Gene ID |
Gene Name |
Sequence Strain (Species/Organism) |
VO ID |
NCBI Gene ID |
NCBI Nucleotide GI |
NCBI Protein GI |
Locus Tag |
Genbank Accession |
Protein Accession |
3D structure: PDB ID |
Other Database IDs |
Protein Name |
Molecule Role |
Vaccines Involving this Gene |
1103
|
AsnC |
Brucella abortus 2308 |
|
3788213
|
|
489054600
|
BAB_RS24000 |
JMRZ01000003 |
WP_002964767 |
|
|
ArsR family transcriptional regulator |
Protective antigen |
Recombinant B. abortus AsnC protein with CFA/IFA adjuvant
|
997
|
asp24 |
|
|
|
2352999
|
2353000
|
|
|
AAB69346.1 |
|
CDD:151121 |
acid shock protein |
Virmugen |
B. abortus and B. melitensis mutants with unmarked deletion of asp24, virB2, or manBA
|
114
|
B. abortus strain 19 L7/L12 |
Strain 19 |
VO_0010928
|
|
|
304271
|
|
L19101 |
|
|
CDD:234671 CDD:100102 |
ribosomal protein L7/L12 |
Protective antigen |
B. abortus subunit vaccine using L7/L12
B. abortus DNA vaccine expressing BCSP31, SOD and L7/L12
B. abortus DNA vaccine pcDNA3.1-p39-L7/L12 encoding p39-L7/L12 fusion protein
|
110
|
B. melitensis M5 P39 |
B. melitensis strain M5 |
VO_0010948
|
|
|
122892474
|
|
EF189139 |
ABM67295 |
|
CDD:224567 CDD:304360 |
immunogenic 39-kDa protein |
Protective antigen |
B. melitensis P39 protein vaccine
|
1644
|
BAB1_0278 |
Brucella melitensis biovar Abortus 2308 |
|
|
|
82615279
|
|
|
|
|
CDD:264424 EnsemblGenomes-Gn:BAB1_0278 EnsemblGenomes-Tr:CAJ10234 InterPro: IPR011681 UniProtKB/TrEMBL: Q2YPC5 |
conserved hypothetical protein |
Protective antigen |
B. abortus DNA vaccine pVF278
|
1676
|
BCSP31 |
Brucella abortus |
|
|
144104
|
144105
|
|
|
AAA22993.1 |
|
CDD:273982 |
cell surface protein |
Protective antigen |
B. abortus DNA vaccine expressing BCSP31, SOD and L7/L12
|
1299
|
bcsp31 from Brucella |
Brucella |
|
|
|
361049819
|
|
|
|
|
CDD:32505 CDD:212369 |
TRAP transporter solute receptor, TAXI family precursor |
Other |
|
681
|
Bfr from B. abortus S19 |
Brucella abortus S19 |
VO_0010907
|
6326162
|
|
189022832
|
BAbS19_II06320 |
CP000888 |
YP_001932573 |
|
|
Bacterioferritin |
Protective antigen |
|
255
|
Bfr from B. melitensis biovar Abortus 2308 |
Brucella abortus 2308 |
VO_0010968
|
3828133
|
|
489055925
|
BAB_RS29555 |
JMRZ01000012 |
WP_002966069 |
3FVB
|
|
bacterioferritin |
Protective antigen |
|
232
|
Bp26 |
Brucella melitensis bv. 1 str. 16M |
VO_0010962
|
1196247
|
|
17986819
|
BMEI0536 |
AE008917 |
NP_539453 |
|
|
immunogenic protein |
Protective antigen |
|
1053
|
bp26 |
Brucella melitensis bv. 1 str. Rev.1 |
|
|
|
265991532
|
|
|
|
|
CDD:194028 |
outer membrane protein Bp26 |
Virmugen |
Brucella melitensis bp26 mutant vaccine
|
1102
|
cobB |
Brucella abortus 2308 |
|
3787893
|
|
489054238
|
BAB_RS22225 |
JMRZ01000005 |
WP_002964414 |
|
|
hydrogenobyrinate a,c-diamide synthase |
Protective antigen |
Recombinant B. abortus CobB protein with CFA/IFA adjuvant
|
1301
|
cp24 from Brucella melitensis |
Brucella melitensis |
|
|
|
1674445
|
|
|
|
|
CDD:178850 CDD:29621 |
CP24 |
Other |
|
257
|
DnaK |
Brucella abortus bv. 1 str. 9-941 |
VO_0010970
|
3341115
|
|
62290965
|
BruAb1_2100 |
AE017223 |
YP_222758 |
|
|
molecular chaperone DnaK |
Protective antigen |
|
934
|
exsA |
Brucella melitensis biovar Abortus 2308 |
|
3787220
|
|
82699354
|
BAB1_0468 |
AM040264 |
YP_413928 |
|
|
ABC transporter ATPase |
Virmugen |
Brucella abortus exsA mutant vaccine
|
823
|
Gap |
Brucella abortus bv. 1 str. 9-941 |
VO_0012375
|
3340207
|
|
62290600
|
BruAb1_1713 |
