Canarypox virus 44088 Canary Pox Passeriform (song) birds (Tulman et al., 2004). Canarypox virus (CNPV) is an avipoxvirus and etiologic agent of canarypox, a disease of birds both in the wild and in commercial aviaries, where significant losses result. Canarypox has been described broadly as the poxviral disease of passeriform (song) birds, efficiently causing disease in passerine hosts compared to galliform (domestic fowl) and columbiform (pigeon) hosts. However, passerine host preferences exist, and current International Committee on Taxonomy of Viruses classification differentiates between CNPV and several other passerine isolates. CNPV produces clinical signs similar to generalized poxviral infections of other birds, including both cutaneous and diptheretic disease forms caused by the prototypical galliform avipoxvirus, fowlpox virus (FWPV), and including proliferative and necrotic changes in epithelial tissues of the dermis, notably around the eyes and commissures of the beak, feet, and respiratory tract. Canarypox, however, is generally associated with higher mortality rates than seen in fowlpox, commonly approaching 100%, and may occur without characteristic skin lesions. Histologically and ultrastructurally, CNPV undergoes morphogenic stages similar to FWPV and other chordopoxviruses (ChPV), causing type A and B intracytoplasmic inclusions in epithelial and mononuclear cells of permissive hosts; however, CNPV may have a broader tissue tropism than FWPV (Tulman et al., 2004). Baboon Papio cynocephalus 9556 Bank vole Clethrionomys glareolus 447135 Bear Ursus americanus 9643 Birds Passeroidea 175121 Brown Trout Salmo trutta 8032 Buffalo Bison bison 9901 Carnivores Vulpes 9625 Cat Felis catus 9685 Catfishes Siluriformes 7995 Cattle Bos taurus 9913 Chicken Gallus gallus 9031 Chimpanzee Pan troglodytes 9598 chinchillas Chinchillidae 10150 Copper Pheasant Syrmaticus soemmerringii 9067 Deer Cervus elaphus 9860 Deer mouse Peromyscus maniculatus 10042 Dog Canis familiaris 9615 Ducks Anas 8835 Ferret Mustela putorius furo 9669 Fish Hyperotreti 117565 Gerbil Gerbillina 10045 Goat Capra hircus 9925 Gray wolf Canis lupus 9612 Guinea pig Cavia porcellus 10141 Hamster Mesocricetus auratus 10036 Horse Equus caballus 9796 Human Homo sapiens 9606 Macaque Macaca fascicularis 9541 Mongolian Gerbil Meriones unguiculatus 10047 Monkey Platyrrhini 9479 Mouse Mus musculus 10090 None None Parrot Psittacidae 9224 Pig Sus scrofa 9823 Rabbit Oryctolagus cuniculus 9986 Rainbow trout Oncorhynchus mykiss 8022 Rat Rattus 10114 Raven Corvus corax 56781 sei whale Balaenoptera borealis 9768 Sheep Ovis aries 9940 Squirrel Spermophilus richardsonii 37591 Tree shrew Tupaiidae 9393 Trouts, salmons & chars Salmoninae 504568 Turkey Meleagris gallopavo 9103 Vole Microtus ochrogaster 79684 Water buffalo Bubalus bubalis 391902 Canary Pox Modified Live Virus Vaccine (USDA: 1623.10) Biomune Company VO_0001530 Live, attenuated vaccine Licensed USA