• Vaccine Name: FluMist
• Target Pathogen: Influenza virus
• Target Disease: Influenza (flu)
• Product Name: Influenza Virus Vaccine Live, Intranasal
• Tradename: FluMist
• Manufacturer: AstraZeneca
• Vaccine Ontology ID: VO_0000044
• CDC CVX code: 111
• Type: Live, attenuated vaccine
• Status: Licensed
• Location Licensed: USA (License #1652), Canada
• Host Species for Licensed Use: Human
• Antigen: influenza virus subtypes A and type B. Flumist contains three strains: A/South Dakota/6/2007 (H1N1) (A/Brisbane/59/2007-like), A/Uruguay/716/2007 (H3N2) (A/Brisbane/10/2007-like), and B/Florida/4/2006 (FDA: Flumist).
• Allergen: Eggs, Arginine, Gelatin, Gentamicin
• Preparation: Eggs are inoculated with each of the strains and incubated. The fluid of these eggs is harvested, pooled and then filtrated. The virus is ultracentrifugated and diluted with stabilizing buffer. Ethylene diamine tetracetic acid (EDTA) is added to the dilution buffer for H3N2 strains. The viral harvests are then sterile filtered to produce the monovalent bulks. Each lot is tested for ca, ts, and att phenotypes and is also tested extensively by in vitro and in vivo methods to detect adventitious agents. Monovalent bulks from the three strains are subsequently blended and diluted as required to attain the desired potency with stabilizing buffers to produce the trivalent bulk vaccine. The bulk vaccine is then filled directly into individual sprayers for nasal administration (FDA: Flumist).
• Immunization Route: Nasal spray
• Storage: FluMist is supplied for intranasal delivery in a package of 10 pre-filled, single-use sprayers. It should be stored in a refrigerator between 2-8°C (35-46°F).
• Approved Age for Licensed Use: Ages 2-49(FluMist website)
• Contraindication: FLUMIST should not be administered to anyone with a known history of hypersensitivity, especially anaphylactic reactions, to eggs, egg proteins, gentamicin, gelatin, or arginine or with life-threatening reactions to previous influenza vaccinations. FLUMIST also is contraindicated in children and adolescents (2-17 years of age) receiving aspirin therapy or aspirin-containing therapy, because of the association of Reye’s syndrome with aspirin and wild-type influenza infection (FDA: Flumist).
  
  FLUMIST should also not be administered to anyone with asthma. FLUMIST should not be given to children who use a bronchodilator or steroids.
• Description: This vaccine should be used for the active immunization of individuals 2-49 years of age against influenza disease.

Human Response

• Vaccination Protocol: A multinational, randomized, double-blind, active-controlled trial (MI-CP111) was performed to assess the efficacy and safety of FLUMIST compared to an injectable influenza vaccine in children <5 years of age, using the refrigerated formulation.
• Side Effects: Side effects found in children included: fever, cough, sore throat, or runny nose/nasal congestion.
• Efficacy: In the primary efficacy analysis, FLUMIST demonstrated a 44.5% (95% CI: 22.4, 60.6) reduction in influenza rate compared to active control as measured by culture-confirmed modified CDC-ILI caused by wild-type strains antigenically similar to those contained in the vaccine (FDA: Flumist).

Human Response

• Immune Response: FluMist is not indicated in children <24 months of age. In a clinical trial, among children 6-23 months of age, wheezing requiring bronchodilator therapy or with significant respiratory symptoms occurred in 5.9% of FluMist recipients compared to 3.8% of active control (injectable influenza vaccine made by Sanofi Pasteur Inc.) recipients (Relative Risk 1.5, 95% CI: 1.2, 2.1). Wheezing was not increased in children ≥24 months of age. (FDA: Flumist)
• Immune Response Assay Type: HI antibody assay
• Side Effects: Side effects found in children included: fever, cough, sore throat, or runny nose/nasal congestion
• Efficacy: A randomized, double-blind, placebo-controlled trial (D153-P501) was performed to evaluate the efficacy of FLUMIST in children 12 to 35 months of age using the refrigerated formulation (FDA: Flumist).

Human Response

• Vaccination Protocol: AV006 was a multi-center, randomized, double-blind, placebo-controlled trial performed in U.S. children without high-risk medical conditions to evaluate the efficacy of FLUMIST against culture-confirmed influenza over two successive seasons using the frozen formulation (FDA: Flumist).
• Side Effects: Side effects found in children included: fever, cough, sore throat, or runny nose/nasal congestion
• Efficacy: FLUMIST demonstrated 87.0% efficacy against culture-confirmed influenza illness (FDA: Flumist).

Human Response

• Vaccination Protocol: AV009 was a multi-center, randomized, double-blind, placebo-controlled trial of FLUMIST to evaluate effectiveness in adults 18-64 years of age without high-risk medical conditions.
• Side Effects: Side effects of this study include: runny nose, headache, sore throat, tiredness/weakness, muscle aches, cough, and chills

Human Response

• Vaccination Protocol: In this study the safety and shedding of vaccine virus following FLUMIST administration was evaluated in 57 HIV-infected and 54 HIV-negative adults 18-58 years of age. The study was a randomized, double-blind, placebo controlled trial using the frozen formulation
• Side Effects: No serious adverse events were reported during the one-month follow-up period and no adverse effects on HIV viral load or CD4 counts were identified following FLUMIST administration (FDA: Flumist).
• Description: The effectiveness of FLUMIST in preventing influenza illness in HIV-infected individuals has not been evaluated

Human Response

• Vaccination Protocol: A single open-label dose of trivalent LAIV was administered intranasally to 344 subjects in 3 age cohorts: 5–8, 9–17, and 18–49 years of age. Shedding was determined by culture of nasal swabs (on days 1–7, daily; days 9–25, every other day; and day 28). Immunogenicity was measured as serum strain-specific hemagglutinin inhibition (HAI) titers (days 0, 28) (Block et al., 2008).
• Immune Response: Among subjects aged 5–8 years, 9–17 years, and 18–49 years, 44%, 27%, and 17% of subjects, respectively, shed vaccine virus after vaccination. Shedding incidence was inversely correlated to age and baseline serum HAI antibody titer. The seroresponse rate (4-fold rise in HAI antibody titers) to at least one strain was 59% (68%, 64%, and 47%, respectively, by age group). Strain-specific rates were higher in baseline seronegative and serosusceptible subjects (Block et al., 2008).
• Immune Response Assay Type: HI antibody assay
• Side Effects: Reactogenicity, most commonly runny nose, headache, and sore throat, was not associated with shedding or seroresponse (Block et al., 2008).

