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VRC-9123 DNA vaccine plasmid

DNA Vaccine Plasmid ID 90
DNA Vaccine Plasmid Name VRC-9123 DNA vaccine plasmid
Plasmid VO ID VO_0005005
Promoter Names CMV/R
Manufacturer VRC/NIAID/Vaccine Pilot Plant operated by SAIC (Frederick, MD)
Plasmid Description single closed-circular plasmid DNA macromolecule, the plasmid DNA was prepared under Good Manufacturing Practices at 4 mg/mL in phosphate buffered saline (PBS) (Ledgerwood et al., 2011)
Related Vaccine(s)
References
Ledgerwood et al., 2011: Ledgerwood JE, Wei CJ, Hu Z, Gordon IJ, Enama ME, Hendel CS, McTamney PM, Pearce MB, Yassine HM, Boyington JC, Bailer R, Tumpey TM, Koup RA, Mascola JR, Nabel GJ, Graham BS. DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials. The Lancet infectious diseases. 2011; 11(12); 916-924. [PubMed: 21975270].