AE017223 |
YP_222393 |
|
|
glyceraldehyde-3-phosphate dehydrogenase |
Protective antigen |
|
1300
|
groEL from Brucella abortus |
Brucella abortus bv. 1 str. 9-941 |
|
3341925
|
|
62317142
|
BruAb2_0190 |
AE017224 |
YP_222995 |
|
|
molecular chaperone GroEL |
Other |
|
254
|
IalB |
Brucella melitensis bv. 1 str. 16M |
VO_0010967
|
1197295
|
|
17987867
|
BMEI1584 |
AE008917 |
NP_540501 |
|
|
invasion protein B |
Protective antigen |
B. melitensis DNA vaccine p-ialB
|
1677
|
L7/L12 |
Brucella abortus RB51-AHVLA |
|
|
|
479804332
|
|
|
|
|
CDD:100102 |
50S ribosomal protein L7/L12 |
Protective antigen |
Divalent DNA B. abortus Vaccine pcDNA3.1-L7/L12-Omp16
|
1000
|
manA |
Brucella melitensis bv. 1 str. 16M |
|
|
|
260563601
|
BAB1_0562 |
|
|
|
CDD:32765 CDD:29324 |
ManA family protein |
Virmugen |
B. abortus and B. melitensis mutants with unmarked deletion of asp24, virB2, or manBA
|
999
|
manB |
Brucella melitensis bv. 1 str. 16M |
|
1198671
|
|
17989244
|
BMEII0899 |
AE008918 |
NP_541877 |
|
|
phosphomannomutase |
Virmugen |
B. abortus and B. melitensis mutants with unmarked deletion of asp24, virB2, or manBA
|
1084
|
mucR |
Brucella melitensis bv. 1 str. 16M |
|
1197075
|
|
17987647
|
BMEI1364 |
AE008917 |
NP_540281 |
|
|
transcriptional regulatory protein MUCR |
Virmugen |
Brucella melitensis mucR mutant vaccine
|
260
|
Omp16 |
Brucella abortus 2308 |
VO_0010973
|
3788229
|
|
489056820
|
BAB_RS24085 |
AM040264 |
WP_002966947 |
|
|
hypothetical protein |
Protective antigen |
B. abortus DNA vaccine encoding RplL and Omp16
|
1678
|
omp16 |
Brucella abortus RB51-AHVLA |
|
|
|
479804733
|
|
|
|
|
CDD:225439 CDD:143586 |
outer membrane lipoprotein omp16 |
Protective antigen |
Divalent DNA B. abortus Vaccine pcDNA3.1-L7/L12-Omp16
|
259
|
Omp19 |
Brucella abortus 2308 |
VO_0010972
|
3788831
|
|
489054833
|
BAB_RS25135 |
AM040264 |
WP_002964998 |
|
|
hypothetical protein |
Protective antigen |
|
253
|
Omp25 |
Brucella melitensis bv. 1 str. 16M |
VO_0010966
|
1196960
|
|
17987532
|
BMEI1249 |
AE008917 |
NP_540166 |
|
|
hypothetical protein |
Protective antigen |
Brucella melitensis omp25 mutant vaccine
B. melitensis DNA vaccine p-Omp25
|
231
|
Omp31 |
Brucella abortus 2308 |
VO_0010939
|
3788834
|
|
489054549
|
BAB_RS23735 |
AM040264 |
WP_002964719 |
|
|
membrane protein |
Protective antigen |
B. melitensis 16M DNA vaccine expressing Omp31
|
1054
|
omp31 |
Brucella melitensis ATCC 23457 |
|
7676420
|
|
225853091
|
BMEA_A1674 |
CP001488 |
YP_002733324 |
|
|
outer membrane protein Omp31 |
Virmugen |
B. melitensis DNA vaccine encoding Omp31 boosted with Omp31
Brucella melitensis omp31 mutant vaccine
|
1609
|
omp31 |
Brucella melitensis bv. 1 str. 16M |
|
|
|
61229373
|
|
|
|
|
CDD:226163 |
31 kDa outer-membrane immunogenic protein |
Protective antigen |
B. melitensis DNA vaccine pCI-Omp31
B. melitensis DNA vaccine pCIBLSOmp31 encoding BLSOmp31 (fusion protein)
|
113
|
ORF |
|
VO_0010927
|
|
599653
|
599654
|
|
|
CAA86936.1 |
1DI0
|
CDD:237096 CDD:187741 GOA:P61711 InterPro: IPR002180 PDB: 1DI0 PDB: 1T13 PDB: 1XN1 UniProtKB/UniProt: P61711 |
|
Protective antigen |
B. abortus pcDNA-BLS
B. melitensis DNA vaccine pCIBLSOmp31 encoding BLSOmp31 (fusion protein)
|
1358
|
P39 from Brucella abortus |
Brucella abortus bv. 1 str. 9-941 |
|
|
|
68067499
|
|
|
|
|
CDD:224567 |
Probable sugar-binding periplasmic protein |
Protective antigen |
B. abortus DNA vaccine pcI-p39 encoding P39 (periplasmic-binding protein)
