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Vaccine Detail

Inactivated HIV-2 Vaccine with PMMA
Vaccine Information
  • Vaccine Name: Inactivated HIV-2 Vaccine with PMMA
  • Target Pathogen: Human Immunodeficiency Virus
  • Target Disease: Acquired Immunodeficiency Syndrome (AIDS)
  • Vaccine Ontology ID: VO_0004242
  • Type: Inactivated or "killed" vaccine
  • Status: Research
  • Adjuvant:
  • Immunization Route: subcutaneous injection
Host Response

Mouse Response

  • Host Strain: NMRI
  • Vaccination Protocol: Mice received 0.5 ml of the specified vaccine preparations subcutaneously under the abdominal skin on day 0 (Stieneker et al., 1991).
  • Immune Response: Mice immunized with PMMA adjuvant had higher antibody counts than mice immunized with an alum adjuvant (Stieneker et al., 1991).
References
Stieneker et al., 1991: Stieneker F, Kreuter J, Löwer J. High antibody titres in mice with polymethylmethacrylate nanoparticles as adjuvant for HIV vaccines. AIDS (London, England). 1991; 5(4); 431-435. [PubMed: 2059385].