• Vaccine Name: rPFV-CSFV-E0
• Target Pathogen: Classical swine fever virus
• Target Disease: Classical swine fever, hog cholera
• Vaccine Ontology ID: VO_0004748
• Type: Recombinant vector vaccine
• Status: Research
• Host Species for Licensed Use: Baboon
• Vector:
  • Vector name:
  • VO vector ID: VO_0001040
• Preparation: CSFV E0 gene was amplified from the plasmid pMD18-T-E0 by PCR and cloned into the FPV-P11 and FPV-pSY (Wang et al., 2008).
• Immunization Route: Intramuscular injection (i.m.)

Pig Response

• Vaccination Protocol: Piglets were immunized three times with recombinant Fowlpox virus (Wang et al., 2008).
• Vaccine Immune Response Type: VO_0003057
• Challenge Protocol: The pigs were challenged with CSFV (Wang et al., 2008).
• Efficacy: The protection experiment showed that 75% of piglets immunized three times with recombinant Fowlpox virus were survived, indicating that the recombinant Fowlpox virus was effective (Wang et al., 2008).