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Vaccine Detail

Synthetic OMP1 Vaccine
Vaccine Information
  • Vaccine Name: Synthetic OMP1 Vaccine
  • Target Pathogen: Chlamydia trachomatis
  • Target Disease: Chlamydia
  • Vaccine Ontology ID: VO_0004240
  • Type: Subunit vaccine
  • Status: Research
  • Antigen: Lipidic amino acid-based synthetic peptides derived from the variable domains (VD) of Chlamydia trachomatis outer membrane protein 1 (Zhong et al., 1993).
  • Adjuvant:
  • Immunization Route: subcutaneous injection
Host Response

Mouse Response

  • Vaccination Protocol: 50 μg of peptide was injected subcutaneously with NAGO in PBS into the tail base, and was repeated at 14 day intervals (Zhong et al., 1993).
  • Immune Response: NAGO elicited an antibody response similar to that in mice immunized with CFA (Zhong et al., 1993).
References
Zhong et al., 1993: Zhong G, Toth I, Reid R, Brunham RC. Immunogenicity evaluation of a lipidic amino acid-based synthetic peptide vaccine for Chlamydia trachomatis. Journal of immunology (Baltimore, Md. : 1950). 1993; 151(7); 3728-3736. [PubMed: 7690812].