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Vaccine Detail
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Bovine herpesvirus 1 UL23 mutant vaccine |
| Vaccine Information |
- Vaccine Name: Bovine herpesvirus 1 UL23 mutant vaccine
- Target Pathogen: Bovine herpesvirus 1
- Target Disease: Infectious bovine rhinotracheitis
- Product Name: B8-D53
- Vaccine Ontology ID: VO_0002949
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Cow
- UL23
gene engineering:
- Type: Gene mutation
- Description: This UL23 mutant is from Bovine herpesvirus 1 (Kit et al., 1985).
- Detailed Gene Information: Click Here.
- Immunization Route: intranasal immunization
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| Host Response |
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Cattle Response
- Persistence: A UL23 mutant is attenuated in calves (Kit et al., 1985).
- Efficacy: A UL23 mutant induced protection in calves from challenge with wild type BHV-1 (Kit et al., 1985).
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| References |
Kit et al., 1985: Kit S, Qavi H, Gaines JD, Billingsley P, McConnell S. Thymidine kinase-negative bovine herpesvirus type 1 mutant is stable and highly attenuated in calves. Archives of virology. 1985; 86(1-2); 63-83. [PubMed: 2994602].
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