B. abortus DNA vaccine pcDNA3.1-p39-L7/L12 encoding p39-L7/L12 fusion protein
|
3898
|
PALFn |
Bacillus anthracis |
|
|
|
AKB95640
|
|
|
|
|
CDD:284994 CDD:281492 CDD:285037 CDD:286266 CDD:238144 |
PALFn |
Protective antigen |
|
955
|
pgk |
Brucella melitensis biovar Abortus 2308 |
|
3788256
|
|
82700518
|
BAB1_1742 |
AM040264 |
YP_415092 |
|
|
phosphoglycerate kinase |
Virmugen |
Brucella abortus pgk mutant vaccine
|
978
|
pgm |
Brucella melitensis biovar Abortus 2308 |
|
3788847
|
|
82698981
|
BAB1_0055 |
AM040264 |
YP_413555 |
|
|
phosphoglucomutase |
Virmugen |
Brucella abortus pgm mutant vaccine
|
939
|
purE |
Brucella melitensis bv. 1 str. 16M |
|
|
|
600729
|
BMEI0295 |
NZ_GG703781 |
NP_539212 |
|
CDD:200634 |
5'-phosphoribosyl-5-amino-4-imidazole carboxylase |
Virmugen |
B. melitensis WR201 (16MΔpurEK)
|
239
|
purK |
Brucella melitensis bv. 1 str. 16M |
|
|
|
20141763
|
|
|
|
|
CDD:180352 CDD:200773 CDD:194530 |
N5-carboxyaminoimidazole ribonucleotide synthase |
Virmugen |
B. melitensis WR201 (16MΔpurEK)
|
237
|
RL3382 |
Rhizobium leguminosarum bv. viciae 3841 |
|
4399754
|
|
116253124
|
RL3382 |
NC_008380 |
YP_768962 |
|
|
putative outer membrane protein related to bp26 antigen of Brucella |
|
B. melitensis with deleted bp26 (CGV26)
|
682
|
RplL |
Brucella abortus 2308 |
VO_0010908
|
3788918
|
|
489054195
|
BAB_RS21965 |
AM040264 |
WP_002964371 |
|
|
50S ribosomal protein L7/L12 |
Protective antigen |
B. abortus DNA vaccine encoding RplL and Omp16
|
236
|
RpsL |
Brucella melitensis bv. 1 str. 16M |
VO_0010963
|
1196463
|
|
161511151
|
BMEI0752 |
NZ_GG703780 |
NP_539669 |
|
|
30S ribosomal protein S12 |
Other |
B. melitensis vaccine strain Rev. 1
|
919
|
sadfasfd |
|
|
|
|
|
|
|
|
|
|
|
|
|
3
|
SodC from B. abortus strain 2308 |
Brucella abortus 2308 |
VO_0010856
|
3827840
|
|
489062065
|
BAB_RS28905 |
AM040265 |
WP_002972093 |
2AQM
|
|
superoxide dismutase [Cu-Zn] |
Protective antigen |
Recombinant B. abortus RB51SOD
B. abortus DNA vaccine pcDNA-SOD
B. abortus DNA vaccine expressing BCSP31, SOD and L7/L12
B. abortus DNA vaccine pcDNA3-SOD encoding Cu-Zn SOD
|
258
|
SurA |
Brucella abortus 2308 |
VO_0010971
|
3787419
|
|
489056605
|
BAB_RS19295 |
JMRZ01000012 |
WP_002966738 |
|
|
molecular chaperone SurA |
Protective antigen |
Brucella recombinant SurA protein vaccine
|
4390
|
surA test |
|
|
|
|
|
|
|
|
|
|
|
|
|
256
|
Tig |
Brucella melitensis bv. 1 str. 16M |
VO_0010969
|
1196780
|
|
17987352
|
BMEI1069 |
AE008917 |
NP_539986 |
|
|
trigger factor |
Protective antigen |
B. melitensis bp26 and TF Nasal Vaccine
|
998
|
virB2 |
Brucella melitensis biovar Abortus 2308 |
|
3827981
|
|
83269021
|
BAB2_0067 |
AM040265 |
YP_418312 |
|
|
type IV secretion system protein VirB2 |
Virmugen |
B. abortus and B. melitensis mutants with unmarked deletion of asp24, virB2, or manBA
|
233
|
VjbR |
Brucella melitensis 16M |
|
1198888
|
|
17989461
|
BMEII1116 |
NC_003318 |
NP_542094 |
|
|
TRANSCRIPTIONAL ACTIVATOR, LUXR FAMILY |
Virmugen |
Microencapsulated B. melitensis vjbR mutant vaccine
|
1208
|
vjbR |
Brucella abortus S19 |
|
6326704
|
|
189022339
|
BAbS19_II01090 |
CP000888 |
YP_001932080 |
|
|
LuxR family regulatory protein; VjbR |
Virmugen |
Brucella abortus S19 vjbR mutant vaccine
|
228
|
znuA |
Brucella melitensis biovar Abortus 2308 |
VO_0012365
|
3827700
|
|
83269918
|
BAB2_1079 |
AM040265 |
YP_419209 |
|
|
periplasmic solute binding protein |
Virmugen |
Live attenuated B. abortus with deletion of znuA
|