Human Response

• Vaccination Protocol: FluMist was used to vaccinate human subjects. Peripheral blood mononuclear cells (PBMCs) were collected from all 56 vaccinees on days 0, 3, and 7 after vaccination. Microarray experiment was then performed using the PBMC samples.
• Vaccine Immune Response Type: VO_0000286
• Host APOBEC3G response
  • Description: APOBEC3G, a gene closely associated with interferon signal pathways, was up-regulated on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host C3AR1 response
  • Description: C3AR1, a gene closely associated with interferon signal pathways, was up-regulated on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CASP1 response
  • Description: CASP1, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CD14 response
  • Description: CD14, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CD244 response
  • Description: CD244, a gene closely associated with interferon signal pathways, was up-regulated on Day 7 but not on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CIITA response
  • Description: CIITA, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 but not on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CSF1R from humans response
  • Description: CSF1R, a gene closely associated with interferon signal pathways, was up-regulated on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CXCL1 response
  • Description: CXCL1, a gene closely associated with interferon signal pathways, was down-regulated on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011)
  • Detailed Gene Information: Click Here.
• Host EIF2S1 response
  • Description: EIF2S1, a gene closely associated with interferon signal pathways, was up-regulated on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host human STAT1 response
  • Description: STAT1, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 but not on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ICAM1 response
  • Description: ICAM1, a gene closely associated with interferon signal pathways, was down-regulated on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ICAM2 response
  • Description: ICAM2, a gene closely associated with interferon signal pathways, was up-regulated on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IFI16 response
  • Description: IFI16, a gene closely associated with interferon signal pathways, was up-regulated on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IFI35 response
  • Description: IFI35, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 but not on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IL6R response
  • Description: IL6R, a gene closely associated with interferon signal pathways, was up-regulated on Day 7 but not on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IL8 response
  • Description: IL8, a gene closely associated with interferon signal pathways, was down-regulated on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IRAK3 response
  • Description: IRAK3, a gene closely associated with interferon signal pathways, was up-regulated on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IRF5 response
  • Description: IRF5, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host JUN response
  • Description: JUN, a gene closely associated with interferon signal pathways, was up-regulated on Day 7 but not on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MAVS response
  • Description: MAVS, a gene closely associated with interferon signal pathways, was up-regulated on Day 7 but not on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MX1 response
  • Description: MX1, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 but not on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MX2 response
  • Description: MX2, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 but not on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host OAS1 response
  • Description: OAS1, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host OAS1 response
  • Description: OAS1, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host OAS2 response
  • Description: OAS2, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host OAS3 response
  • Description: OAS3, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 but not on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host OSM response
  • Description: OSM, a gene closely associated with interferon signal pathways, was down-regulated on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PLSCR1 response
  • Description: PLSCR1, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 but not on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SOCS3 response
  • Description: SOCS3, a gene closely associated with interferon signal pathways, was down-regulated on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host STAT2 response
  • Description: STAT2, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 but not on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TICAM2 response
  • Description: TICAM2, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TLR7 response
  • Description: TLR7, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 but not on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TLR8 response
  • Description: TLR8, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TNFSF10 response
  • Description: TNFSF10, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TNFSF13 response
  • Description: TNFSF13, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TNFSF13B response
  • Description: TNFSF13B, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 but not on Day 7 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host XAF1 response
  • Description: XAF1, a gene closely associated with interferon signal pathways, was up-regulated on Day 3 after FluMist vaccination. The expression of this gene was not altered by the vaccination of trivalent inactivated influenza vaccine (TIV) (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.

