:Q13317,Q13346,Q53XJ8; created: Oct 1, 1996.; sequence updated: Oct 1, 1996.; annotation updated: Oct 12, 2022.; xrefs: Z49993.1, CAA90290.1, Z49994.1, U34038.1, AAB47871.1, AY336105.1, AAP97012.1, AF400075.1, AAK77914.1, BT009856.1, AAP88858.1, CH471084.1, EAW95782.1, BC012453.1, AAH12453.1, BC018130.1, AAH18130.1, U36753.1, AAA90957.1, S66518, NP_005233.3, 5NDD_A, 5NDZ_A, 5NJ6_A; xrefs (non-sequence databases): CCDS:CCDS4033.1, PDBsum:5NDD, PDBsum:5NDZ, PDBsum:5NJ6, AlphaFoldDB:P55085, SMR:P55085, BioGRID:108449, DIP:DIP-42044N, IntAct:P55085, MINT:P55085, STRING:9606.ENSP00000296677, BindingDB:P55085, ChEMBL:CHEMBL5963, GuidetoPHARMACOLOGY:348, TCDB:9.A.14.13.12, GlyGen:P55085, iPTMnet:P55085, PhosphoSitePlus:P55085, SwissPalm:P55085, BioMuta:F2RL1, DMDM:1709580, jPOST:P55085, MassIVE:P55085, MaxQB:P55085, PaxDb:P55085, PeptideAtlas:P55085, PRIDE:P55085, ProteomicsDB:56787, ABCD:P55085, Antibodypedia:4569, DNASU:2150, Ensembl:ENST00000296677.5, Ensembl:ENSP00000296677.4, Ensembl:ENSG00000164251.5, GeneID:2150, KEGG:hsa:2150, UCSC:uc003keo.4, CTD:2150, DisGeNET:2150, GeneCards:F2RL1, HGNC:3538, HPA:ENSG00000164251, MIM:600933, neXtProt:NX_P55085, PharmGKB:PA27947, VEuPathDB:HostDB:ENSG00000164251, eggNOG:ENOG502QR8S, HOGENOM:CLU_009579_8_2_1, InParanoid:P55085, OrthoDB:892946at2759, PhylomeDB:P55085, TreeFam:TF330775, PathwayCommons:P55085, Reactome:R-HSA-375276, Reactome:R-HSA-416476, SignaLink:P55085, SIGNOR:P55085, BioGRID-ORCS:2150, ChiTaRS:F2RL1, GeneWiki:Protease_activated_receptor_2, GenomeRNAi:2150, Pharos:P55085, PRO:PR:P55085, Proteomes:UP000005640, RNAct:P55085, Bgee:ENSG00000164251, ExpressionAtlas:P55085, Genevisible:P55085, GO:0005769, GO:0005794, GO:0005887, GO:0005886, GO:0031143, GO:0004930, GO:0001965, GO:0031681, GO:0002020, GO:0038023, GO:0005102, GO:0015057, GO:0007596, GO:0045217, GO:0051607, GO:0061028, GO:0007186, GO:0006954, GO:0045087, GO:0050900, GO:0070661, GO:0097029, GO:0032682, GO:0046329, GO:0034140, GO:0010804, GO:0042119, GO:0030836, GO:0030335, GO:0032722, GO:0050921, GO:0002720, GO:0007204, GO:0051482, GO:0043311, GO:0070374, GO:0003104, GO:0043547, GO:0043123, GO:0032729, GO:0032731, GO:0032733, GO:0032755, GO:0032757, GO:0046330, GO:0002690, GO:0070963, GO:0060100, GO:0014068, GO:0050927, GO:0031274, GO:1900135, GO:0035025, GO:0032930, GO:0034137, GO:0034141, GO:0034145, GO:0045944, GO:0030193, GO:2000341, GO:0043122, GO:0046328, GO:0002286, GO:0042311, InterPro:IPR000276, InterPro:IPR017452, InterPro:IPR002281, InterPro:IPR003912, Pfam:PF00001, PRINTS:PR00237, PRINTS:PR01428, PRINTS:PR01152, PROSITE:PS50262 |
| Sequence |
mrspsaawllgaaillaaslscsgtiqgtnrsskgrsligkvdgtshvtgkgvtvetvfsvdefsasvltgklttvflpivytivfvvglpsngmalwvflfrtkkkhpaviymanlaladllsviwfplkiayhihgnnwiygealcnvligffygnmycsilfmtclsvqrywvivnpmghsrkkaniaigislaiwllillvtiplyvvkqtifipalnittchdvlpeqllvgdmfnyflslaigvflfpafltasayvlmirmlrssamdensekkrkraiklivtvlamylicftpsnlllvvhyfliksqgqshvyalyivalclstlnscidpfvyyfvshdfrdhaknallcrsvrtvkqmqvsltskkhsrksssyssssttvktsy |
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