VIOLIN Logo
VO Banner
Search: for Help
About
Introduction
Statistics
VIOLIN News
Your VIOLIN
Register or Login
Submission
Tutorial
Vaccine & Components
Vaxquery
Vaxgen
VBLAST
Protegen
VirmugenDB
DNAVaxDB
CanVaxKB
Vaxjo
Vaxvec
Vevax
Huvax
Cov19VaxKB
Host Responses
VaximmutorDB
VIGET
Vaxafe
Vaxar
Vaxism
Vaccine Literature
VO-SciMiner
Litesearch
Vaxmesh
Vaxlert
Vaccine Design
Vaxign2
Vaxign
Community Efforts
Vaccine Ontology
ICoVax 2012
ICoVax 2013
Advisory Committee
Vaccine Society
Vaxperts
VaxPub
VaxCom
VaxLaw
VaxMedia
VaxMeet
VaxFund
VaxCareer
Data Exchange
V-Utilities
VIOLINML
Help & Documents
Publications
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UM Logo

Vaccine Detail

Classical swine fever virus E(rns) mutant vaccine
Vaccine Information
  • Vaccine Name: Classical swine fever virus E(rns) mutant vaccine
  • Target Pathogen: Classical swine fever virus
  • Target Disease: Classical swine fever, hog cholera
  • Vaccine Ontology ID: VO_0002952
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Pig
  • E(rns) gene engineering:
    • Type: Gene mutation
    • Description: This E(rns) mutant is from Classical swine fever virus (Sainz et al., 2008).
    • Detailed Gene Information: Click Here.
  • Immunization Route: intranasal immunization
Host Response

Pig Response

  • Persistence: An E(rns) mutant is attenuated in swine (Sainz et al., 2008).
  • Efficacy: An E(rns) mutant induces protection in swine from challenge with wild type CSVF (Sainz et al., 2008).
References
Sainz et al., 2008: Sainz IF, Holinka LG, Lu Z, Risatti GR, Borca MV. Removal of a N-linked glycosylation site of classical swine fever virus strain Brescia Erns glycoprotein affects virulence in swine. Virology. 2008; 370(1); 122-129. [PubMed: 17904607].