Human Response

• Vaccination Protocol: FluMist was used to vaccinate human subjects. Peripheral blood mononuclear cells (PBMCs) were collected from all 56 vaccinees on days 0 (basic line) and 7 after vaccination. The PBMCs were used to sort out specific cell types, including myeloid dendritic cells (mDCs), plasmacytoid dendritic cells (pDCs), monocytes, and B cells. Microarray experiments were then performed using the samples of whole PBMCs and specific cell types (Nakaya et al., 2011).
• Vaccine Immune Response Type: VO_0000286
• Host ABCB1 response
  • Description: Compared to Day 0 (baseline), ABCB1 was up-regulated in pDCs and B-cells post vaccination with FluMist. No change in ABCB1 expression was observed in PMBCs, mononcytes, or mDCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011)
  • Detailed Gene Information: Click Here.
• Host ALCAM response
  • Description: Compared to Day 0 (baseline), ALCAM was up-regulated in pDCs post vaccination with FluMist. No change in ALCAM expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ANXA2 response
  • Description: Compared to Day 0 (base line), ANXA2 was up-regulated in PMBCs and pDCs at Day 7 post vaccination with FluMist. No change in ANXA2 expression was observed in monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host APOBEC3F response
  • Description: Compared to Day 0 (base line), APOBEC3F was up-regulated in PMBCs but was down-regulated in the mDCs at Day 7 post vaccination with FluMist. No change in APOBEC3F expression was observed in monocytes, pDCs, or B cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host APOBEC3G response
  • Description: Compared to Day 0 (base line), APOBEC3G was up-regulated in PMBCs and pDCs at Day 7 post vaccination with FluMist. No change in APOBEC3G expression was observed in monocytes, mDCs, or B cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host C1QBP response
  • Description: Compared to Day 0 (baseline), C1QBP was up-regulated in pDCs post vaccination with FluMist. No change in C1QBP expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host C5AR1 response
  • Description: Compared to Day 0 (baseline), C5AR1 was down-regulated in PMBCs but up-regulated in monocytes at Day 7 post vaccination with FluMist. No change in C5AR1 expression was observed in mDCs, pDCs or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CCL3 response
  • Description: Compared to Day 0 (baseline), CCL3 was up-regulated in monocytes post vaccination with FluMist. No change in CCL3 expression was observed in PMBCs, monocytes, mDCs, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CCL4 response
  • Description: Compared to Day 0 (baseline), CCL4 was up-regulated in monocytes post vaccination with FluMist. No change in CCL4 expression was observed in PMBCs, monocytes, mDCs, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CCND3 response
  • Description: Compared to Day 0 (baseline), CCND3 was up-regulated in monocytes, mDCs, pDCs, and B-cells post vaccination with FluMist. No change in CCND3 expression was observed in PMBCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CCND3 response
  • Description: Compared to Day 0 (baseline), CCND3 was up-regulated in monocytes, mDCs, pDCs, and B-cells post vaccination with FluMist. No change in CCND3 expression was observed in PMBCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CCND3 response
  • Description: Compared to Day 0 (baseline), CCND3 was up-regulated in monocytes, mDCs, pDCs, and B-cells post vaccination with FluMist. No change in CCND3 expression was observed in PMBCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CCR1 response
  • Description: Compared to Day 0 (baseline), CCR1 was up-regulated in pDCs post vaccination with FluMist. No change in CCR1 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CCR2 response
  • Description: Compared to Day 0 (baseline), CCR2 was up-regulated in PMBCs, monocytes and pDCs post vaccination with FluMist. No change in CCR2 expression was observed in mDCs or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CD55 response
  • Description: Compared to Day 0 (baseline), CD55 was down-regulated in PMBCs but up-regulated in pDCs at Day 7 post vaccination with FluMist. No change in CD55 expression was observed in monocytes, mDCs or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CD86 response
  • Description: Compared to Day 0 (baseline), CD86 was up-regulated in PMBCs and monocytes post vaccination with FluMist. No change in CD86 expression was observed in mDCs, pDCs or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CIITA response
  • Description: Compared to Day 0 (base line), CIITA was up-regulated in PMBCs and monocytes post vaccination with FluMist. No change in CIITA expression was observed in mDCs or pDCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CRK response
  • Description: Compared to Day 0 (baseline), CRK was up-regulated in mDCs post vaccination with FluMist. No change in CRK expression was observed in PMBCs, monocytes, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CSF2RA response
  • Description: Compared to Day 0 (baseline), CSF2RA was up-regulated in PMBCs, mDCs, and pDCs post vaccination with FluMist. No change in CSF2RA expression was observed in B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CSF3 response
  • Description: Compared to Day 0 (baseline), CSF3 was down-regulated in pDCs post vaccination with FluMist. No change in CSF3 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CX3CR1 response
  • Description: Compared to Day 0 (base line), CX3CR1 was up-regulated in PMBCs and monocytes post vaccination with FluMist. No change in CX3CR1 expression was observed in mDCs, pDCs or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CXCL1 response
  • Description: Compared to Day 0 (baseline), CXCL1 was down-regulated in PMBCs but up-regulated in monocytes at Day 7 post vaccination with FluMist. No change in CXCL1 expression was observed in mDCs or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host DAPK1 response
  • Description: Compared to Day 0 (base line), DAPK1 was up-regulated in PMBCs and pDCs post vaccination with FluMist. No change in DAPK1 expression was observed in monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host EIF2S1 response
  • Description: Compared to Day 0 (base line), EIF2S1 was up-regulated in PMBCs and pDCs at Day 7 post vaccination with FluMist. No change in EIF2S1 expression was observed in monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ETS2 response
  • Description: Compared to Day 0 (baseline), ETS2 was up-regulated in monocytes and mDCs post vaccination with FluMist. No change in ETS2 expression was observed in PMBCs, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host FLT3 response
