VIOLIN: Vaccine Investigation and Online Information Network

Vaccine Comparison

Feline infectiour peritonitis virus 3abc mutant vaccine	Feline infectious peritonitis virus 7ab mutant vaccine
Vaccine Information	Vaccine Information
Type: Live, attenuated vaccine Status: Research Host Species as Laboratory Animal Model: Cat 3a gene engineering: Type: Gene mutation Description: This 3abc mutant is from Feline infectious peritonitis virus (Haijema et al., 2004). Detailed Gene Information: Click Here. 3b gene engineering: Type: Gene mutation Description: This 3abc mutant is from Feline infectious peritonitis virus (Haijema et al., 2004). Detailed Gene Information: Click Here. 3c gene engineering: Type: Gene mutation Description: This 3abc mutant is from Feline infectious peritonitis virus (Haijema et al., 2004). Detailed Gene Information: Click Here. Immunization Route: Oronasal immunization	Type: Live, attenuated vaccine Status: Research Host Species as Laboratory Animal Model: Cat 7a gene engineering: Type: Gene mutation Description: This 7ab mutant is from Feline infectious peritonitis virus (Haijema et al., 2004). Detailed Gene Information: Click Here. 7b gene engineering: Type: Gene mutation Description: This 7ab mutant is from Feline infectious peritonitis virus (Haijema et al., 2004). Detailed Gene Information: Click Here. Immunization Route: Oronasal immunization
Host Response	Host Response
Cat Response Persistence: A 3abc mutant is attenuated in kittens (Haijema et al., 2004). Efficacy: A 3abc mutant induces protection in kittens from challenge with wild type FIPV (Haijema et al., 2004).	Cat Response Persistence: A 7ab mutant is attenuated in kittens (Haijema et al., 2004). Efficacy: A 7ab mutant induces protection in kittens from challenge with wild type FIPV (Haijema et al., 2004).
References	References
*Haijema et al., 2004:* Haijema BJ, Volders H, Rottier PJ. Live, attenuated coronavirus vaccines through the directed deletion of group-specific genes provide protection against feline infectious peritonitis. Journal of virology. 2004; 78(8); 3863-3871. [PubMed: 15047802].	*Haijema et al., 2004:* Haijema BJ, Volders H, Rottier PJ. Live, attenuated coronavirus vaccines through the directed deletion of group-specific genes provide protection against feline infectious peritonitis. Journal of virology. 2004; 78(8); 3863-3871. [PubMed: 15047802].