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Vaccine Detail
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TRUMENBA |
| Vaccine Information |
- Vaccine Name: TRUMENBA
- Target Pathogen: Neisseria meningitidis
- Target Disease: Meningitis
- Product Name: Meningococcal Group B Vaccine
- Tradename: TRUMENBA
- Manufacturer: Pfizer Inc.
- Type: Subunit vaccine
- Status: Licensed
- Location Licensed: USA
- Host Species for Licensed Use: Human
- Immunization Route: Intramuscular injection (i.m.)
- Storage: Store at 2°C to 8°C (36°F to 46°F), do not freeze.
- Approved Age for Licensed Use: 10 to 25 years of age.
- Description: Trumenba is a sterile suspension composed of two recombinant lipidated factor H binding protein (fHBP) variants from N. meningitidis serogroup B, one from fHBP subfamily A and one from subfamily B (A05 and B01, respectively). The proteins are individually produced in E. coli. Production strains are grown in defined fermentation growth media to a specific density. The recombinant proteins are extracted from the production strains and purified through a series of column chromatography steps. Polysorbate 80 (PS80) is added to the drug substances and is present in the final drug product. (FDA: TRUMENBA)
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| Host Response |
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| References |
FDA: TRUMENBA: FDA: TRUMENBA vaccine information [https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM421139.pdf]
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