  • Description: Compared to Day 0 (base line), FLT3 was up-regulated in PMBCs and pDCs post vaccination with FluMist. No change in FLT3 expression was observed in monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host FOS response
  • Description: Compared to Day 0 (baseline), FOS was up-regulated in mDCs post vaccination with FluMist. No change in FOS expression was observed in PMBCs, monocytes, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host HSPA1A response
  • Description: Compared to Day 0 (baseline), HSPA1A was up-regulated in monocytes post vaccination with FluMist. No change in HSPA1A expression was observed in PMBCs, monocytes, mDCs, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host HSPD1 response
  • Description: Compared to Day 0 (baseline), HSPD1 was up-regulated in pDCs post vaccination with FluMist. No change in HSPD1 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host Human CAMK4 (CaMKIV) response
  • Description: Human CAMK4 is a marker of Flumist-induced protective immunity (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IFNAR1 response
  • Description: Compared to Day 0 (baseline), IFNAR1 was up-regulated in mDCs post vaccination with FluMist. No change in IFNAR1 expression was observed in PMBCs, monocytes, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IFNGR1 response
  • Description: Compared to Day 0 (baseline), IFNGR1 was down-regulated in PMBCs and B-cells but up-regulated in monocytes at Day 7 post vaccination with FluMist. No change in IFNGR1 expression was observed in mDCs or pDCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IFRD1 response
  • Description: Compared to Day 0 (baseline), IFRD1 was down-regulated in PMBCs but up-regulated in monocytes, mDCs, and pDCs at Day 7 post vaccination with FluMist. No change in IFRD1 expression was observed in B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IKBKB response
  • Description: Compared to Day 0 (baseline), IKBKB was up-regulated in PMBC, mDCs, and pDCs post vaccination with FluMist. No change in IKBKB expression was observed in monocytes or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IL10RB response
  • Description: Compared to Day 0 (baseline), IL10RB was up-regulated in PMBCs and monocytes but was down-regulated in B-cells at Day 7 post vaccination with FluMist. No change in IL10RB expression was observed in mDCs or pDCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IL13RA1 response
  • Description: Compared to Day 0 (baseline), IL13RA1 was up-regulated in mDCs and pDCs post vaccination with FluMist. No change in IL13RA1 expression was observed in PMBCs, monocytes, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IL18R1 response
  • Description: Compared to Day 0 (baseline), IL18R1 was up-regulated in mDCs post vaccination with FluMist. No change in IL18R1 expression was observed in PMBCs, monocytes, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IL1B response
  • Description: Compared to Day 0 (baseline), IL1B was down-regulated in PMBCs and pDCs at Day 7 post vaccination with FluMist. No change in IL1B expression was observed in monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IL4R response
  • Description: Compared to Day 0 (baseline), ISG20 was up-regulated in mDCs and pDCs post vaccination with FluMist. No change in ISG20 expression was observed in PMBCs, monocytes, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IL6 response
  • Description: Compared to Day 0 (baseline), IL6 was up-regulated in monocytes but down-regulated in pDCs post vaccination with FluMist. No change in IL6 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IL6R response
  • Description: Compared to Day 0 (baseline), IL6R was up-regulated in pDCs post vaccination with FluMist. No change in IL6R expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IL6ST response
  • Description: Compared to Day 0 (baseline), IL6ST was down-regulated in B-cells post vaccination with FluMist. No change in IL6ST expression was observed in PMBCs, monocytes, or mDCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IL8 response
  • Description: Compared to Day 0 (baseline), IL8 was down-regulated in PMBCs but up-regulated in monocytes at Day 7 post vaccination with FluMist. No change in IL8 expression was observed in mDCs, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IRAK1 response
  • Description: Compared to Day 0 (baseline), IRAK1 was up-regulated in monocytes post vaccination with FluMist. No change in IRAK1 expression was observed in PMBCs, monocytes, mDCs, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IRF2 response
  • Description: Compared to Day 0 (baseline), IRF2 was up-regulated in pDCs post vaccination with FluMist. No change in IRF2 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IRF7 response
  • Description: Compared to Day 0 (base line), IRF7 was down-regulated in monocytes at Day 7 post vaccination with FluMist. No change in IRF7 expression was observed in mDCs, pDCs, or B cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ISG20 response
  • Description: Compared to Day 0 (baseline), ISG20 was up-regulated in pDCs post vaccination with FluMist. No change in ISG20 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ITGA4 response
  • Description: Compared to Day 0 (baseline), ITGA4 was up-regulated in pDCs post vaccination with FluMist. No change in ITGA4 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IVNS1ABP response
  • Description: Compared to Day 0 (baseline), IVNS1ABP was up-regulated in mDCs post vaccination with FluMist. No change in IVNS1ABP expression was observed in PMBCs, monocytes, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host JAK2 response
  • Description: Compared to Day 0 (baseline), JAK2 was up-regulated in pDCs post vaccination with FluMist. No change in JAK2 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host JUN response
  • Description: Compared to Day 0 (base line), JUN was up-regulated in PMBCs, monocytes, and B-cells post vaccination with FluMist. No change in JUN expression was observed in mDCs, or pDCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host KRAS response
  • Description: Compared to Day 0 (baseline), KRAS was down-regulated in PMBCs and mDCs at Day 7 post vaccination with FluMist. No change in KRAS expression was observed in monocytes, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MAP3K14 response
  • Description: Compared to Day 0 (baseline), MAP3K14 was up-regulated in monocytes post vaccination with FluMist. No change in MAP3K14 expression was observed in PMBCs, mDCs, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MAP3K5 response
  • Description: Compared to Day 0 (baseline), MAP3K5 was up-regulated in pDCs post vaccination with FluMist. No change in MAP3K5 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MAP3K7 response
