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Vaccine Detail
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Bovine herpesvirus 1 recombinant vector vaccine BHVl/BRSVG |
| Vaccine Information |
- Vaccine Name: Bovine herpesvirus 1 recombinant vector vaccine BHVl/BRSVG
- Target Pathogen: Bovine herpesvirus 1
- Target Disease: Infectious bovine rhinotracheitis
- Vaccine Ontology ID: VO_0004316
- Type: Recombinant vector vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Calves
- G from BRSV
gene engineering:
- Type: Recombinant vector construction
- Description: Vector BHV1 expressed the G protein of bovine respiratory syncytial virus (Schrijver et al., 1997).
- Detailed Gene Information: Click Here.
- Immunization Route: intranasal immunization
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| Host Response |
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Cattle Response
- Vaccine Immune Response Type: VO_0000286
- Efficacy: A gE-negative bovine herpesvirus 1 (BHV1) vector vaccine carrying a gene coding for the G protein of bovine respiratory syncytial virus (BRSV) (BHV1/BRSV-G) induced the same high degree of protection in calves against BRSV infection and BHV1 infection as a multivalent commercial vaccine (Schrijver et al., 1997).
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| References |
Schrijver et al., 1997: Schrijver RS, Langedijk JP, Keil GM, Middel WG, Maris-Veldhuis M, Van Oirschot JT, Rijsewijk FA. Immunization of cattle with a BHV1 vector vaccine or a DNA vaccine both coding for the G protein of BRSV. Vaccine. 1997; 15(17-18); 1908-1916. [PubMed: 9413101].
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