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Vaccine Detail

human leukocyte antigen class I-modified peptides
Vaccine Information
  • Vaccine Name: human leukocyte antigen class I-modified peptides
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Vaccine Ontology ID: VO_0007617
  • Type: Peptide vaccine
  • Status: Research
  • Immunization Route: Intramuscular injection (i.m.)
Host Response

Human Response

  • Vaccine Immune Response Type: VO_0003057
  • Immune Response: Vaccination induced a rapid and persistent increase in specific effector memory CD8(+) T cells in 75% of the patients.(Filipazzi et al., 2012)
References
Filipazzi et al., 2012: Filipazzi P, Pilla L, Mariani L, Patuzzo R, Castelli C, Camisaschi C, Maurichi A, Cova A, Rigamonti G, Giardino F, Di Florio A, Asioli M, Frati P, Sovena G, Squarcina P, Maio M, Danielli R, Chiarion-Sileni V, Villa A, Lombardo C, Tragni G, Santinami M, Parmiani G, Rivoltini L. Limited induction of tumor cross-reactive T cells without a measurable clinical benefit in early melanoma patients vaccinated with human leukocyte antigen class I-modified peptides. Clinical cancer research : an official journal of the American Association for Cancer Research. 2012; 18(23); 6485-6496. [PubMed: 23032742].