  • Description: Compared to Day 0 (baseline), MAP3K7 was up-regulated in pDCs post vaccination with FluMist. No change in MAP3K7 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MAPK1 response
  • Description: Compared to Day 0 (base line), MAPK1 was up-regulated in PMBCs, mDCs, and pDCs post vaccination with FluMist. No change in MAPK1 expression was observed in monocytes or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MAPK14 response
  • Description: Compared to Day 0 (baseline), MAPK14 was up-regulated in pDCs post vaccination with FluMist. No change in MAPK14 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MAPKAPK2 response
  • Description: Compared to Day 0 (baseline), MAPKAPK2 was down-regulated in PMBCs and monocytes at Day 7 post vaccination with FluMist. No change in MAPKAPK2 expression was observed in mDCs, pDCs, or B cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MNDA response
  • Description: Compared to Day 0 (base line), MNDA was up-regulated in PMBCs and monocytes but was down-regulated in the B-cells at Day 7 post vaccination with FluMist. No change in MNDA expression was observed in mDCs or pDCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MSR1 response
  • Description: Compared to Day 0 (baseline), MSR1 was up-regulated in mDCs post vaccination with FluMist. No change in MSR1 expression was observed in PMBCs, monocytes, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host OAS1 response
  • Description: Compared to Day 0 (base line), OAS1 was up-regulated in PMBCs and pDCs post vaccination with FluMist. No change in OAS1 expression was observed in monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMis (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PIK3C3 response
  • Description: Compared to Day 0 (base line), PIK3C3 was down-regulated in the mDCs cells but was up-regulated in B-cells at Day 7 post vaccination with FluMist. No change in PIK3C3 expression was observed in monocytes or pDCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PIK3CA response
  • Description: Compared to Day 0 (baseline), PIK3CA was down-regulated in PMBCs and mDCs but up-regulated in pDCs at Day 7 post vaccination with FluMist. No change in PIK3CA expression was observed in monocytes or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PIK3CG response
  • Description: Compared to Day 0 (baseline), PIK3CG was down-regulated in monocytes post vaccination with FluMist. No change in PIK3CG expression was observed in PMBCs, mDCs, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PRKCA from humans response
  • Description: Compared to Day 0 (baseline), PRKCA was up-regulated in mDCs and pDCs post vaccination with FluMist. No change in PRKCA expression was observed in PMBCs, monocytes, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PTGS2 response
  • Description: Compared to Day 0 (baseline), PTGS2 was down-regulated in PMBCs but up-regulated in monocytes and mDCs at Day 7 post vaccination with FluMist. No change in PTGS2 expression was observed in B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host REL response
  • Description: Compared to Day 0 (baseline), REL was down-regulated in PMBCs and monocytes at Day 7 post vaccination with FluMist. No change in REL expression was observed in mDCs, pDCs, or B cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SIRPA response
  • Description: Compared to Day 0 (baseline), SIRPA was down-regulated in monocytes post vaccination with FluMist. No change in SIRPA expression was observed in PMBCs, mDCs, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SOCS3 response
  • Description: Compared to Day 0 (baseline), SOCS3 was down-regulated in PMBCs and monocytes but up-regulated in mDCs at Day 7 post vaccination with FluMist. No change in SOCS3 expression was observed in pDCs or B cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host STAT6 response
  • Description: Compared to Day 0 (baseline), STAT6 was up-regulated in pDCs post vaccination with FluMist. No change in STAT6 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TCF7L2 response
  • Description: Compared to Day 0 (baseline), TCF7L2 was up-regulated in pDCs post vaccination with FluMist. No change in TCF7L2 expression was observed in PMBCs, monocytes, mDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TFRC response
  • Description: Compared to Day 0 (baseline), TFRC was down-regulated in PMBCs, mDCs, and B-cells at Day 7 post vaccination with FluMist. No change in TFRC expression was observed in monocytes or pDCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TGFB1 response
  • Description: Compared to Day 0 (baseline), TGFB1 was down-regulated in monocytes post vaccination with FluMist. No change in TGFB1 expression was observed in PMBCs, mDCs, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TGFBR2 response
  • Description: Compared to Day 0 (baseline), TGFBR2 was up-regulated in mDCs post vaccination with FluMist. No change in TGFBR2 expression was observed in PMBCs, monocytes, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TICAM1 response
  • Description: Compared to Day 0 (baseline), TICAM1 was down-regulated in mDCs post vaccination with FluMist. No change in TICAM1 expression was observed in PMBCs, monocytes, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TLR6 response
  • Description: Compared to Day 0 (baseline), TLR6 was up-regulated in mDCs and pDCs post vaccination with FluMist. No change in TLR6 expression was observed in PMBCs, monocytes, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TLR7 response
  • Description: Compared to Day 0 (base line), TLR7 was up-regulated in PMBCs and pDCs but was down-regulated in B-cells at Day 7 post vaccination with FluMist. No change in TLR7 expression was observed in monocytes or mDCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TLR8 response
  • Description: Compared to Day 0 (baseline), TLR8 was up-regulated in monocytes and mDCs but down-regulated in pDCs post vaccination with FluMist. No change in TLR8 expression was observed in PMBCs or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TNF response
  • Description: Compared to Day 0 (baseline), TNF was up-regulated in monocytes post vaccination with FluMist. No change in TNF expression was observed in PMBCs, monocytes, mDCs, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TNFAIP3 response
  • Description: Compared to Day 0 (baseline), TNFAIP3 was down-regulated in PMBCs and B-cells but up-regulated in monocytes at Day 7 post vaccination with FluMist. No change in TNFAIP3 expression was observed in mDCs or pDCs at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TNFSF10 response
  • Description: Compared to Day 0 (baseline), TNFSF10 was up-regulated in PMBCs and monocytes post vaccination with FluMist. No change in TNSFSF10 expression was observed in mDCs, pDCs, or B-cells at Day 7 post vaccination with FluMist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.

