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Vaccine Detail
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Recombinant Fowlpox-gp100p209 Vaccine |
| Vaccine Information |
- Vaccine Name: Recombinant Fowlpox-gp100p209 Vaccine
- Target Pathogen: Cancer
- Target Disease: Cancer
- Vaccine Ontology ID: VO_0007099
- Type: Recombinant vector vaccine
- Status: Clinical trial
- Host Species for Licensed Use: Human
- Host Species as Laboratory Animal Model: Human
- Antigen: gp100
- gp100 (PMEL)
gene engineering:
- Type: Recombinant protein preparation
- Description:
- Detailed Gene Information: Click Here.
- Description: This is for Melanoma Cancer (NCT00080353). A viral vaccine comprised of a recombinant fowlpox vector construct encoding a modified epitope of the melanoma antigen glycoprotein 100 (gp100), ES-2092M(gp100), containing an endoplasmic reticulum signal sequence targeted to the endoplasmic reticulum apparatus. Vaccination with recombinant fowlpox-gp100p209 vaccine may stimulate the host immune system more efficiently to mount a cytotoxic T lymphocyte response against tumor cells expressing the gp100 antigen (NCIT_C2806).
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| Host Response |
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| References |
NCIT_C2806: [https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2806]
NCT00080353: [https://clinicaltrials.gov/ct2/show/NCT00080353?term=Recombinant+Fowlpox-gp100p209&rank=1]
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