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Vaccine Detail

gp120 recominant with GMDP adjuvant
Vaccine Information
  • Vaccine Name: gp120 recominant with GMDP adjuvant
  • Target Pathogen: Human Immunodeficiency Virus
  • Target Disease: Acquired Immunodeficiency Syndrome (AIDS)
  • Vaccine Ontology ID: VO_0004233
  • Type: Subunit vaccine
  • Status: Research
  • Antigen: Recombinant HIV gp120 derived from CHO cells (Bomford et al., 1992).
  • Adjuvant:
  • Immunization Route: subcutaneous injection
Host Response

Mouse Response

  • Host Strain: BALB/c
  • Vaccination Protocol: Mice were subcutaneously immunized with antigen and adjuvant (Bomford et al., 1992).
  • Immune Response: Mice immunized with gp120 and GMDP in combination with pluronic emulsion resulted in a secondary antibody response (Bomford et al., 1992).
References
Bomford et al., 1992: Bomford R, Stapleton M, Winsor S, McKnight A, Andronova T. The control of the antibody isotype response to recombinant human immunodeficiency virus gp120 antigen by adjuvants. AIDS research and human retroviruses. 1992; 8(10); 1765-1771. [PubMed: 1457190].