Human Response

• Vaccination Protocol: Flumist was used to vaccinate young healthy human subjects at the age of 18-50 years old. Blood samples were collected from the vaccinees on days 0, 3, and 7 after vaccination. Influenza hemagglutination inhibition assay (HAI) was performed. The peripheral blood mononuclear cells (PBMCs) were isolated. Different cell populations were isolated by flow cytometer. Microarray experiment was then performed using the PBMC samples (Nakaya et al., 2011). The following host responses are UP regulated gene expressions which experienced at least .33 fold increase in expression.
• Host ACER3 response
  • Description: Compared to Day 0, ACER3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host AHCYL1 response
  • Description: Compared to Day 0, AHCYL1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ALDH1A1 response
  • Description: Compared to Day 0, ALDH1A1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host APOBEC3F response
  • Description: Compared to Day 0, APOBEC3F was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host APOBEC3G response
  • Description: Compared to Day 0, APOBEC3G was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ARMC10 response
  • Description: Compared to Day 0, ARMC10 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ARMC10 response
  • Description: Compared to Day 0, ARMC10 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ATP6V1B2 response
  • Description: Compared to Day 0, ATP6V1B2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ATP6V1C1 response
  • Description: Compared to Day 0, ATP6V1C1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011). ATP6V1C1
  • Detailed Gene Information: Click Here.
• Host C14orf119 response
  • Description: Compared to Day 0, C14orf119 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host C15orf29 response
  • Description: Compared to Day 0, C15orf29 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host C3orf1 response
  • Description: Compared to Day 0, C3orf1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CACNA2D3 response
  • Description: Compared to Day 0, CACNA2D3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CALHM2 response
  • Description: Compared to Day 0, CALHM2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CASP1 response
  • Description: Compared to Day 0, CASP1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CBFA2T2 response
  • Description: Compared to Day 0, CBFA2T2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CBR4 response
  • Description: Compared to Day 0, CBR4 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CCDC56 response
  • Description: Compared to Day 0, CCDC56 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CCDC88A response
  • Description: Compared to Day 0, CCDC88A was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CCND3 response
  • Description: Compared to Day 0, CCND3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CCR2 response
  • Description: Compared to Day 0, CCR2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CD14 response
  • Description: Compared to Day 0, CD14 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CD163 response
  • Description: Compared to Day 0, CD163 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CD1D response
  • Description: Compared to Day 0, CD1D was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CD2 response
  • Description: Compared to Day 0, CD2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CD27 response
  • Description: Compared to Day 0, CD27 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CD33 response
  • Description: Compared to Day 0, CD33 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CD36 response
  • Description: Compared to Day 0, CD36 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CDC14A response
  • Description: Compared to Day 0, CDC14A was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CHST15 response
  • Description: Compared to Day 0, CHST15 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CLEC12A response
  • Description: Compared to Day 0, CLEC 12A was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CNDP2 response
  • Description: Compared to Day 0, CNDP2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host COPB2 response
  • Description: Compared to Day 0, COPB2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CREBZF response
  • Description: Compared to Day 0, CREBZF was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CRLS1 response
  • Description: Compared to Day 0, CRLS1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CRYZL1 response
  • Description: Compared to Day 0, CRYZL1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CSF1R from humans response
  • Description: Compared to Day 0, CSF1R was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CTBP2 response
  • Description: Compared to Day 0, CTBP2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CX3CR1 response
  • Description: Compared to Day 0, CX3CR1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CYBB response
  • Description: Compared to Day 0, CYBB was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host CYFIP1 response
  • Description: Compared to Day 0, CYFIP1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host DCAF7 response
  • Description: Compared to Day 0, DCAF7 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host DDX19A response
  • Description: Compared to Day 0, DDX19A was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host DDX60 response
  • Description: Compared to Day 0, DDX60 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host DENND2D response
  • Description: Compared to Day 0, DENND2D was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host DNAJC24 response
  • Description: Compared to Day 0, DNAJC24 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host DPYD response
  • Description: Compared to Day 0, DPYD was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host DPYSL2 response
  • Description: Compared to Day 0, DPYSL2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host DYNC1I2 response
  • Description: Compared to Day 0, DYNC1I2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host EAF2 response
  • Description: Compared to Day 0, EAF2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ECHDC1 response
  • Description: Compared to Day 0, ECHDC1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host EDEM3 response
  • Description: Compared to Day 0, EDEM3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host EEA1 response
  • Description: Compared to Day 0, EEA1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host EIF2S1 response
  • Description: Compared to Day 0, EIF2S1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ELAVL1 response
  • Description: Compared to Day 0, ELAVL1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ELP3 response
  • Description: Compared to Day 0, ELP3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host EOMES response
  • Description: Compared to Day 0, EOMES was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ETNK1 response
  • Description: Compared to Day 0, ETNK1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host EVL response
  • Description: Compared to Day 0, EVL was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host FAM198B response
  • Description: Compared to Day 0, FAM198B was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host FCGR1B response
  • Description: Compared to Day 0, FCGR1B was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host FGD2 response
  • Description: Compared to Day 0, FGD2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host FGD4 response
  • Description: Compared to Day 0, FGD4 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host FGL2 response
  • Description: Compared to Day 0, FGL2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host FKBP15 response
  • Description: Compared to Day 0, FKBP15 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host FKBP5 response
  • Description: Compared to Day 0, FKBP5 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host FYN response
  • Description: Compared to Day 0, FYN was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host G3BP1 response
  • Description: Compared to Day 0, G3BP1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host GAPT response
  • Description: Compared to Day 0, GAPT was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host GGPS1 response
  • Description: Compared to Day 0, GGPS1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host GIMAP1 response
  • Description: Compared to Day 0, GIMAP1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host GIMAP4 response
  • Description: Compared to Day 0, GIMAP4 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host GIMAP6 response
  • Description: Compared to Day 0, GIMAP6 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host GIMAP8 response
  • Description: Compared to Day 0, GIMAP8 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host GPBAR1 response
  • Description: Compared to Day 0, GPBAR1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host GPR171 response
  • Description: Compared to Day 0, GPR171 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host GTF2H1 response
  • Description: Compared to Day 0, GTF2H1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host GUSBP3 response
  • Description: Compared to Day 0, GUSBP3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host HCK response
