Feline panleukopenia virus 10786 The virus primarily attacks the lining of the gastrointestinal tract, causing internal ulceration and, ultimately, total sloughing of the intestinal epithelium. This results in profuse and usually bloody diarrhea, severe dehydration, malnutrition, anemia, and often death. The virus causes a decrease in the cat's white blood cells, thus compromising its immune system. Typically, it also causes a decrease in hematocrit and platelet counts on a complete blood count (Wiki: Feline Panleukopenia). Feline Distemper Antibodies are critical in the immune response to FPV, and can protect kittens from fatal infection. Active immunity is solid and long lasting and can be achieved through the use of either inactivated or modified live virus vaccines (Truyen et al., 2009). FPV can infect felids, raccoons, mink and foxes (Truyen et al., 2009). Feline panleukopenia, commonly known as feline distemper, is a viral infection affecting cats, caused by feline parvovirus, a close relative of canine parvovirus. It is not related to canine distemper (Wiki: Feline Panleukopenia). Feline panleukopenia virus (FPV) is a non-enveloped virus which is resistant to physical factors and chemical substances. The virus can remain infectious for months outside of a host and is highly contagious (Truyen et al., 2009). Baboon Papio cynocephalus 9556 Bank vole Clethrionomys glareolus 447135 Bear Ursus americanus 9643 Birds Passeroidea 175121 Brown Trout Salmo trutta 8032 Buffalo Bison bison 9901 Carnivores Vulpes 9625 Cat Felis catus 9685 Catfishes Siluriformes 7995 Cattle Bos taurus 9913 Chicken Gallus gallus 9031 Chimpanzee Pan troglodytes 9598 chinchillas Chinchillidae 10150 Copper Pheasant Syrmaticus soemmerringii 9067 Deer Cervus elaphus 9860 Deer mouse Peromyscus maniculatus 10042 Dog Canis familiaris 9615 Ducks Anas 8835 Ferret Mustela putorius furo 9669 Fish Hyperotreti 117565 Gerbil Gerbillina 10045 Goat Capra hircus 9925 Gray wolf Canis lupus 9612 Guinea pig Cavia porcellus 10141 Hamster Mesocricetus auratus 10036 Horse Equus caballus 9796 Human Homo sapiens 9606 Macaque Macaca fascicularis 9541 Mongolian Gerbil Meriones unguiculatus 10047 Monkey Platyrrhini 9479 Mouse Mus musculus 10090 None None Parrot Psittacidae 9224 Pig Sus scrofa 9823 Rabbit Oryctolagus cuniculus 9986 Rainbow trout Oncorhynchus mykiss 8022 Rat Rattus 10114 Raven Corvus corax 56781 sei whale Balaenoptera borealis 9768 Sheep Ovis aries 9940 Squirrel Spermophilus richardsonii 37591 Tree shrew Tupaiidae 9393 Trouts, salmons & chars Salmoninae 504568 Turkey Meleagris gallopavo 9103 Vole Microtus ochrogaster 79684 Water buffalo Bubalus bubalis 391902 Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 15B5.20) Wyeth VO_0001843 Inactivated or "killed" vaccine Licensed USA Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 15B5.21) Wyeth VO_0001844 Inactivated or "killed" vaccine Licensed USA Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Modified Live & Killed Virus Vaccine (USDA: 15B9.20) Intervet Inc. VO_0001845 Live, attenuated vaccine; Inactivated or "killed" vaccine Licensed USA Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Modified Live & Killed Virus Vaccine (USDA: 15B9.21) Wyeth VO_0001846 Live, attenuated vaccine; Inactivated or "killed" vaccine Licensed USA Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 1559.20) Wyeth VO_0001847 Inactivated or "killed" vaccine Licensed USA Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 1559.23) Wyeth VO_0001848 Inactivated or "killed" vaccine Licensed USA Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live & Killed Virus, Killed Chlamydia Vaccine (USDA: 1559.2C) Wyeth VO_0001849 Live, attenuated vaccine; Inactivated or "killed" vaccine Licensed USA Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live & Killed