• Vaccine Name: Chinese S. japonicum DNA vaccine SjCTPI-Hsp70
• Target Pathogen: Schistosoma japonicum
• Target Disease: Schistosomiasis
• Vaccine Ontology ID: VO_0004459
• Type: DNA vaccine
• Status: Research
• Host Species as Laboratory Animal Model: Water buffalo
• TPI gene engineering:
  • Type: DNA vaccine construction
  • Description: This DNA vaccine expressed triose-phosphate isomerase (SjCTPI) fused to bovine heat shock protein 70 (Da'dara et al., 2008).
  • Detailed Gene Information: Click Here.
• DNA vaccine plasmid:
  • DNA vaccine plasmid name:
  • DNA vaccine plasmid VO ID: VO_0000024
• Immunization Route: Intramuscular injection (i.m.)

Water buffalo Response

• Vaccine Immune Response Type: VO_0000286
• Efficacy: This vaccine produced a 51.2% reduction in worm burden, 61.5% liver egg reduction, 52.1% fecal egg reduction and 52.1% reduction in fecal miracidia (Da'dara et al., 2008).