  • Description: Compared to Day 0, HCK was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host HECA response
  • Description: Compared to Day 0, HECA was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host HERC4 response
  • Description: Compared to Day 0, HERC4 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host HIST1H1D response
  • Description: Compared to Day 0, HIST1H1D was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host HIST1H2BG response
  • Description: Compared to Day 0, HIST1H2BG was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host HNMT response
  • Description: Compared to Day 0, HNMT was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host HSD17B4 response
  • Description: Compared to Day 0, HSD17B4 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host human STAT1 response
  • Description: Compared to Day 0, STAT1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ICAM2 response
  • Description: Compared to Day 0, ICAM2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IDH1 response
  • Description: Compared to Day 0, IHD1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IFI16 response
  • Description: Compared to Day 0, IFI16 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IFI35 response
  • Description: Compared to Day 0, IFI35 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IKZF1 response
  • Description: Compared to Day 0, IKZF1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IL7R response
  • Description: Compared to Day 0, IL7R was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host IRAK3 response
  • Description: Compared to Day 0, IRAK3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host JAK2 response
  • Description: Compared to Day 0, JAK2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host JUN response
  • Description: Compared to Day 0, JUN was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host KCNE3 response
  • Description: Compared to Day 0, KCNE3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host KCTD12 response
  • Description: Compared to Day 0, KCTD12 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host KIAA0907 response
  • Description: Compared to Day 0, KIAA0907 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host KLF6 response
  • Description: Compared to Day 0, KLF6 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host KLF6 response
  • Description: Compared to Day 0, KLF6 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host KLHL6 response
  • Description: Compared to Day 0, KLHL6 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host KLRD1 response
  • Description: Compared to Day 0, KLRD1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host KLRG1 response
  • Description: Compared to Day 0, KLRG1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host KRCC1 response
  • Description: Compared to Day 0, KRCC1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host KRIT1 response
  • Description: Compared to Day 0, KRIT1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host LILRB1 response
  • Description: Compared to Day 0, LILRB1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host LOC100131541 response
  • Description: Compared to Day 0, LOC100131541 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host LOC100131993 response
  • Description: Compared to Day 0, LOC100131993 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host LOC100170939 response
  • Description: Compared to Day 0, LOC100170939 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host LOC100288387 response
  • Description: Compared to Day 0, LOC100288387 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host LOC100288939 response
  • Description: Compared to Day 0, LOC100288939 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host LOC144571 response
  • Description: Compared to Day 0, LOC144571 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host LOC150166 response
  • Description: Compared to Day 0, LOC150166 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host LOC284837 response
  • Description: Compared to Day 0, LOC284837 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host LPXN response
  • Description: Compared to Day 0, LPXN was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host LRRC8D response
  • Description: Compared to Day 0, LRRC8D was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host M6PR response
  • Description: Compared to Day 0, M6PR was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MAP4K4 response
  • Description: Compared to Day 0, MAP4K4 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MARCH1 response
  • Description: Compared to Day 0, MARCH1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MAVS response
  • Description: Compared to Day 0, MAVS was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MEF2C response
  • Description: Compared to Day 0, MEF2C was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MEGF9 response
  • Description: Compared to Day 0, MEGF9 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MESDC2 response
  • Description: Compared to Day 0, MESDC2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host METTL3 response
  • Description: Compared to Day 0, METTL3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host METTL7A response
  • Description: Compared to Day 0, METTL7A was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MFSD8 response
  • Description: Compared to Day 0, MFSD8 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MGAT2 response
  • Description: Compared to Day 0, MGAT2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MGST1 response
  • Description: Compared to Day 0, MGST1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MITD1 response
  • Description: Compared to Day 0, MITD1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MKKS response
  • Description: Compared to Day 0, MKKS was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MLLT3 response
  • Description: Compared to Day 0, MLLT3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MNDA response
  • Description: Compared to Day 0, MNDA was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MON2 response
  • Description: Compared to Day 0, MON2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MOSPD2 response
  • Description: Compared to Day 0, MOSPD2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MPEG1 response
  • Description: Compared to Day 0, MPEG1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MRPS31 response
  • Description: Compared to Day 0, MRPS31 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MS4A14 response
  • Description: Compared to Day 0, MS4A14 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MS4A4A response
  • Description: Compared to Day 0, MS4A4A was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MS4A6A response
  • Description: Compared to Day 0, MS4A6A was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MS4A7 response
  • Description: Compared to Day 0, MS4A7 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MTIF3 response
  • Description: Compared to Day 0, MTIF3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MX1 response
  • Description: Compared to Day 0, MX1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host MYOF response
  • Description: Compared to Day 0, MYOF was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NAGA response
  • Description: Compared to Day 0, NAGA was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NAGK response
  • Description: Compared to Day 0, NAGK was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NAIP response
  • Description: Compared to Day 0, NAIP was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NCOR1 response
  • Description: Compared to Day 0, NCOR1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NDUFA8 response
  • Description: Compared to Day 0, NDUFA8 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NEK7 response
  • Description: Compared to Day 0, NEK7 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NFATC3 response
  • Description: Compared to Day 0, NFATC3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NSUN5 response
  • Description: Compared to Day 0, NSUN5 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NSUN5P1 response
  • Description: Compared to Day 0, NSUN5P1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NSUN5P2 response
  • Description: Compared to Day 0, NSUN5P2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NUMB response
  • Description: Compared to Day 0, NUMB was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NUP210 response
  • Description: Compared to Day 0, NUP210 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host NUP43 response
  • Description: Compared to Day 0, NUP43 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host OAS1 response
  • Description: Compared to Day 0, OAS1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host OAS2 response
  • Description: Compared to Day 0, OAS2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host OAS3 response
  • Description: Compared to Day 0, OAS3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host OSBPL11 response
  • Description: Compared to Day 0, OSBPL11 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PCMT1 response
  • Description: Compared to Day 0, PCMT1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PHF14 response
  • Description: Compared to Day 0, PHF14 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PID1 response
  • Description: Compared to Day 0, PID1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PION response
