Equine rotavirus 10937 Rotaviral Diarrhea Rotavirus, a non-enveloped RNA virus, is a major infectious cause of foal diarrhea and has been documented to cause 50% or more of foal diarrhea cases in some areas. While rotavirus diarrhea morbidity can be high (50% of susceptible foals), mortality is low (<1%) with veterinary intervention. Equine rotavirus is transmitted via the fecal-oral route and damages the small intestinal villi resulting in cellular destruction, maldigestion, malabsorption, and diarrhea. As many as 70% of all foals in the United States will have at least one diarrheal episode prior to weaning. Mare owners need to be aware that strict biosecurity and disinfection during the foaling season also mitigates the morbidity associated with most types of infectious foal diarrheas and other contagious diseases. Vaccination of mares results in a significant increase in foals’ rotavirus antibody titers. Field trials of rotavirus vaccination in pregnant mares have shown a decrease in incidence and severity of foal diarrhea on farms that historically had annual rotaviral diarrhea cases. Other studies have shown increased rotavirus antibody in vaccinated mares’ colostrum (AAEP: Rotaviral Diarrhea). Baboon Papio cynocephalus 9556 Bank vole Clethrionomys glareolus 447135 Bear Ursus americanus 9643 Birds Passeroidea 175121 Brown Trout Salmo trutta 8032 Buffalo Bison bison 9901 Carnivores Vulpes 9625 Cat Felis catus 9685 Catfishes Siluriformes 7995 Cattle Bos taurus 9913 Chicken Gallus gallus 9031 Chimpanzee Pan troglodytes 9598 chinchillas Chinchillidae 10150 Copper Pheasant Syrmaticus soemmerringii 9067 Deer Cervus elaphus 9860 Deer mouse Peromyscus maniculatus 10042 Dog Canis familiaris 9615 Ducks Anas 8835 Ferret Mustela putorius furo 9669 Fish Hyperotreti 117565 Gerbil Gerbillina 10045 Goat Capra hircus 9925 Gray wolf Canis lupus 9612 Guinea pig Cavia porcellus 10141 Hamster Mesocricetus auratus 10036 Horse Equus caballus 9796 Human Homo sapiens 9606 Macaque Macaca fascicularis 9541 Mongolian Gerbil Meriones unguiculatus 10047 Monkey Platyrrhini 9479 Mouse Mus musculus 10090 None None Parrot Psittacidae 9224 Pig Sus scrofa 9823 Rabbit Oryctolagus cuniculus 9986 Rainbow trout Oncorhynchus mykiss 8022 Rat Rattus 10114 Raven Corvus corax 56781 sei whale Balaenoptera borealis 9768 Sheep Ovis aries 9940 Squirrel Spermophilus richardsonii 37591 Tree shrew Tupaiidae 9393 Trouts, salmons & chars Salmoninae 504568 Turkey Meleagris gallopavo 9103 Vole Microtus ochrogaster 79684 Water buffalo Bubalus bubalis 391902 Equine Rotavirus Killed Virus Vaccine (USDA: 1E15.20) Wyeth VO_0001783 Inactivated or "killed" vaccine Licensed USA AAEP: Rotaviral Diarrhea website http://www.aaep.org/rotaviral_diarrhea.htm