Virus, Modified Live Chlamydia Vaccine (USDA: 1559.2B) Intervet Inc. VO_0001850 Live, attenuated vaccine; Inactivated or "killed" vaccine Licensed USA Feline Panleukopenia Killed Virus Vaccine (USDA: 1565.20) Intervet Inc. VO_0001550 Inactivated or "killed" vaccine Licensed USA Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.00) Intervet Inc. VO_0001551 Live, attenuated vaccine Licensed USA Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.20) Intervet Inc., Pfizer, Inc. VO_0001552 Live, attenuated vaccine Licensed USA Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.21) Boehringer Ingelheim Vetmedica, Inc. VO_0001553 Live, attenuated vaccine Licensed USA Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.23) Heska Corporation VO_0001554 Live, attenuated vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 16D5.20) Wyeth VO_0001853 Inactivated or "killed" vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 16D5.23) Wyeth VO_0001854 Inactivated or "killed" vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia Modified Live & Killed Virus Vaccine (USDA: 16D9.20) Intervet Inc. VO_0001855 Live, attenuated vaccine; Inactivated or "killed" vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.20) Wyeth, Intervet Inc., Pfizer, Inc. VO_0001856 Live, attenuated vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.22) Wyeth, Intervet Inc., Heska Corporation VO_0001857 Live, attenuated vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.23) Intervet Inc. VO_0001858 Live, attenuated vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.24) Intervet Inc. VO_0001859 Live, attenuated vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D8.20) Boehringer Ingelheim Vetmedica, Inc. VO_0001860 Live, attenuated vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D8.21) Merial, Inc. VO_0001861 Live, attenuated vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 16E5.20) Wyeth VO_0001862 Inactivated or "killed" vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 16E5.23) Wyeth VO_0001863 Inactivated or "killed" vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Killed Chlamydia Vaccine (USDA: 16E6.20) Wyeth VO_0001864 Live, attenuated vaccine; Inactivated or "killed" vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16E1.20) Wyeth, Intervet Inc., Pfizer, Inc. VO_0001865 Live, attenuated vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16E1.24) Intervet Inc. VO_0001866 Live, attenuated vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16E8.20) Merial, Inc. VO_0001867 Live, attenuated vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci-Rabies Modified Live & Killed Virus, Modified Live Chlamydia Vaccine (USDA: 1619.20) Merial, Inc. VO_0001868 Live, attenuated vaccine; Inactivated or "killed" vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci-Rabies Modified Live Virus and Chlamydia, Canarypox Vector Vaccine (USDA: 1619.R1) Merial, Inc. VO_0001869 Live, attenuated vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia-Rabies Modified Live & Killed Virus Vaccine (USDA: 16T9.20) Intervet Inc., Merial, Inc. VO_0001870 Live, attenuated vaccine; Inactivated or "killed" vaccine Licensed USA Feline Rhinotracheitis-Calici-Panleukopenia-Rabies Modified Live Virus, Canarypox Vector Vaccine (USDA: 16T9.R0) Merial, Inc. VO_0001871 Live, attenuated vaccine Licensed USA Truyen et al., 2009 journal Truyen U, Addie D, Belák S, Boucraut-Baralon C, Egberink H, Frymus T, Gruffydd-Jones T, Hartmann K, Hosie MJ, Lloret A, Lutz H, Marsilio F, Pennisi MG, Radford AD, Thiry E, Horzinek MC 2009 11 7 538-546 Journal of feline medicine and surgery Wiki: Feline Panleukopenia website http://en.wikipedia.org/wiki/Feline_Panleukopenia Yang et al., 2008 journal Yang S, Xia X, Qiao J, Liu Q, Chang S, Xie Z, Ju H, Zou X, Gao Y 2008 26 11 1482-1487 Vaccine