  • Description: Compared to Day 0, PION was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PLXNB2 response
  • Description: Compared to Day 0, PLXNB2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PMS1 response
  • Description: Compared to Day 0, PMS1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host POC5 response
  • Description: Compared to Day 0, POC5 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host POLK response
  • Description: Compared to Day 0, POLK was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PSEN1 response
  • Description: Compared to Day 0, PSEN1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PTGDR response
  • Description: Compared to Day 0, PTGDR was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host PYCARD response
  • Description: Compared to Day 0, PYCARD was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host QKI response
  • Description: Compared to Day 0, QKI was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host RAB10 response
  • Description: Compared to Day 0, RAB10 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host RALA response
  • Description: Compared to Day 0, RALA was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host RASSF4 response
  • Description: Compared to Day 0, RASSF4 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host RNASE2 response
  • Description: Compared to Day 0, RNASE2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host RNASE6 response
  • Description: Compared to Day 0, RNASE6 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host RNF170 response
  • Description: Compared to Day 0, RNF170 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host RNF213 response
  • Description: Compared to Day 0, RNF213 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ROCK2 response
  • Description: Compared to Day 0, ROCK2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host RTN1 response
  • Description: Compared to Day 0, RTN1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host S100PBP response
  • Description: Compared to Day 0, S100PBP was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SAMD3 response
  • Description: Compared to Day 0, SAMD3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SAMD9L response
  • Description: Compared to Day 0, SAMD9L was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SAMHD1 response
  • Description: Compared to Day 0, SAMHD1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SAP30 response
  • Description: Compared to Day 0, SAP30 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SETDB2 response
  • Description: Compared to Day 0, SETDB2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SETX response
  • Description: Compared to Day 0, SETX was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SGK223 response
  • Description: Compared to Day 0, SGK223 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SGMS2 response
  • Description: Compared to Day 0, SGMS2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SLAMF6 response
  • Description: Compared to Day 0, SLAMF6 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SLAMF7 response
  • Description: Compared to Day 0, SLAMF7 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SLC25A40 response
  • Description: Compared to Day 0, SLC25A40 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SLC35A1 response
  • Description: Compared to Day 0, SLC35A1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SLC35B3 response
  • Description: Compared to Day 0, SLC35B3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SNORA28 response
  • Description: Compared to Day 0, SNORA28 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SNX1 response
  • Description: Compared to Day 0, SNX1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SON response
  • Description: Compared to Day 0, SON was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SOS1 response
  • Description: Compared to Day 0, SOS1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SPN response
  • Description: Compared to Day 0, SPN was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SPTLC2 response
  • Description: Compared to Day 0, SPTLC2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SRGAP2 response
  • Description: Compared to Day 0, SRGAP2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ST6GAL1 response
  • Description: Compared to Day 0, ST6GAL1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host STK17B response
  • Description: Compared to Day 0, STK17B was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host STK38 response
  • Description: Compared to Day 0, STK38 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host STX7 response
  • Description: Compared to Day 0, STX7 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SUV420H1 response
  • Description: Compared to Day 0, SUV420H1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host SYNRG response
  • Description: Compared to Day 0, SYNRG was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TARP response
  • Description: Compared to Day 0, TARP was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TBC1D8 response
  • Description: Compared to Day 0, TBC1D8 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TCF7L2 response
  • Description: Compared to Day 0, TCF7L2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TFCP2 response
  • Description: Compared to Day 0, TFCP2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TFEC response
  • Description: Compared to Day 0, TFEC was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host THYN1 response
  • Description: Compared to Day 0, THYN1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TIA1 response
  • Description: Compared to Day 0, TIA1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TICAM2 response
  • Description: Compared to Day 0, TICAM2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TLR5 from humans response
  • Description: Compared to Day 0, TLR5 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TLR8 response
  • Description: Compared to Day 0, TLR8 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TMEM63A response
  • Description: Compared to Day 0, TMEM63A was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TMEM69 response
  • Description: Compared to Day 0, TMEM69 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TNFSF10 response
  • Description: Compared to Day 0, TNFSF10 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TRAF3IP3 response
  • Description: Compared to Day 0, TRAF3IP3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TRGC2 response
  • Description: Compared to Day 0, TRGC2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TRIM14 response
  • Description: Compared to Day 0, TRIM14 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host TTC17 response
  • Description: Compared to Day 0, TTC17 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host UBE2L3 response
  • Description: Compared to Day 0, UBE2L3 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host UBN2 response
  • Description: Compared to Day 0, UBN2 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host USO1 response
  • Description: Compared to Day 0, USO1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host UTP6 response
  • Description: Compared to Day 0, UTP6 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host VCAN response
  • Description: Compared to Day 0, VCAN was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host VPS35 response
  • Description: Compared to Day 0, VPS35 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host VPS45 response
  • Description: Compared to Day 0, VPS45 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host VPS72 response
  • Description: Compared to Day 0, VPS72 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host XAF1 response
  • Description: Compared to Day 0, XAF1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host XPO1 response
  • Description: Compared to Day 0, XPO1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ZFAND5 response
  • Description: Compared to Day 0, ZFAND5 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ZKSCAN1 response
  • Description: Compared to Day 0, ZKSCAN1 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ZMYM6 response
  • Description: Compared to Day 0, ZMYM6 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ZNF207 response
  • Description: Compared to Day 0, ZNF207 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ZNF573 response
  • Description: Compared to Day 0, ZNF573 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ZNF638 response
  • Description: Compared to Day 0, ZNF638 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.
• Host ZSWIM6 response
  • Description: Compared to Day 0, ZSWIM6 was UP regulated in PBMCs in Homo Sapiens on Day 3 or Day 7 after vaccination with Flumist (Nakaya et al., 2011).
  • Detailed Gene Information: Click Here.

Human Response

• Host age: 30.3 ± 7.2
• Host gender: Both female and male
• Vaccination Protocol: Intranasal immunization (Barría et al., 2013)
• Immune Response: Seventy-nine subjects were given the LAIV FluMist. Blood was collected prior to vaccination and 3 days and 30 days after vaccination. Nasal wash was collected 3 days and 30 days after vaccination. Responses were measured. It was found that 33% of patients developed at least a 2-fold increase in influenza virus–specific immunoglobulin A (IgA) antibodies in nasal wash (Barría et al., 2013).